(Q48485483)

11 February 2018

title

Alternative lengthening of telomeres is enriched in, and impacts survival of TP53 mutant pediatric malignant brain tumors. (English)

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11 February 2018

author

Marc Remke

14

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11 February 2018

Jonathan D. Wasserman

object named as

Jonathan Wasserman

9

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Irene L Andrulis

20

object named as

Irene L Andrulis

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11 February 2018

26

Eric Bouffet

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11 February 2018

31

Uri Tabori

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11 February 2018

30

Cynthia Hawkins

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11 February 2018

24

James T Rutka

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11 February 2018

author name string

Joshua Mangerel

1

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11 February 2018

Aryeh Price

2

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11 February 2018

Pedro Castelo-Branco

3

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11 February 2018

Jack Brzezinski

4

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11 February 2018

Pawel Buczkowicz

5

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11 February 2018

Patricia Rakopoulos

6

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11 February 2018

Diana Merino

7

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11 February 2018

Berivan Baskin

8

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11 February 2018

Matthew Mistry

10

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11 February 2018

Mark Barszczyk

11

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11 February 2018

Daniel Picard

12

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11 February 2018

Stephen Mack

13

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11 February 2018

Hava Starkman

15

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11 February 2018

Cynthia Elizabeth

16

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11 February 2018

Cindy Zhang

17

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11 February 2018

Noa Alon

18

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11 February 2018

Jodi Lees

19

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11 February 2018

Jay S Wunder

21

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11 February 2018

Nada Jabado

22

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11 February 2018

Donna L Johnston

23

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11 February 2018

Peter B Dirks

25

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11 February 2018

Michael D Taylor

27

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11 February 2018

Annie Huang

28

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11 February 2018

David Malkin

29

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11 February 2018

publication date

15 October 2014

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11 February 2018

published in

Acta Neuropathologica

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11 February 2018

volume

128

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11 February 2018

issue

6

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11 February 2018

page(s)

853-862

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11 February 2018

https://scigraph.springernature.com/pub.10.1007/s00401-014-1348-1

exact match

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cites work

The alternative lengthening of telomere phenotype is significantly associated with loss of ATRX expression in high-grade pediatric and adult astrocytomas: a multi-institutional study of 214 astrocytomas

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1348-1

Human telomeres contain at least three types of G-rich repeat distributed non-randomly

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00401-014-1348-1

Prognostic significance of histological grading, p53 status, YKL-40 expression, and IDH1 mutations in pediatric high-grade gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1348-1

Telomere length measurement-caveats and a critical assessment of the available technologies and tools

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1348-1

Homologous recombination in human telomerase‐positive and ALT cells occurs with the same frequency

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1348-1

High expression of BMP pathway genes distinguishes a subset of atypical teratoid/rhabdoid tumors associated with shorter survival

21 January 2018

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Methylation of the TERT promoter and risk stratification of childhood brain tumours: an integrative genomic and molecular study.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00401-014-1348-1

Alternative lengthening of telomeres: models, mechanisms and implications

21 January 2018

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Association of mutant TP53 with alternative lengthening of telomeres and favorable prognosis in glioma.

21 January 2018

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Treatment Options for Medulloblastoma and CNS Primitive Neuroectodermal Tumor (PNET)

21 January 2018

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Telomere maintenance in childhood primitive neuroectodermal brain tumors

21 January 2018

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Prognostic significance of telomere maintenance mechanisms in pediatric high-grade gliomas

21 January 2018

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Alternative Lengthening of Telomeres is characterized by reduced compaction of telomeric chromatin

21 January 2018

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Hallmarks of Cancer: The Next Generation

21 January 2018

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Altered telomeres in tumors with ATRX and DAXX mutations

21 January 2018

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Prevalence of the alternative lengthening of telomeres telomere maintenance mechanism in human cancer subtypes

21 January 2018

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TERT promoter mutations in familial and sporadic melanoma

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00401-014-1348-1

Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00401-014-1348-1

Cross-species genomics matches driver mutations and cell compartments to model ependymoma

21 January 2018

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Paediatric and adult malignant glioma: close relatives or distant cousins?

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00401-014-1348-1

Whole-exome sequencing identifies ATRX mutation as a key molecular determinant in lower-grade glioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1348-1

TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00401-014-1348-1

Molecular diagnostics in paediatric glial tumours

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00401-014-1348-1

Distribution of TERT promoter mutations in pediatric and adult tumors of the nervous system.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00401-014-1348-1

Frequent ATRX mutations and loss of expression in adult diffuse astrocytic tumors carrying IDH1/IDH2 and TP53 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1348-1

Epigenomic alterations define lethal CIMP-positive ependymomas of infancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1348-1

Breakpoint profiling of 64 cancer genomes reveals numerous complex rearrangements spawned by homology-independent mechanisms

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00401-014-1348-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1348-1

Telomeric armor: the layers of end protection

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00401-014-1348-1

C11orf95-RELA fusions drive oncogenic NF-κB signalling in ependymoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1348-1

Expression of p53 and prognosis in children with malignant gliomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1348-1

Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1348-1

TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00401-014-1348-1

Pediatric high-grade glioma: molecular genetic clues for innovative therapeutic approaches

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00401-014-1348-1

Children are not just little adults: recent advances in understanding of diffuse intrinsic pontine glioma biology

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00401-014-1348-1

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1348-1

Excessive genomic DNA copy number variation in the Li-Fraumeni cancer predisposition syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1348-1

Tumor protein p53 (TP53) testing and Li-Fraumeni syndrome : current status of clinical applications and future directions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1348-1

TP53 alterations determine clinical subgroups and survival of patients with choroid plexus tumors

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00401-014-1348-1

The role of telomere maintenance in the spontaneous growth arrest of pediatric low-grade gliomas

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00401-014-1348-1

Telomerase promoter mutations in cancer: an emerging molecular biomarker?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1348-1

Telomerase inhibition induces acute ATM-dependent growth arrest in human astrocytomas

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00401-014-1348-1

Subgroup-specific prognostic implications of TP53 mutation in medulloblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1348-1

10.1007/S00401-014-1348-1

21 January 2018

Identifiers

DOI

1 reference

11 February 2018

PubMed ID

25315281

1 reference

11 February 2018