(Q48487209)

English

Protein kinase C activation increases release of secreted amyloid precursor protein without decreasing Abeta production in human primary neuron cultures.

scientific article published in April 1998

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

12 February 2018

http://europepmc.org/abstract/MED/9526007

Protein kinase C activation increases release of secreted amyloid precursor protein without decreasing Abeta production in human primary neuron cultures (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792603&resulttype=core&format=json

12 May 2020

author name string

A C LeBlanc

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792603&resulttype=core&format=json

12 May 2020

M Koutroumanis

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792603&resulttype=core&format=json

12 May 2020

C G Goodyer

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792603&resulttype=core&format=json

12 May 2020

language of work or name

0 references

publication date

1 April 1998

1 reference

Europe PubMed Central

PubMed publication ID

12 February 2018

http://europepmc.org/abstract/MED/9526007

Journal of Neuroscience

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792603&resulttype=core&format=json

12 May 2020

18

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792603&resulttype=core&format=json

12 May 2020

8

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792603&resulttype=core&format=json

12 May 2020

2907-2913

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792603&resulttype=core&format=json

12 May 2020

Regulation by phorbol esters of amyloid precursor protein release from Swiss 3T3 fibroblasts overexpressing protein kinase C alpha.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tyrosine phosphorylation-dependent stimulation of amyloid precursor protein secretion by the m3 muscarinic acetylcholine receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C alteration is an early biochemical marker in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Muscarinic regulation of Alzheimer's disease amyloid precursor protein secretion and amyloid beta-protein production in human neuronal NT2N cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Production of Alzheimer 4kDa beta-amyloid peptide requires the C-terminal cytosolic domain of the amyloid precursor protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced release of amyloid beta-protein from codon 670/671 "Swedish" mutant beta-amyloid precursor protein occurs in both secretory and endocytic pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid precursor protein processing is stimulated by metabotropic glutamate receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of protein kinase C inhibits cellular production of the amyloid beta-protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-Amyloid induces neuritic dystrophy in vitro: similarities with Alzheimer pathology

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human neurons derived from a teratocarcinoma cell line express solely the 695-amino acid amyloid precursor protein and produce intracellular beta-amyloid or A4 peptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloidogenic processing of the human amyloid precursor protein in primary cultures of rat hippocampal neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that production and release of amyloid beta-protein involves the endocytic pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of beta-amyloid production by activation of protein kinase C.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C and tumor promoters

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secretory processing of the Alzheimer amyloid beta/A4 protein precursor is increased by protein phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta peptide of Alzheimer's disease downregulates Bcl-2 and upregulates bax expression in human neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased production of 4 kDa amyloid beta peptide in serum deprived human primary neuron cultures: possible involvement of apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cholinergic agonists and interleukin 1 regulate processing and secretion of the Alzheimer beta/A4 amyloid protein precursor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The release of Alzheimer's disease beta amyloid peptide is reduced by phorbol treatment.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Swedish mutation causes early-onset Alzheimer's disease by beta-secretase cleavage within the secretory pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the beta-amyloid precursor protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of cholinesterase inhibitors on the secretion of APPS from rat brain cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Soluble derivatives of the beta amyloid protein precursor of Alzheimer's disease are labeled by antisera to the beta amyloid protein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Production of the Alzheimer amyloid beta protein by normal proteolytic processing

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis mediated neurotoxicity induced by chronic application of beta amyloid fragment 25-35.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid precursor protein secretion and beta A4 amyloid generation are not mutually exclusive

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid precursor protein metabolism in primary cell cultures of neurons, astrocytes, and microglia

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulated formation of Golgi secretory vesicles containing Alzheimer beta-amyloid precursor protein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potentially Amyloidogenic, Carboxyl-Terminal Derivatives of the Amyloid Protein Precursor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta-peptide is produced by cultured cells during normal metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulated secretion of beta-amyloid precursor protein in rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human fetal extremity lengths in the interval from 9 to 21 menstrual weeks of pregnancy

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium regulates processing of the Alzheimer amyloid protein precursor in a protein kinase C-independent manner

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism of the "Swedish" amyloid precursor protein variant in neuro2a (N2a) cells. Evidence that cleavage at the "beta-secretase" site occurs in the golgi apparatus

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease: genotypes, phenotypes, and treatments

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generation of beta-amyloid in the secretory pathway in neuronal and nonneuronal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin 1 regulates synthesis of amyloid beta-protein precursor mRNA in human endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein phosphorylation regulates secretion of Alzheimer beta/A4 amyloid precursor protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Processing of the Amyloid Protein Precursor to Potentially Amyloidogenic Derivatives

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-Amyloid peptide and a 3-kDa fragment are derived by distinct cellular mechanisms.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serotonin 5-HT2a and 5-HT2c receptors stimulate amyloid precursor protein ectodomain secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Processing of amyloid precursor protein in human primary neuron and astrocyte cultures.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9526007

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.18-08-02907.1998

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792603&resulttype=core&format=json

12 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792603&resulttype=core&format=json

12 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792603&resulttype=core&format=json

12 May 2020

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q48487209&oldid=1389901151"