(Q48567917)

http://europepmc.org/abstract/MED/9390997

12 February 2018

title

Regulation of amyloid precursor protein catabolism involves the mitogen-activated protein kinase signal transduction pathway. (English)

1 reference

http://europepmc.org/abstract/MED/9390997

12 February 2018

author name string

J Mills

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6573401&resulttype=core&format=json

15 May 2020

D Laurent Charest

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6573401&resulttype=core&format=json

15 May 2020

F Lam

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6573401&resulttype=core&format=json

15 May 2020

K Beyreuther

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6573401&resulttype=core&format=json

15 May 2020

N Ida

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6573401&resulttype=core&format=json

15 May 2020

S L Pelech

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6573401&resulttype=core&format=json

15 May 2020

P B Reiner

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6573401&resulttype=core&format=json

15 May 2020

language of work or name

English

0 references

publication date

1 December 1997

1 reference

http://europepmc.org/abstract/MED/9390997

12 February 2018

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6573401&resulttype=core&format=json

15 May 2020

volume

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6573401&resulttype=core&format=json

15 May 2020

issue

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6573401&resulttype=core&format=json

15 May 2020

page(s)

9415-9422

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6573401&resulttype=core&format=json

Tyrosine phosphorylation-dependent stimulation of amyloid precursor protein secretion by the m3 muscarinic acetylcholine receptor

15 May 2020

cites work

1 reference

12 December 2020

Expression of a ubiquitous, cross-reactive homologue of the mouse beta-amyloid precursor protein (APP).

1 reference

12 December 2020

Selective ectodomain phosphorylation and regulated cleavage of beta-amyloid precursor protein

1 reference

12 December 2020

Inhibition of MAP Kinase Kinase Blocks the Differentiation of PC-12 Cells Induced by Nerve Growth Factor

1 reference

12 December 2020

Amino-terminal region of the beta-amyloid precursor protein activates mitogen-activated protein kinase

1 reference

12 December 2020

Membrane proteins with soluble counterparts: role of proteolysis in the release of transmembrane proteins

1 reference

12 December 2020

Muscarinic regulation of Alzheimer's disease amyloid precursor protein secretion and amyloid beta-protein production in human neuronal NT2N cells

1 reference

12 December 2020

Estrogen regulates metabolism of Alzheimer amyloid beta precursor protein

1 reference

12 December 2020

Ectodomain phosphorylation of beta-amyloid precursor protein at two distinct cellular locations

1 reference

12 December 2020

Amyloid precursor protein processing is stimulated by metabotropic glutamate receptors

1 reference

12 December 2020

Activation of protein kinase C inhibits cellular production of the amyloid beta-protein

1 reference

12 December 2020

Transforming growth factor-alpha and beta-amyloid precursor protein share a secretory mechanism.

1 reference

12 December 2020

Identification of TrkB autophosphorylation sites and evidence that phospholipase C-gamma 1 is a substrate of the TrkB receptor

1 reference

12 December 2020

A synthetic inhibitor of the mitogen-activated protein kinase cascade

1 reference

12 December 2020

Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

1 reference

12 December 2020

Nerve growth factor-induced neuronal differentiation is accompanied by differential induction and localization of the amyloid precursor protein (APP) in PC12 cells and variant PC12S cells.

1 reference

12 December 2020

Cellular signaling roles of TGF beta, TNF alpha and beta APP in brain injury responses and Alzheimer's disease

1 reference

12 December 2020

Phorbol esters but not the cholinergic agonists oxotremorine-M and carbachol increase release of the amyloid precursor protein in cultured rat cortical neurons.

1 reference

12 December 2020

Inhibition of beta-amyloid production by activation of protein kinase C.

1 reference

12 December 2020

Protein kinase C activity is rate limiting for shedding of the interleukin-6 receptor.

1 reference

12 December 2020

Metabolism of Alzheimer beta-amyloid precursor protein: regulation by protein kinase A in intact cells and in a cell-free system

1 reference

12 December 2020

Regulation of APP processing. Potential for the therapeutical reduction of brain amyloid burden

1 reference

12 December 2020

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

1 reference

12 December 2020

How MAP kinases are regulated

1 reference

12 December 2020

Tyrosine kinases are required for catecholamine secretion and mitogen-activated protein kinase activation in bovine adrenal chromaffin cells.

1 reference

12 December 2020

Secreted beta-amyloid precursor protein stimulates mitogen-activated protein kinase and enhances tau phosphorylation.

1 reference

12 December 2020

The regulation of amyloid beta protein precursor secretion and its modulatory role in cell adhesion

1 reference

12 December 2020

Calcium ionophore increases amyloid beta peptide production by cultured cells

1 reference

12 December 2020

Beta-amyloid precursor protein of Alzheimer disease occurs as 110- to 135-kilodalton membrane-associated proteins in neural and nonneural tissues.

1 reference

12 December 2020

Multiple signals activate cleavage of the membrane transforming growth factor-alpha precursor

1 reference

12 December 2020

Electroconvulsive Treatment Induces a Rapid and Transient Increase in Tyrosine Phosphorylatin of a 40-Kilodalton Protein Associated with Microtubule-Associated Protein 2 Kinase Activity

1 reference

12 December 2020

Mitogen-activated protein kinase kinase inhibition does not block the stimulation of glucose utilization by insulin

1 reference

12 December 2020

Cholinergic agonists and interleukin 1 regulate processing and secretion of the Alzheimer beta/A4 amyloid protein precursor

1 reference

12 December 2020

The release of Alzheimer's disease beta amyloid peptide is reduced by phorbol treatment.

1 reference

12 December 2020

Activation of p42 mitogen-activated protein kinase by glutamate receptor stimulation in rat primary cortical cultures

1 reference

12 December 2020

Phosphoinositide turnover associated with synaptic transmission

1 reference

12 December 2020

High-efficiency transformation of mammalian cells by plasmid DNA

1 reference

12 December 2020

Regulation of APP expression, biogenesis and metabolism by extracellular matrix and cytokines.

1 reference

12 December 2020

Requirements for Phosphorylation of Map Kinase During Meiosis in Xenopus Oocytes

1 reference

12 December 2020

Processing of Alzheimer beta/A4 amyloid precursor protein: modulation by agents that regulate protein phosphorylation

1 reference

12 December 2020

Formation of stable complexes between two Alzheimer's disease gene products: presenilin-2 and beta-amyloid precursor protein

1 reference

12 December 2020

Glucose, other secretagogues, and nerve growth factor stimulate mitogen-activated protein kinase in the insulin-secreting beta-cell line, INS-1.

1 reference

12 December 2020

Production of the Alzheimer amyloid beta protein by normal proteolytic processing

1 reference

12 December 2020

Protein serine/threonine kinases of the MAPK cascade

1 reference

12 December 2020

Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice

1 reference

12 December 2020

Identification of the regulatory phosphorylation sites in pp42/mitogen-activated protein kinase (MAP kinase)

1 reference

12 December 2020

Ligand and protein kinase C downmodulate the colony-stimulating factor 1 receptor by independent mechanisms

1 reference

12 December 2020

Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors

1 reference

12 December 2020

Requirement for integration of signals from two distinct phosphorylation pathways for activation of MAP kinase

1 reference

12 December 2020

Evidence for phosphorylation and oligomeric assembly of presenilin 1.

1 reference

12 December 2020

The E280A presenilin 1 Alzheimer mutation produces increased A beta 42 deposition and severe cerebellar pathology.

1 reference

12 December 2020

Exact cleavage site of Alzheimer amyloid precursor in neuronal PC-12 cells

1 reference

12 December 2020

Increased activity-regulating and neuroprotective efficacy of alpha-secretase-derived secreted amyloid precursor protein conferred by a C-terminal heparin-binding domain

1 reference

12 December 2020

Proteolytic processing of the Alzheimer disease-associated presenilin-1 generates an in vivo substrate for protein kinase C.

1 reference

12 December 2020

MAP kinases: charting the regulatory pathways

1 reference

12 December 2020

A conserved motif at the amino termini of MEKs might mediate high-affinity interaction with the cognate MAPKs

1 reference

12 December 2020

Proteolytic processing of a plasma membrane-bound precursor to human macrophage colony-stimulating factor (CSF-1) is accelerated by phorbol ester

1 reference

12 December 2020

Networking with mitogen-activated protein kinases.

1 reference

12 December 2020

Analysis of heterogeneous A4 peptides in human cerebrospinal fluid and blood by a newly developed sensitive Western blot assay.

1 reference

12 December 2020

Electrophoretic Separation of βA4 Peptides (1–40) and (1–42)

1 reference

12 December 2020

Activation of mitogen-activating protein kinase by glucose is not required for insulin secretion

1 reference

12 December 2020

Protein phosphorylation inhibits production of Alzheimer amyloid beta/A4 peptide

1 reference

12 December 2020

Role of neurotransmission in the regulation of amyloid beta-protein precursor processing

1 reference

12 December 2020

Glutamate receptor ion channel properties predict vulnerability to cytotoxicity in a transfected nonneuronal cell line

1 reference

12 December 2020

The regulation of tyrosine kinase signalling pathways by growth factor and G-protein-coupled receptors.

1 reference

12 December 2020

Evidence that beta-amyloid protein in Alzheimer's disease is not derived by normal processing

1 reference

12 December 2020

Overexpression of mitogen-activated protein kinase kinase (MAPKK) and its mutants in NIH 3T3 cells. Evidence that MAPKK involvement in cellular proliferation is regulated by phosphorylation of serine residues in its kinase subdomains VII and VIII

1 reference

12 December 2020

Amyloid beta-peptide is produced by cultured cells during normal metabolism

1 reference

12 December 2020

In vitro phosphorylation of the cytoplasmic domain of the amyloid precursor protein by glycogen synthase kinase-3beta

1 reference

12 December 2020

Amyloid, the presenilins and Alzheimer's disease

1 reference

12 December 2020

Regulated secretion of beta-amyloid precursor protein in rat brain

1 reference

12 December 2020

Evidence that the 42- and 40-amino acid forms of amyloid beta protein are generated from the beta-amyloid precursor protein by different protease activities

1 reference

12 December 2020

Demonstration of functionally different interactions between phospholipase C-gamma and the two types of platelet-derived growth factor receptors

1 reference

12 December 2020

Secretion of the beta/A4 amyloid precursor protein. Identification of a cleavage site in cultured mammalian cells

1 reference

12 December 2020

Calcium regulates processing of the Alzheimer amyloid protein precursor in a protein kinase C-independent manner

1 reference

12 December 2020

Regulation of APP processing by intra- and intercellular signals

1 reference

12 December 2020

Regulated cleavage of Alzheimer beta-amyloid precursor protein in the absence of the cytoplasmic tail

1 reference

12 December 2020

Alzheimer's disease: genotypes, phenotypes, and treatments

1 reference

12 December 2020

Identification of two C-terminal autophosphorylation sites in the PDGF beta-receptor: involvement in the interaction with phospholipase C-gamma

1 reference

12 December 2020

Phospholipase C-gamma is a substrate for the PDGF and EGF receptor protein-tyrosine kinases in vivo and in vitro

1 reference

12 December 2020

Protein phosphorylation regulates secretion of Alzheimer beta/A4 amyloid precursor protein

1 reference

12 December 2020

Serotonin 5-HT2a and 5-HT2c receptors stimulate amyloid precursor protein ectodomain secretion

1 reference

12 December 2020

Nerve and epidermal growth factors induce the release of the Alzheimer amyloid precursor from PC 12 cell cultures.

1 reference

12 December 2020

10.1523/JNEUROSCI.17-24-09415.1997

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6573401&resulttype=core&format=json

15 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6573401&resulttype=core&format=json

15 May 2020

1 reference