(Q48557527)

12 February 2018

title

Abeta 42-induced increase in neprilysin is associated with prevention of amyloid plaque formation in vivo (English)

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12 February 2018

author name string

M Hasan Mohajeri

series ordinal

1

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12 February 2018

M Axel Wollmer

series ordinal

2

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12 February 2018

Roger M Nitsch

series ordinal

3

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12 February 2018

language of work or name

English

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publication date

8 July 2002

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12 February 2018

Journal of Biological Chemistry

published in

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12 February 2018

volume

277

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12 February 2018

issue

38

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12 February 2018

page(s)

35460-35465

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12 February 2018

Identification of the major Abeta1-42-degrading catabolic pathway in brain parenchyma: suppression leads to biochemical and pathological deposition

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Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

21 January 2018

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Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

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Additive effects of PS1 and APP mutations on secretion of the 42-residue amyloid beta-protein.

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Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

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Does Alzheimer disease tilt the scales of amyloid degradation versus accumulation?

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Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

21 January 2018

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Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

21 January 2018

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Metalloendopeptidase EC 3.4.24.15 is necessary for Alzheimer's amyloid-beta peptide degradation

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Neutral endopeptidase modulation of septic shock.

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Neutral endopeptidase modulates septic shock

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Characterization of the promoter region of the rat neprilysin gene

21 January 2018

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21 January 2018

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Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

21 January 2018

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Neprilysin degrades both amyloid beta peptides 1-40 and 1-42 most rapidly and efficiently among thiorphan- and phosphoramidon-sensitive endopeptidases

21 January 2018

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Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation

21 January 2018

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Angiotensin converting enzyme and endothelial nitric oxide synthase DNA polymorphisms and late onset Alzheimer's disease

21 January 2018

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The renin angiotensin system and Alzheimer's disease.

21 January 2018

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Angiotensin converting enzyme density is increased in temporal cortex from patients with Alzheimer's disease

21 January 2018

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Degradation of Alzheimer's beta-amyloid protein by human and rat brain peptidases: involvement of insulin-degrading enzyme.

21 January 2018

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Seeding "one-dimensional crystallization" of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie?

21 January 2018

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Characterization of tynorphin, a potent endogenous inhibitor of dipeptidyl peptidaseIII.

21 January 2018

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Glycoprotein 330/megalin: probable role in receptor-mediated transport of apolipoprotein J alone and in a complex with Alzheimer disease amyloid beta at the blood-brain and blood-cerebrospinal fluid barriers

21 January 2018

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Human blood-brain barrier receptors for Alzheimer's amyloid-beta 1- 40. Asymmetrical binding, endocytosis, and transcytosis at the apical side of brain microvascular endothelial cell monolayer

21 January 2018

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Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease

21 January 2018

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Metabolic regulation of brain Abeta by neprilysin.

21 January 2018

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Clearance of extracellular and cell-associated amyloid beta peptide through viral expression of neprilysin in primary neurons

21 January 2018

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Regional expression of Bcl-2 mRNA and mitochondrial cytochrome c release after experimental brain injury in the rat.

21 January 2018

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Immunohistochemical localization of neprilysin in the human cerebral cortex: inverse association with vulnerability to amyloid beta-protein (Abeta) deposition

21 January 2018

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Relationship between beta amyloid peptide generating molecules and neprilysin in Alzheimer disease and normal brain

21 January 2018

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Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

21 January 2018

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Temporal and spatial profile of caspase 8 expression and proteolysis after experimental traumatic brain injury

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M202899200

1 reference

12 February 2018

1 reference

12 February 2018