(Q48391151)

11 February 2018

title

Pharmacological profiles of peptide drug candidates for the treatment of Alzheimer's disease. (English)

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10

William A Banks

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author name string

Céline Adessi

1

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Marie-José Frossard

2

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Christophe Boissard

3

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Santiago Fraga

4

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Sylvain Bieler

5

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Thomas Ruckle

6

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Francis Vilbois

7

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Sandra M Robinson

8

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Manfred Mutter

9

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Claudio Soto

11

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language of work or name

English

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publication date

10 February 2003

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11 February 2018

Journal of Biological Chemistry

published in

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volume

278

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issue

16

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page(s)

13905-13911

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Alzheimer's disease and the amyloid cascade hypothesis: ten years on.

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Passage of peptides across the blood-brain barrier: pathophysiological perspectives

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Converting a peptide into a drug: strategies to improve stability and bioavailability

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In vivo reversal of amyloid-beta lesions in rat brain.

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The alpha-helical to beta-strand transition in the amino-terminal fragment of the amyloid beta-peptide modulates amyloid formation

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Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: detection of amyloid aggregation in solution

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Murine tumor necrosis factor alpha is transported from blood to brain in the mouse.

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Action of proteolysis-resistant systemin analogues in wound signalling.

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A stereochemically-constrained enkephalin analog. alpha-Aminoisobutyryl2 methionine5 enkephalinamide

21 January 2018

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Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red.

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Cognitive and behavioral differentiation of frontal lobe degeneration of the non-Alzheimer type and Alzheimer's disease.

21 January 2018

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The metabolism of neuropeptides. The hydrolysis of peptides, including enkephalins, tachykinins and their analogues, by endopeptidase-24.11.

21 January 2018

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Proline specific peptidases

21 January 2018

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Proline specific endo- and exopeptidases

21 January 2018

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Substitutions of hydrophobic amino acids reduce the amyloidogenicity of Alzheimer's disease beta A4 peptides

21 January 2018

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An analysis of side chain interactions and pair correlations within antiparallel beta-sheets: the differences between backbone hydrogen-bonded and non-hydrogen-bonded residue pairs.

21 January 2018

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Effect of solvent on the cis-trans conformational equilibrium of a proline imide bond of short model peptides in solution

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21 January 2018

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Reduction of amyloid load and cerebral damage in a transgenic mouse model of Alzheimer's disease by treatment with a beta-sheet breaker peptide.

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Inhibition of Alzheimer's amyloidosis by peptides that prevent beta-sheet conformation

21 January 2018

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Prolines and amyloidogenicity in fragments of the Alzheimer's peptide beta/A4

21 January 2018

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Angiotensin-converting enzyme insertion/deletion polymorphism modulates the human in vivo metabolism of bradykinin

21 January 2018

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Immunocytochemical localization of endopeptidase-24.11 in cultured neurons from pig striatum

21 January 2018

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Arrest of beta-amyloid fibril formation by a pentapeptide ligand

21 January 2018

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Pseudo-prolines: induction of cis/trans-conformational interconversion by decreased transition state barriers

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M211976200

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11 February 2018

PubMed ID

12578830

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11 February 2018