(Q48445377)

11 February 2018

title

The complex relationship between soluble and insoluble tau in tauopathies revealed by efficient dephosphorylation and specific antibodies. (English)

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11 February 2018

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11 February 2018

Jean-Pierre Brion

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11 February 2018

author name string

Gibb GM

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11 February 2018

de Silva R

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11 February 2018

Boutajangout A

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11 February 2018

Revesz T

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11 February 2018

Lees AJ

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11 February 2018

Anderton BH

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11 February 2018

language of work or name

English

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publication date

1 November 2002

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11 February 2018

published in

FEBS Letters

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11 February 2018

volume

531

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11 February 2018

page(s)

538-542

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11 February 2018

issue

3

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11 February 2018

Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

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A68 proteins in Alzheimer's disease are composed of several tau isoforms in a phosphorylated state which affects their electrophoretic mobilities

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Comparative biochemistry of tau in progressive supranuclear palsy, corticobasal degeneration, FTDP-17 and Pick's disease

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Characterization of two pathological tau protein, variants in Alzheimer brain cortices.

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Relationship of the extended tau haplotype to tau biochemistry and neuropathology in progressive supranuclear palsy

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Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms

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Discovery of a protein phosphatase activity encoded in the genome of bacteriophage lambda. Probable identity with open reading frame 221.

21 January 2018

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The microtubule binding of Tau and high molecular weight Tau in apoptotic PC12 cells is impaired because of altered phosphorylation.

21 January 2018

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New phosphorylation sites identified in hyperphosphorylated tau (paired helical filament-tau) from Alzheimer's disease brain using nanoelectrospray mass spectrometry

21 January 2018

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PHF-tau from Alzheimer's brain comprises four species on SDS-PAGE which can be mimicked by in vitro phosphorylation of human brain tau by glycogen synthase kinase-3 beta.

21 January 2018

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Neurofilament monoclonal antibodies RT97 and 8D8 recognize different modified epitopes in paired helical filament-tau in Alzheimer's disease.

21 January 2018

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Tau in Alzheimer neurofibrillary tangles. N- and C-terminal regions are differentially associated with paired helical filaments and the location of a putative abnormal phosphorylation site

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Argyrophilic grain disease is a sporadic 4-repeat tauopathy

21 January 2018

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Transgenic expression of the shortest human tau affects its compartmentalization and its phosphorylation as in the pretangle stage of Alzheimer's disease

21 January 2018

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The distribution of tau in the mammalian central nervous system

21 January 2018

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Monoclonal antibody PHF-1 recognizes tau protein phosphorylated at serine residues 396 and 404.

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Differential expression of exons 10 and 11 in normal tau and tau associated with paired helical filaments

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Regulated phosphorylation and dephosphorylation of tau protein: effects on microtubule interaction, intracellular trafficking and neurodegeneration

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Dysregulation of human brain microtubule-associated tau mRNA maturation in myotonic dystrophy type 1.

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Late-onset frontotemporal dementia with a novel exon 1 (Arg5His) tau gene mutation

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Alpha-synuclein-positive structures in cases with sporadic Alzheimer's disease: morphology and its relationship to tau aggregation.

21 January 2018

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Phosphorylation of specific sets of tau isoforms reflects different neurofibrillary degeneration processes.

21 January 2018

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Neurofibrillary degeneration in progressive supranuclear palsy and corticobasal degeneration: tau pathologies with exclusively "exon 10" isoforms

21 January 2018

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Sporadic Pick's disease: a tauopathy characterized by a spectrum of pathological tau isoforms in gray and white matter

21 January 2018

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Signature tau neuropathology in gray and white matter of corticobasal degeneration

21 January 2018

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Distinct isoforms of tau aggregated in neurons and glial cells in brains of patients with Pick's disease, corticobasal degeneration and progressive supranuclear palsy.

21 January 2018

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10.1016/S0014-5793(02)03611-6

7 January 2021

Identifiers

DOI

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11 February 2018

PubMed ID

12435607

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11 February 2018