(Q48541886)

12 February 2018

title

AIRE's CARD revealed, a new structure for central tolerance provokes transcriptional plasticity (English)

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12 February 2018

author

Pärt Peterson

9

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12 February 2018

Brian J Ferguson

Brian J Ferguson

1

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Ana Rebane

Ana Rebane

5

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Graham Anderson

Graham Anderson

11

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Hamish S. Scott

Hamish S Scott

12

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Simona Rossi Girard

Simona W Rossi

3

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Catherine Louise Worth

6

Catherine L Worth

1 reference

12 February 2018

Ingrid Liiv

4

Ingrid Liiv

1 reference

12 February 2018

Tina Rich

14

Tina Rich

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12 February 2018

author name string

Clare Alexander

2

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12 February 2018

Joyce Wong

7

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12 February 2018

Martti Laan

8

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12 February 2018

Eric J Jenkinson

10

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12 February 2018

Anne Cooke

13

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12 February 2018

language of work or name

English

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publication date

1 November 2007

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12 February 2018

Journal of Biological Chemistry

published in

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12 February 2018

volume

283

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12 February 2018

issue

3

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12 February 2018

page(s)

1723-1731

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12 February 2018

Good riddance: Thymocyte clonal deletion prevents autoimmunity

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An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains

21 January 2018

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Projection of an immunological self shadow within the thymus by the aire protein

21 January 2018

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Chromosomal clustering of genes controlled by the aire transcription factor

21 January 2018

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Loss of Aire-dependent thymic expression of a peripheral tissue antigen renders it a target of autoimmunity

21 January 2018

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Spontaneous autoimmunity prevented by thymic expression of a single self-antigen

21 January 2018

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Highly variable expression of tissue-restricted self-antigens in human thymus: implications for self-tolerance and autoimmunity.

21 January 2018

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APECED-causing mutations in AIRE reveal the functional domains of the protein

21 January 2018

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Review: properties and assembly mechanisms of ND10, PML bodies, or PODs

21 January 2018

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FUGUE: sequence-structure homology recognition using environment-specific substitution tables and structure-dependent gap penalties

21 January 2018

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The autoimmune regulator protein has transcriptional transactivating properties and interacts with the common coactivator CREB-binding protein

21 January 2018

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Cooperative activation of transcription by autoimmune regulator AIRE and CBP.

21 January 2018

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Subcellular expression of autoimmune regulator is organized in a spatiotemporal manner

21 January 2018

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RANK signals from CD4(+)3(-) inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla

21 January 2018

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Comparative protein structure modeling of genes and genomes

21 January 2018

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Main-chain bond lengths and bond angles in protein structures

21 January 2018

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WHAT IF: a molecular modeling and drug design program

21 January 2018

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Assessment of protein models with three-dimensional profiles

21 January 2018

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Prediction of the stability of protein mutants based on structural environment-dependent amino acid substitution and propensity tables

21 January 2018

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Autoimmune regulator is expressed in the cells regulating immune tolerance in thymus medulla.

21 January 2018

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Evidence for the receipt of DNA damage stimuli by PML nuclear domains

21 January 2018

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21 January 2018

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Nuclear dots: actors on many stages

21 January 2018

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The nuclear dot protein sp100, characterization of domains necessary for dimerization, subcellular localization, and modification by small ubiquitin-like modifiers

21 January 2018

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Systematic mutagenesis of the functional domains of AIRE reveals their role in intracellular targeting

21 January 2018

1 reference

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A highly amplified mouse gene is homologous to the human interferon-responsive Sp100 gene encoding an autoantigen associated with nuclear dots

21 January 2018

1 reference

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Flexible nets. The roles of intrinsic disorder in protein interaction networks.

21 January 2018

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The death domain superfamily in intracellular signaling of apoptosis and inflammation

21 January 2018

1 reference

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Subcellular localization of the autoimmune regulator protein. characterization of nuclear targeting and transcriptional activation domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707211200

Death-effector filaments: novel cytoplasmic structures that recruit caspases and trigger apoptosis

21 January 2018

1 reference

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Lymphotoxin pathway directs thymic Aire expression

21 January 2018

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Distribution of co-activators CBP and p300 during mouse oocyte and embryo development.

21 January 2018

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The natural history of protein domains

21 January 2018

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Inflammasome adaptors and sensors: intracellular regulators of infection and inflammation

21 January 2018

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Death Domain Assembly Mechanism Revealed by Crystal Structure of the Oligomeric PIDDosome Core Complex

21 January 2018

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Association of caspase-2 with the promyelocytic leukemia protein nuclear bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707211200

FLASH links the CD95 signaling pathway to the cell nucleus and nuclear bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707211200

Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707211200

Differential role of Sp100 isoforms in interferon-mediated repression of herpes simplex virus type 1 immediate-early protein expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707211200

RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707211200

The osteoclast differentiation factor osteoprotegerin-ligand is essential for mammary gland development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707211200

Medullary thymic epithelial cells expressing Aire represent a unique lineage derived from cells expressing claudin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707211200

PML is essential for multiple apoptotic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707211200

The transcriptional regulator CBP has defined spatial associations within interphase nuclei.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707211200

The IkappaB function of NF-kappaB2 p100 controls stimulated osteoclastogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707211200

NF-kappaB2 is required for the establishment of central tolerance through an Aire-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707211200

21 January 2018

Identifiers

DOI

10.1074/JBC.M707211200

1 reference

12 February 2018

1 reference

12 February 2018