(Q48526952)

12 February 2018

title

Production of beta-amyloid by primary human foetal mixed brain cell cultures and its modulation by exogenous soluble beta-amyloid (English)

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12 February 2018

author name string

Hayes GM

series ordinal

1

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12 February 2018

Howlett DR

series ordinal

2

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12 February 2018

Griffin GE

series ordinal

3

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12 February 2018

language of work or name

English

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publication date

1 January 2002

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12 February 2018

published in

Neuroscience

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12 February 2018

volume

113

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12 February 2018

issue

3

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12 February 2018

page(s)

641-646

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12 February 2018

Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation.

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Flemish and Dutch mutations in amyloid beta precursor protein have different effects on amyloid beta secretion

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Models of amyloid seeding in Alzheimer's disease and scrapie: mechanistic truths and physiological consequences of the time-dependent solubility of amyloid proteins

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Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons.

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Human rotation-mediated fetal mixed brain cell aggregate culture: characterization and N-methyl-D-aspartate toxicity

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Analysis of heterogeneous A4 peptides in human cerebrospinal fluid and blood by a newly developed sensitive Western blot assay.

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Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43).

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Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

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Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red.

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Quantification of glial fibrillary acidic protein: comparison of slot-immunobinding assays with a novel sandwich ELISA.

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Oligomerization of endogenous and synthetic amyloid beta-protein at nanomolar levels in cell culture and stabilization of monomer by Congo red.

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Normal and abnormal biology of the beta-amyloid precursor protein

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Detection of a novel intraneuronal pool of insoluble amyloid beta protein that accumulates with time in culture

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An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

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7 January 2021

Amyloids beta40 and beta42 are generated intracellularly in cultured human neurons and their secretion increases with maturation

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7 January 2021

The oligomerization of amyloid beta-protein begins intracellularly in cells derived from human brain

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7 January 2021

Fractionation and characterization of oligomeric, protofibrillar and fibrillar forms of beta-amyloid peptide

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7 January 2021

Intracellular generation and accumulation of amyloid beta-peptide terminating at amino acid 42.

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7 January 2021

Seeding of A beta fibril formation is inhibited by all three isotypes of apolipoprotein E.

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7 January 2021

Enhanced production and oligomerization of the 42-residue amyloid beta-protein by Chinese hamster ovary cells stably expressing mutant presenilins

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7 January 2021

Intracellular accumulation of insoluble, newly synthesized abetan-42 in amyloid precursor protein-transfected cells that have been treated with Abeta1-42.

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7 January 2021

10.1016/S0306-4522(02)00191-4

Identifiers

DOI

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12 February 2018

1 reference

12 February 2018