(Q48418722)

English

Loss of Maged1 results in obesity, deficits of social interactions, impaired sexual behavior and severe alteration of mature oxytocin production in the hypothalamus

scientific article published on 2 August 2012

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/22865874

Loss of Maged1 results in obesity, deficits of social interactions, impaired sexual behavior and severe alteration of mature oxytocin production in the hypothalamus (English)

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/22865874

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based on heuristic

inferred from title

Jacques L. Michaud

4

object named as

Jacques L Michaud

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/22865874

author name string

Carlos Dombret

1

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/22865874

Tuan Nguyen

2

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/22865874

Olivier Schakman

3

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/22865874

Hélène Hardin-Pouzet

5

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/22865874

Mathieu J M Bertrand

6

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/22865874

Olivier De Backer

7

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/22865874

publication date

2 August 2012

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Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/22865874

Human Molecular Genetics

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/22865874

21

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/22865874

21

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/22865874

4703-4717

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/22865874

1 reference

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Key role for gene dosage and synaptic homeostasis in autism spectrum disorders

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An immunochemical analysis of oxytocin and vasopressin prohormone processing in vivo

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Mechanisms of the anti-obesity effects of oxytocin in diet-induced obese rats

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Oxytocin and vasopressin in the human brain: social neuropeptides for translational medicine

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The human MAGEL2 gene and its mouse homologue are paternally expressed and mapped to the Prader-Willi region

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The human necdin gene, NDN, is maternally imprinted and located in the Prader-Willi syndrome chromosomal region

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Prader-Willi syndrome.

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Prader-Willi syndrome and autism spectrum disorders: an evolving story

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Disruption of the mouse necdin gene results in early post-natal lethality

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Disruption of the mouse Necdin gene results in hypothalamic and behavioral alterations reminiscent of the human Prader-Willi syndrome.

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21 January 2018

Inactivation of the mouse Magel2 gene results in growth abnormalities similar to Prader-Willi syndrome

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21 January 2018

Impaired hypothalamic regulation of endocrine function and delayed counterregulatory response to hypoglycemia in Magel2-null mice.

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21 January 2018

Loss of magel2, a candidate gene for features of Prader-Willi syndrome, impairs reproductive function in mice

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21 January 2018

The imprinted gene Magel2 regulates normal circadian output.

1 reference

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21 January 2018

Regionally reduced brain volume, altered serotonin neurochemistry, and abnormal behavior in mice null for the circadian rhythm output gene Magel2.

1 reference

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21 January 2018

Comparative expression analysis of the MAGED genes during embryogenesis and brain development

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21 January 2018

NRAGE, a p75NTR adaptor protein, is required for developmental apoptosis in vivo.

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21 January 2018

Maged1, a new regulator of skeletal myogenic differentiation and muscle regeneration.

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21 January 2018

Social approach and repetitive behavior in eleven inbred mouse strains

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21 January 2018

Automated apparatus for quantitation of social approach behaviors in mice.

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Housing conditions and stimulus females: a robust social discrimination task for studying male rodent social recognition

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Ultrasonic vocalizations: a tool for behavioural phenotyping of mouse models of neurodevelopmental disorders.

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Female mice respond to male ultrasonic 'songs' with approach behaviour

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Autism-like behavioral phenotypes in BTBR T+tf/J mice

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Shank3 mutant mice display autistic-like behaviours and striatal dysfunction

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21 January 2018

Abnormal hypothalamic oxytocin system in fibroblast growth factor 8-deficient mice

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21 January 2018

Synthesis, Transport, and Release of Posterior Pituitary Hormones

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Biosynthesis of vasopressin, oxytocin, and neurophysins: isolation and characterization of two common precursors (propressophysin and prooxyphysin).

1 reference

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21 January 2018

Social amnesia in mice lacking the oxytocin gene.

1 reference

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21 January 2018

A conditional knockout mouse line of the oxytocin receptor.

1 reference

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21 January 2018

Behavioural studies using temporal and spatial inactivation of the oxytocin receptor.

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Pharmacologic rescue of impaired cognitive flexibility, social deficits, increased aggression, and seizure susceptibility in oxytocin receptor null mice: a neurobehavioral model of autism.

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21 January 2018

CD38 is critical for social behaviour by regulating oxytocin secretion

1 reference

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21 January 2018

When MAGE meets RING: insights into biological functions of MAGE proteins

1 reference

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Interaction of MAGED1 with nuclear receptors affects circadian clock function

1 reference

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Carboxypeptidase E

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Peptidylglycine alpha-amidating monooxygenase: an ascorbate-requiring enzyme

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Proteolysis in Neuropeptide Processing and Other Neural Functions

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21 January 2018

Oxytocin is required for nursing but is not essential for parturition or reproductive behavior

1 reference

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21 January 2018

Pervasive social deficits, but normal parturition, in oxytocin receptor-deficient mice

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Deficiency in mouse oxytocin prevents milk ejection, but not fertility or parturition.

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Disruption of sexual behavior in male aromatase-deficient mice lacking exons 1 and 2 of the cyp19 gene

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Restoration of male sexual behavior by adult exogenous estrogens in male aromatase knockout mice

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Male aromatase-knockout mice exhibit normal levels of activity, anxiety and "depressive-like" symptomatology

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Influence of oxytocin on feeding behavior in the rat.

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Oxytocin inhibits food and fluid intake in rats

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Oxytocin and an oxytocin agonist administered centrally decrease food intake in rats

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Sim1 haploinsufficiency causes hyperphagia, obesity and reduction of the paraventricular nucleus of the hypothalamus

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Development of neuroendocrine lineages requires the bHLH-PAS transcription factor SIM1.

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Oxytocin deficiency mediates hyperphagic obesity of Sim1 haploinsufficient mice

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Input organization and plasticity of hypocretin neurons: possible clues to obesity's association with insomnia.

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Brain oxytocin: a key regulator of emotional and social behaviours in both females and males

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Centrally released oxytocin mediates mating-induced anxiolysis in male rats

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Oxytocin reduces anxiety via ERK1/2 activation: local effect within the rat hypothalamic paraventricular nucleus.

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Anxiolytic-like activity of oxytocin in male mice: behavioral and autonomic evidence, therapeutic implications

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Enhanced corticosterone concentrations and attenuated Fos expression in the medial amygdala of female oxytocin knockout mice exposed to psychogenic stress

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Anxiety and stress responses in female oxytocin deficient mice

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Oxytocin receptor and Mecp2 308/Y knockout mice exhibit altered expression of autism-related social behaviors.

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Oxytocin receptor knockout mice display deficits in the expression of autism-related behaviors

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MAGE-D1 regulates expression of depression-like behavior through serotonin transporter ubiquitylation.

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Evidence that oxytocin exerts anxiolytic effects via oxytocin receptor expressed in serotonergic neurons in mice

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Origin of projections from the midbrain raphe nuclei to the hypothalamic paraventricular nucleus in the rat: a combined retrograde and anterograde tracing study.

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Genomic and epigenetic evidence for oxytocin receptor deficiency in autism

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Association of the oxytocin receptor gene (OXTR) in Caucasian children and adolescents with autism

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Positive association of the oxytocin receptor gene (OXTR) with autism in the Chinese Han population

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Plasma oxytocin levels in autistic children.

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Oxytocin and autistic disorder: alterations in peptide forms

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Intranasal oxytocin improves emotion recognition for youth with autism spectrum disorders

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Structural variation of chromosomes in autism spectrum disorder

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Sim2 contributes to neuroendocrine hormone gene expression in the anterior hypothalamus

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Identifiers

10.1093/HMG/DDS310

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/22865874

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/22865874

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