(Q48468481)

English

Therapeutically effective antibodies against amyloid-beta peptide target amyloid-beta residues 4-10 and inhibit cytotoxicity and fibrillogenesis.

scientific article published on 15 October 2002

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scholarly article

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13 December 2019

Therapeutically effective antibodies against amyloid-beta peptide target amyloid-beta residues 4-10 and inhibit cytotoxicity and fibrillogenesis (English)

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13 December 2019

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Peter Henry St George-Hyslop

18

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13 December 2019

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McLaurin J

1

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13 December 2019

Cecal R

2

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13 December 2019

Kierstead ME

3

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13 December 2019

Tian X

4

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13 December 2019

Phinney AL

5

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13 December 2019

Manea M

6

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13 December 2019

French JE

7

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13 December 2019

Lambermon MH

8

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13 December 2019

Darabie AA

9

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13 December 2019

Brown ME

10

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13 December 2019

Janus C

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13 December 2019

Chishti MA

12

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13 December 2019

Horne P

13

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13 December 2019

Westaway D

14

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13 December 2019

Fraser PE

15

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13 December 2019

Mount HT

16

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13 December 2019

Przybylski M

17

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13 December 2019

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15 October 2002

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13 December 2019

Nature Medicine

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13 December 2019

8

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13 December 2019

1263-1269

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13 December 2019

11

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13 December 2019

https://scigraph.springernature.com/pub.10.1038/nm790

0 references

Alzheimer's disease and Abeta toxicity: from top to bottom

1 reference

https://api.crossref.org/works/10.1038%2FNM790

21 January 2018

Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695.

1 reference

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21 January 2018

A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FNM790

21 January 2018

Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

1 reference

https://api.crossref.org/works/10.1038%2FNM790

21 January 2018

A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease.

1 reference

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21 January 2018

Nerve inflammation halts trial for Alzheimer's drug.

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Fourier transform ion cyclotron resonance mass spectrometry: a primer

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21 January 2018

Mass spectrometric mapping of protein epitope structures of myocardial infarct markers myoglobin and troponin T.

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21 January 2018

Molecular epitope identification by limited proteolysis of an immobilized antigen-antibody complex and mass spectrometric peptide mapping

1 reference

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21 January 2018

Characterization of a discontinuous epitope of the human immunodeficiency virus (HIV) core protein p24 by epitope excision and differential chemical modification followed by mass spectrometric peptide mapping analysis

1 reference

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21 January 2018

Monoclonal antibodies inhibit in vitro fibrillar aggregation of the Alzheimer beta-amyloid peptide

1 reference

https://api.crossref.org/works/10.1038%2FNM790

21 January 2018

Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

1 reference

https://api.crossref.org/works/10.1038%2FNM790

21 January 2018

Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FNM790

21 January 2018

Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models

1 reference

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21 January 2018

Disaggregation of Alzheimer beta-amyloid by site-directed mAb.

1 reference

https://api.crossref.org/works/10.1038%2FNM790

21 January 2018

Modulation of Alzheimer's beta-amyloid neurotoxicity by site-directed single-chain antibody.

1 reference

https://api.crossref.org/works/10.1038%2FNM790

21 January 2018

Comparative analysis of amyloid-beta chemical structure and amyloid plaque morphology of transgenic mouse and Alzheimer's disease brains

1 reference

https://api.crossref.org/works/10.1038%2FNM790

21 January 2018

APP transgenic mice Tg2576 accumulate Abeta peptides that are distinct from the chemically modified and insoluble peptides deposited in Alzheimer's disease senile plaques.

1 reference

https://api.crossref.org/works/10.1038%2FNM790

21 January 2018

Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FNM790

21 January 2018

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

1 reference

https://api.crossref.org/works/10.1038%2FNM790

21 January 2018

Isolation and identification of the plasma membrane-associated intracellular protein reggie-2 from goldfish brain by chromatography and Fourier-transform ion cyclotron resonance mass spectrometry

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21 January 2018

A one-step procedure for biotinylation and chemical cross-linking of lymphocyte surface and intracellular membrane-associated molecules

1 reference

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21 January 2018

Inositol stereoisomers stabilize an oligomeric aggregate of Alzheimer amyloid beta peptide and inhibit abeta -induced toxicity.

1 reference

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21 January 2018

Age-related deposition of glia-associated fibrillar material in brains of C57BL/6 mice

1 reference

https://api.crossref.org/works/10.1038%2FNM790

21 January 2018

Amyloid beta-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates

1 reference

https://api.crossref.org/works/10.1038%2FNM790

7 January 2021

based on heuristic

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Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Oligomerization of peptides analogous to the cytoplasmic domains of coatomer receptors revealed by mass spectrometry

1 reference

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7 January 2021

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Synthesis and structural characterization of human-identical lung surfactant SP-C protein

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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Europe PubMed Central

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13 December 2019

1 reference

Europe PubMed Central

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13 December 2019

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