(Q53341926)

13 May 2018

title

Specific downregulation of presenilin 2 gene expression is prominent during early stages of sporadic late-onset Alzheimer's disease. (English)

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13 May 2018

author

James B Leverenz

series ordinal

2

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13 May 2018

author name string

McMillan PJ

series ordinal

1

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13 May 2018

Dorsa DM

series ordinal

3

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13 May 2018

publication date

1 May 2000

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13 May 2018

published in

Molecular Brain Research

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13 May 2018

volume

78

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13 May 2018

issue

1-2

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13 May 2018

page(s)

138-145

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13 May 2018

Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

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Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency

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7 January 2021

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7 January 2021

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

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7 January 2021

Presenilin 1 is required for Notch1 and DII1 expression in the paraxial mesoderm

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7 January 2021

10.1016/S0169-328X(00)00086-3

Identifiers

DOI

1 reference

13 May 2018

PubMed ID

10891593

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13 May 2018