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Chronic gliosis triggers Alzheimer's disease-like processing of amyloid precursor protein.
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1 reference
stated in
Europe PubMed Central
PubMed ID
12182886
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12182886%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
title
Chronic gliosis triggers Alzheimer's disease-like processing of amyloid precursor protein
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
12182886
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12182886%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
main subject
Alzheimer's disease
0 references
author
Ralph Martins
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed ID
12182886
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12182886%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
author name string
K A Bates
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
12182886
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12182886%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
J Fonte
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
12182886
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12182886%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
T A Robertson
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed ID
12182886
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12182886%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
A R Harvey
series ordinal
5
1 reference
stated in
Europe PubMed Central
PubMed ID
12182886
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12182886%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
language of work or name
English
0 references
publication date
1 January 2002
1 reference
stated in
Europe PubMed Central
PubMed ID
12182886
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12182886%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
published in
Neuroscience
1 reference
stated in
Europe PubMed Central
PubMed ID
12182886
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12182886%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
volume
113
1 reference
stated in
Europe PubMed Central
PubMed ID
12182886
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12182886%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
issue
4
1 reference
stated in
Europe PubMed Central
PubMed ID
12182886
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12182886%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
page(s)
785-796
1 reference
stated in
Europe PubMed Central
PubMed ID
12182886
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12182886%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
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Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system
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1 reference
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7 January 2021
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Perlecan binds to the beta-amyloid proteins (A beta) of Alzheimer's disease, accelerates A beta fibril formation, and maintains A beta fibril stability.
1 reference
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7 January 2021
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Oxidative stress and Alzheimer disease
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7 January 2021
based on heuristic
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Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families
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7 January 2021
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Cellular forms and functions of brain microglia
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7 January 2021
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Association of an interleukin 1 alpha polymorphism with Alzheimer's disease
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Crossref
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7 January 2021
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Amyloidogenicity of rodent and human beta A4 sequences.
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7 January 2021
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Molecular profile of reactive astrocytes--implications for their role in neurologic disease
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7 January 2021
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Prospects for pharmacological intervention in Alzheimer disease
1 reference
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Crossref
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7 January 2021
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inferred from DOI database lookup
Molecular pathology of head trauma: altered beta APP metabolism and the aetiology of Alzheimer's disease.
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7 January 2021
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Aging renders the brain vulnerable to amyloid beta-protein neurotoxicity
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7 January 2021
based on heuristic
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Microglia and the immune pathology of Alzheimer disease
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease
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Crossref
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https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Head injury and the risk of AD in the MIRAGE study
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
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7 January 2021
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inferred from DOI database lookup
The status and organization of astrocytes, oligodendroglia and microglia in grafts of fetal rat cerebral cortex.
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Chronic neuroinflammation in rats reproduces components of the neurobiology of Alzheimer's disease
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
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7 January 2021
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inferred from DOI database lookup
Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
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7 January 2021
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inferred from DOI database lookup
Rheumatoid arthritis and senile dementia of the Alzheimer's type.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Two novel (M233T and R278T) presenilin-1 mutations in early-onset Alzheimer's disease pedigrees and preliminary evidence for association of presenilin-1 mutations with a novel phenotype.
1 reference
stated in
Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
The -491AA polymorphism in the APOE gene is associated with increased plasma apoE levels in Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
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7 January 2021
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inferred from DOI database lookup
Gene-expression profile of the ageing brain in mice
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Crossref
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7 January 2021
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Exploring the etiology of Alzheimer disease using molecular genetics
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E and alpha-1-antichymotrypsin allele polymorphism in sporadic and familial Alzheimer's disease.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
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7 January 2021
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inferred from DOI database lookup
Nonsteroidal antiinflammatory drug use in Alzheimer's disease.
1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Altered expression of apolipoprotein E, amyloid precursor protein and presenilin-1 is associated with chronic reactive gliosis in rat cortical tissue.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Anti‐inflammatory agents as a therapeutic approach to Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Specific downregulation of presenilin 2 gene expression is prominent during early stages of sporadic late-onset Alzheimer's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alzheimer's disease and rheumatoid arthritis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of APP cleavage by alpha-, beta- and gamma-secretases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Reactive microglia in aging and dementia: an immunohistochemical study of postmortem human brain tissue.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of the chondroitin sulfate proteoglycans of amyloid precursor (appican) and amyloid precursor-like protein 2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Early association of reactive astrocytes with senile plaques in Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apolipoprotein E in sporadic Alzheimer's disease: allelic variation and receptor interactions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential effects of transforming growth factor-beta(s) and glial cell line-derived neurotrophic factor on gene expression of presenilin-1 in human post-mitotic neurons and astrocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Enhancement of beta-amyloid precursor protein transcription and expression by the soluble interleukin-6 receptor/interleukin-6 complex.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Beta amyloid protein deposition in the brain after severe head injury: implications for the pathogenesis of Alzheimer's disease
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Translation of the alzheimer amyloid precursor protein mRNA is up-regulated by interleukin-1 through 5'-untranslated region sequences.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Amyloid precursor protein proteoglycan is increased after brain damage.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Constitutive and cytokine-regulated expression of presenilin-1 and presenilin-2 genes in human neural cell lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alpha-1-antichymotrypsin gene polymorphism and risk for sporadic Alzheimer's disease in a German population
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induced expression of neuronal membrane attack complex and cell death by Alzheimer's beta-amyloid peptide
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Alzheimer amyloid precursor proteoglycan (appican) is present in brain and is produced by astrocytes but not by neurons in primary neural cultures.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An important role of heparan sulfate proteoglycan (Perlecan) in a model system for the deposition and persistence of fibrillar A beta-amyloid in rat brain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Temporal accrual of complement proteins in amyloid plaques in Down's syndrome with Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The amyloid precursor protein of Alzheimer's disease and the Abeta peptide.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Astrocytes, oligodendroglia, extracellular space volume and geometry in rat fetal brain grafts.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of presenilin-1 and -2 mRNAs in rat and Alzheimer's disease brains.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Frameshift mutants of beta amyloid precursor protein and ubiquitin-B in Alzheimer's and Down patients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytokines associated with amyloid plaques in Alzheimer's disease brain stimulate human glial and neuronal cell cultures to secrete early complement proteins, but not C1-inhibitor.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibiting amyloid precursor protein C-terminal cleavage promotes an interaction with presenilin 1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of estradiol on neuronal Swedish-mutated beta-amyloid precursor protein metabolism: reversal by astrocytic cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Estrogen use, APOE, and cognitive decline: evidence of gene-environment interaction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Metalloendopeptidase EC 3.4.24.15 is necessary for Alzheimer's amyloid-beta peptide degradation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Up-regulated production and activation of the complement system in Alzheimer's disease brain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-4522%2802%2900230-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0306-4522(02)00230-0
1 reference
stated in
Europe PubMed Central
PubMed ID
12182886
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12182886%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
Fatcat ID
release_hkm37q3vdvbwpcf7wmbkcpjeby
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/hkm37q3vdvbwpcf7wmbkcpjeby
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
PubMed ID
12182886
1 reference
stated in
Europe PubMed Central
PubMed ID
12182886
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12182886%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
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