(Q48449125)

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Mesotrypsin, a brain trypsin, activates selectively proteinase-activated receptor-1, but not proteinase-activated receptor-2, in rat astrocytes.

scientific article published on 11 August 2006

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28 December 2019

Mesotrypsin, a brain trypsin, activates selectively proteinase-activated receptor-1, but not proteinase-activated receptor-2, in rat astrocytes (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16903872%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

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Miklós Sahin-Tóth

5

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28 December 2019

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Yingfei Wang

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28 December 2019

Weibo Luo

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28 December 2019

Thomas Wartmann

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28 December 2019

Walter Halangk

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28 December 2019

Georg Reiser

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28 December 2019

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11 August 2006

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28 December 2019

Journal of Neurochemistry

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28 December 2019

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28 December 2019

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28 December 2019

759-769

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28 December 2019

Molecular cloning, expression and potential functions of the human proteinase-activated receptor-2

1 reference

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21 January 2018

Glycosylation and the activation of proteinase-activated receptor 2 (PAR(2)) by human mast cell tryptase

1 reference

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Restricted ability of human mast cell tryptase to activate proteinase-activated receptor-2 in rat aorta

1 reference

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Glycosylation of human proteinase-activated receptor-2 (hPAR2): role in cell surface expression and signalling

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Trypsin IV, a novel agonist of protease-activated receptors 2 and 4.

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Protease-activated receptor-2 (PAR-2) in brain microvascular endothelium and its regulation by plasmin and elastase

1 reference

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21 January 2018

Expression and functional analysis of rat P23, a gut hormone-inducible isoform of trypsin, reveals its resistance to proteinaceous trypsin inhibitors

1 reference

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21 January 2018

Activity of recombinant trypsin isoforms on human proteinase-activated receptors (PAR): mesotrypsin cannot activate epithelial PAR-1, -2, but weakly activates brain PAR-1.

1 reference

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21 January 2018

Primary glial cultures as a model for studying hormone action

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21 January 2018

Crystal structure reveals basis for the inhibitor resistance of human brain trypsin

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21 January 2018

Human anionic trypsinogen: properties of autocatalytic activation and degradation and implications in pancreatic diseases

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21 January 2018

Two types of protease-activated receptors (PAR-1 and PAR-2) mediate calcium signaling in rat retinal ganglion cells RGC-5.

1 reference

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21 January 2018

Enhanced GFAP expression in astrocytes of transgenic mice expressing the human brain-specific trypsinogen IV.

1 reference

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21 January 2018

PAR3 is a cofactor for PAR4 activation by thrombin

1 reference

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21 January 2018

Genetic and biochemical characterization of the E32del polymorphism in human mesotrypsinogen

1 reference

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21 January 2018

Activation of protease-activated receptor-1 triggers astrogliosis after brain injury.

1 reference

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21 January 2018

Identification and expression of the cDNA-encoding human mesotrypsin(ogen), an isoform of trypsin with inhibitor resistance

1 reference

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21 January 2018

Molecular cloning and functional expression of the gene encoding the human proteinase-activated receptor 2

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21 January 2018

Human cationic trypsinogen. Role of Asn-21 in zymogen activation and implications in hereditary pancreatitis

1 reference

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21 January 2018

Human mesotrypsin defies natural trypsin inhibitors: from passive resistance to active destruction

1 reference

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21 January 2018

Identification of proteins according to biological activity following separation by two-dimensional isoelectric focusing/sodium dodecyl sulfate gel electrophoresis: Analysis of human exocrine pancreatic proteins

1 reference

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21 January 2018

The protease thrombin is an endogenous mediator of hippocampal neuroprotection against ischemia at low concentrations but causes degeneration at high concentrations

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21 January 2018

Four different types of protease-activated receptors are widely expressed in the brain and are up-regulated in hippocampus by severe ischemia.

1 reference

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21 January 2018

Participation of protease-activated receptor-1 in thrombin-induced microglial activation

1 reference

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21 January 2018

Human Mesotrypsin Is a Unique Digestive Protease Specialized for the Degradation of Trypsin Inhibitors

1 reference

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21 January 2018

The role of the Ca2+-sensitive tyrosine kinase Pyk2 and Src in thrombin signalling in rat astrocytes

1 reference

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21 January 2018

Four subtypes of protease-activated receptors, co-expressed in rat astrocytes, evoke different physiological signaling

1 reference

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21 January 2018

Thrombin (PAR-1)-induced proliferation in astrocytes via MAPK involves multiple signaling pathways

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21 January 2018

Expression of protease-activated receptors (PARs) in OLN-93 oligodendroglial cells and mechanism of PAR-1-induced calcium signaling

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21 January 2018

Protease-activated receptor-1 protects rat astrocytes from apoptotic cell death via JNK-mediated release of the chemokine GRO/CINC-1.

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21 January 2018

Cloning of the cDNA encoding human brain trypsinogen and characterization of its product

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21 January 2018

The role of thrombin and thrombin receptors in ischemic, hemorrhagic and traumatic brain injury: deleterious or protective?

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Cloning and characterization of human protease-activated receptor 4

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21 January 2018

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