(Q48402823)

11 February 2018

title

Astrocytic localization of kynurenine aminotransferase II in the rat brain visualized by immunocytochemistry. (English)

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11 February 2018

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Paolo Guidetti

1

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11 February 2018

Gloria E Hoffman

2

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11 February 2018

Miguel Melendez-Ferro

3

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11 February 2018

Edson X Albuquerque

4

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11 February 2018

Robert Schwarcz

5

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11 February 2018

publication date

1 January 2007

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11 February 2018

published in

Glia

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11 February 2018

volume

55

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11 February 2018

issue

1

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11 February 2018

page(s)

78-92

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11 February 2018

Double immunofluorescent staining using two unconjugated primary antisera raised in the same species.

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Targeted deletion of the kynurenine aminotransferase ii gene reveals a critical role of endogenous kynurenic acid in the regulation of synaptic transmission via alpha7 nicotinic receptors in the hippocampus.

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7 January 2021

Developmental changes in brain kynurenic acid concentrations.

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cFos immunoreactivity is enhanced with biotin amplification

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Therapeutic potential of NMDA receptor antagonists in the treatment of alcohol and substance use disorders

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7 January 2021

Cloning and functional expression of a soluble form of kynurenine/alpha-aminoadipate aminotransferase from rat kidney

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Presynaptic kynurenate-sensitive receptors inhibit glutamate release

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Acute and chronic changes in kynurenate formation following an intrastriatal quinolinate injection in rats.

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Neonatal asphyxia in rats: acute effects on cerebral kynurenine metabolism

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Comparison of the neurochemical and behavioral effects resulting from the inhibition of kynurenine hydroxylase and/or kynureninase

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7 January 2021

Roles of NMDA receptor activity and nitric oxide production in brain development

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7 January 2021

The role of glutamine transaminase K (GTK) in sulfur and alpha-keto acid metabolism in the brain, and in the possible bioactivation of neurotoxicants

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The NMDA receptor glycine modulatory site: a therapeutic target for improving cognition and reducing negative symptoms in schizophrenia

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Kynurenine hydroxylase inhibitors reduce ischemic brain damage: studies with (m-nitrobenzoyl)-alanine (mNBA) and 3,4-dimethoxy-[-N-4-(nitrophenyl)thiazol-2yl]-benzenesulfonamide (Ro 61-8048) in models of focal or global brain ischemia.

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Expression of kynurenine aminotransferase in the subplate of the rat and its possible role in the regulation of programmed cell death

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7 January 2021

Localization of kynurenine aminotransferase immunoreactivity in the rat hippocampus

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Kynurenic acid levels are elevated in the cerebrospinal fluid of patients with schizophrenia

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Pharmacological elevation of endogenous kynurenic acid levels activates nigral dopamine neurons

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7 January 2021

Synthesis and metabolism of L-kynurenine in rat brain

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l-Kynurenine Its synthesis and possible regulatory function in brain

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7 January 2021

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Metabolism of [5-3H]kynurenine in the rat brain in vivo: evidence for the existence of a functional kynurenine pathway

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7 January 2021

Early kynurenergic impairment in Huntington's disease and in a transgenic animal model

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7 January 2021

Kynurenine pathway metabolism in human astrocytes: a paradox for neuronal protection

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7 January 2021

Quinolinic acid and kynurenine pathway metabolism in inflammatory and non-inflammatory neurological disease

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7 January 2021

The brain metabolite kynurenic acid inhibits alpha7 nicotinic receptor activity and increases non-alpha7 nicotinic receptor expression: physiopathological implications

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7 January 2021

Kynurenate production by cultured human astrocytes

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7 January 2021

Kynurenine aminotransferase in the supratentorial dura mater of the rat: effect of stimulation of the trigeminal ganglion

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7 January 2021

A missense mutation in kynurenine aminotransferase-1 in spontaneously hypertensive rats.

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7 January 2021

Kynurenic acid is present in the rat brain and its content increases during development and aging processes

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7 January 2021

Kynurenine administered together with probenecid markedly inhibits pentylenetetrazol-induced seizures. An electrophysiological and behavioural study

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7 January 2021

Effects of nicotinic stimulation on cognitive performance

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7 January 2021

Regional changes in kynurenic acid, quinolinic acid, and glial fibrillary acidic protein concentrations in the fetal sheep brain after experimentally induced placental insufficiency

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20432

7 January 2021

Activation of noradrenergic locus coeruleus neurons by clozapine and haloperidol: involvement of glutamatergic mechanisms

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https://api.crossref.org/works/10.1002%2FGLIA.20432

7 January 2021

Role of alpha7 nicotinic receptors in nicotine dependence and implications for psychiatric illness

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https://api.crossref.org/works/10.1002%2FGLIA.20432

7 January 2021

Modulation of the kynurenine pathway in search for new neuroprotective agents. Synthesis and preliminary evaluation of (m-nitrobenzoyl)alanine, a potent inhibitor of kynurenine-3-hydroxylase.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20432

7 January 2021

Modulators of the Kynurenine Pathway of Tryptophan Metabolism: Synthesis and Preliminary Biological Evaluation of (S)-4-(Ethylsulfonyl)benzoylalanine, a Potent and Selective Kynurenine Aminotransferase II (KAT II) Inhibitor

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7 January 2021

Unconventional ligands and modulators of nicotinic receptors

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7 January 2021

Homeostatic plasticity and NMDA receptor trafficking

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20432

7 January 2021

Nanomolar concentrations of kynurenic acid reduce extracellular dopamine levels in the striatum

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https://api.crossref.org/works/10.1002%2FGLIA.20432

7 January 2021

Age-dependent decrease of retinal kynurenate and kynurenine aminotransferases in DBA/2J mice, a model of ocular hypertension.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20432

7 January 2021

Immunocytochemical localization of kynurenine aminotransferase in the rat striatum: a light and electron microscopic study

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20432

7 January 2021

Demonstration of kynurenine aminotransferases I and II and characterization of kynurenic acid synthesis in cultured cerebral cortical neurons.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20432

7 January 2021

Endogenous kynurenate controls the vulnerability of striatal neurons to quinolinate: Implications for Huntington's disease

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7 January 2021

Manipulation of brain kynurenines: glial targets, neuronal effects, and clinical opportunities

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https://api.crossref.org/works/10.1002%2FGLIA.20432

7 January 2021

Increased cortical kynurenate content in schizophrenia

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https://api.crossref.org/works/10.1002%2FGLIA.20432

7 January 2021

High-affinity uptake of L-kynurenine by a Na+-independent transporter of neutral amino acids in astrocytes

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20432

7 January 2021

Comparative distribution of nicotinic receptor subtypes during development, adulthood and aging: an autoradiographic study in the rat brain

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20432

7 January 2021

Rat brain slices produce and liberate kynurenic acid upon exposure to L-kynurenine

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20432

7 January 2021

On the disposition of intrahippocampally injected kynurenic acid in the rat.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20432

7 January 2021

Demonstration of kynurenine aminotransferases I and II and characterization of kynurenic acid synthesis in oligodendrocyte cell line (OLN-93).

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20432

7 January 2021

Kynurenate and 7-chlorokynurenate formation in chronically epileptic rats

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20432

7 January 2021

Biochemical and phenotypic abnormalities in kynurenine aminotransferase II-deficient mice

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20432

7 January 2021

Identifiers

DOI

10.1002/GLIA.20432

1 reference

11 February 2018

PubMed ID

17024659

1 reference

11 February 2018