(Q48559530)

English

Transforming growth factor-beta-induced transcription of the Alzheimer beta-amyloid precursor protein gene involves interaction between the CTCF-complex and Smads.

scientific article published in July 2002

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scholarly article

1 reference

Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/12099698

Transforming growth factor-beta-induced transcription of the Alzheimer beta-amyloid precursor protein gene involves interaction between the CTCF-complex and Smads. (English)

1 reference

Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/12099698

Alzheimer's disease

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author name string

Teralee Burton

1

1 reference

Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/12099698

Binhua Liang

2

1 reference

Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/12099698

Alex Dibrov

3

1 reference

Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/12099698

Francis Amara

4

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Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/12099698

language of work or name

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publication date

1 July 2002

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Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/12099698

Biochemical and Biophysical Research Communications

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Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/12099698

295

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Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/12099698

713-723

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Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/12099698

3

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Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/12099698

In situ hybridization of nucleus basalis neurons shows increased beta-amyloid mRNA in Alzheimer disease

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Relation of neuronal APP-751/APP-695 mRNA ratio and neuritic plaque density in Alzheimer's disease

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Expression of the Alzheimer amyloid precursor gene transcripts in the human brain.

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Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

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USF binds to the APB alpha sequence in the promoter of the amyloid beta-protein precursor gene

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7 January 2021

The zinc finger protein CTCF binds to the APBbeta domain of the amyloid beta-protein precursor promoter. Evidence for a role in transcriptional activation

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7 January 2021

Regulation of beta-amyloid precursor protein isoform mRNAs by transforming growth factor-beta 1 and interleukin-1 beta in astrocytes.

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Transforming growth factor-beta 1 is in plaques in Alzheimer and Down pathologies.

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Cellular signaling roles of TGF beta, TNF alpha and beta APP in brain injury responses and Alzheimer's disease

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Amyloidogenic role of cytokine TGF-beta1 in transgenic mice and in Alzheimer's disease

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TGF-beta(1), regulation of alzheimer amyloid precursor protein mRNA expression in a normal human astrocyte cell line: mRNA stabilization

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Transforming growth factor beta mediates increase of mature transmembrane amyloid precursor protein in microglial cells

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Extracellular matrix influences the biogenesis of amyloid precursor protein in microglial cells

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Relationship of microglia and astrocytes to amyloid deposits of Alzheimer disease.

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Transforming growth factor-betas in neurodegenerative disease

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7 January 2021

Mads and Smads in TGF beta signalling

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The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms

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TGF-beta signal transduction

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7 January 2021

TGF-beta-receptor-mediated signaling

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7 January 2021

TGF beta signals through a heteromeric protein kinase receptor complex

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7 January 2021

Caenorhabditis elegans genes sma-2, sma-3, and sma-4 define a conserved family of transforming growth factor beta pathway components

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7 January 2021

Transforming growth factor beta-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells

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7 January 2021

MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling

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7 January 2021

Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways.

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7 January 2021

TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4

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7 January 2021

TGF-beta signalling from cell membrane to nucleus through SMAD proteins

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7 January 2021

Smad4 and FAST-1 in the assembly of activin-responsive factor

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7 January 2021

Involvement of Smads in TGFbeta1-induced furin (fur) transcription

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7 January 2021

Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription

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7 January 2021

A human Mad protein acting as a BMP-regulated transcriptional activator

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7 January 2021

Physical and functional interaction of SMADs and p300/CBP

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7 January 2021

Transcription factor NF-kappaB is activated in primary neurons by amyloid beta peptides and in neurons surrounding early plaques from patients with Alzheimer disease

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7 January 2021

Elastase release of basic fibroblast growth factor in pulmonary fibroblast cultures results in down-regulation of elastin gene transcription. A role for basic fibroblast growth factor in regulating lung repair

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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Is amyloidogenesis during Alzheimer's disease due to an IL-1-/IL-6-mediated 'acute phase response' in the brain?

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Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes

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Overlapping binding sites of two different transcription factors in the promoter of the human gene for the Alzheimer amyloid precursor protein.

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7 January 2021

The initiator element and proximal upstream sequences affect transcriptional activity and start site selection in the amyloid beta-protein precursor promoter

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CTCF is essential for up-regulating expression from the amyloid precursor protein promoter during differentiation of primary hippocampal neurons

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Differential effect of zinc finger deletions on the binding of CTCF to the promoter of the amyloid precursor protein gene

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A region to the N-terminal side of the CTCF zinc finger domain is essential for activating transcription from the amyloid precursor protein promoter

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Differential expression and phosphorylation of CTCF, a c-myc transcriptional regulator, during differentiation of human myeloid cells

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Functional phosphorylation sites in the C-terminal region of the multivalent multifunctional transcriptional factor CTCF

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Chronic overproduction of transforming growth factor-beta1 by astrocytes promotes Alzheimer's disease-like microvascular degeneration in transgenic mice

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Identifiers

10.1016/S0006-291X(02)00725-8

1 reference

Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/12099698

1 reference

Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/12099698

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