(Q48489003)

12 February 2018

title

Prediction of clearance in humans from in vitro human liver microsomes and allometric scaling. A comparative study of the two approaches. (English)

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12 February 2018

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Iftekhar Mahmood

1

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12 February 2018

publication date

1 January 2002

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12 February 2018

Drug Metabolism and Drug Interactions

published in

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12 February 2018

volume

19

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12 February 2018

page(s)

49-64

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12 February 2018

issue

1

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12 February 2018

https://api.crossref.org/works/10.1515%2FDMDI.2002.19.1.49

1 reference

Interspecies scaling: predicting pharmacokinetic parameters of antiepileptic drugs in humans from animals with special emphasis on clearance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2002.19.1.49

Interspecies scaling: predicting clearance of drugs in humans. Three different approaches

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2002.19.1.49

Interspecies pharmacokinetic scaling and the evolutionary-comparative paradigm

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2002.19.1.49

Scaling of antipyrine intrinsic clearance of unbound drug in 15 mammalian species.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2002.19.1.49

Integration of in vitro data into allometric scaling to predict hepatic metabolic clearance in man: application to 10 extensively metabolized drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2002.19.1.49

Integration of in vitro data and brain weight in allometric scaling to predict clearance in humans: some suggestions

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2002.19.1.49

Prediction of in vivo drug metabolism in the human liver from in vitro metabolism data

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2002.19.1.49

Utility of in vitro drug metabolism data in predicting in vivo metabolic clearance

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2002.19.1.49

Predicting toxicokinetic parameters in humans from toxicokinetic data acquired from three small mammalian species

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2002.19.1.49

The pharmacokinetics and organ distribution of ajmaline and quindine in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2002.19.1.49

Prediction of the disposition of nine weakly acidic and six weakly basic drugs in humans from pharmacokinetic parameters in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2002.19.1.49

Prediction of the disposition of propafenone in humans and dogs from pharmacokinetic parameters in other animal species.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2002.19.1.49

Identification of the cytochrome P450 enzymes involved in the N-demethylation of sildenafil

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2002.19.1.49

Interspecies scaling of cimetidine-theophylline pharmacokinetic interaction: interspecies scaling in pharmacokinetic interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2002.19.1.49

Clinical pharmacokinetics of troglitazone

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2002.19.1.49

An electrically modulated drug delivery device. III. Factors affecting drug stability during electrophoresis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2002.19.1.49

Clinical pharmacokinetics of tacrolimus

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2002.19.1.49

Interspecies scaling: is a priori knowledge of cytochrome p450 isozymes involved in drug metabolism helpful in prediction of clearance in humans from animal data?

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2002.19.1.49

In vitro characterization of the human cytochrome P-450 involved in polymorphic oxidation of propafenone

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2002.19.1.49

Metabolism of FK506, a potent immunosuppressive agent, by cytochrome P450 3A enzymes in rat, dog and human liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2002.19.1.49

10.1515/DMDI.2002.19.1.49

21 January 2018

Identifiers

DOI

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12 February 2018

PubMed ID

12222754

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12 February 2018