(Q48574916)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22492027%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

title

Age-dependent rescue by simvastatin of Alzheimer's disease cerebrovascular and memory deficits (English)

1 reference

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28 January 2020

0 references

1 reference

2

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28 January 2020

author name string

Xin-Kang Tong

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22492027%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Edith Hamel

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22492027%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Pedro Rosa-Neto

series ordinal

3

1 reference

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28 January 2020

language of work or name

English

0 references

publication date

1 April 2012

1 reference

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28 January 2020

published in

Journal of Neuroscience

1 reference

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28 January 2020

volume

32

1 reference

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28 January 2020

issue

14

1 reference

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28 January 2020

page(s)

4705-4715

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22492027%20AND%20SRC:MED&resulttype=core&format=json

Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models

28 January 2020

cites work

1 reference

12 December 2020

SOD1 rescues cerebral endothelial dysfunction in mice overexpressing amyloid precursor protein

1 reference

12 December 2020

High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation

1 reference

12 December 2020

In vivo imaging of neuronal activation and plasticity in the rat brain by high resolution positron emission tomography (microPET)

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12 December 2020

The MAPK/ERK cascade targets both Elk-1 and cAMP response element-binding protein to control long-term potentiation-dependent gene expression in the dentate gyrus in vivo.

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12 December 2020

Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors.

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12 December 2020

Statins and the risk of dementia

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12 December 2020

A requirement for the immediate early gene Zif268 in the expression of late LTP and long-term memories.

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12 December 2020

Use of lipid-lowering agents, indication bias, and the risk of dementia in community-dwelling elderly people.

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12 December 2020

Alterations in cerebral blood flow and glucose utilization in mice overexpressing the amyloid precursor protein

1 reference

12 December 2020

Reversible inhibition of CREB/ATF transcription factors in region CA1 of the dorsal hippocampus disrupts hippocampus-dependent spatial memory.

1 reference

12 December 2020

Treatment with simvastatin in normocholesterolemic patients with Alzheimer's disease: A 26-week randomized, placebo-controlled, double-blind trial

1 reference

12 December 2020

Phosphatidylinositol 3-kinase: a molecule mediating BDNF-dependent spatial memory formation

1 reference

12 December 2020

MAPK, CREB and zif268 are all required for the consolidation of recognition memory

1 reference

12 December 2020

How necessary is the activation of the immediate early gene zif268 in synaptic plasticity and learning?

1 reference

12 December 2020

Selectively reduced expression of synaptic plasticity-related genes in amyloid precursor protein + presenilin-1 transgenic mice.

1 reference

12 December 2020

Neuronal depletion of calcium-dependent proteins in the dentate gyrus is tightly linked to Alzheimer's disease-related cognitive deficits

1 reference

12 December 2020

Impaired long-term memory and NR2A-type NMDA receptor-dependent synaptic plasticity in mice lacking c-Fos in the CNS.

1 reference

12 December 2020

Rosuvastatin treatment reverses impaired coronary artery vasodilation in fructose-fed, insulin-resistant rats

1 reference

12 December 2020

Neurovascular regulation in the normal brain and in Alzheimer's disease

1 reference

12 December 2020

Cerebrovascular dysfunction in Zucker obese rats is mediated by oxidative stress and protein kinase C.

1 reference

12 December 2020

Laser speckle flowmetry for the study of cerebrovascular physiology in normal and ischemic mouse cortex

1 reference

12 December 2020

Selective cholinergic denervation, independent from oxidative stress, in a mouse model of Alzheimer's disease

1 reference

12 December 2020

The prediction of rapid conversion to Alzheimer's disease in mild cognitive impairment using regional cerebral blood flow SPECT.

1 reference

12 December 2020

Vascular remodeling versus amyloid beta-induced oxidative stress in the cerebrovascular dysfunctions associated with Alzheimer's disease.

1 reference

12 December 2020

A specific amyloid-beta protein assembly in the brain impairs memory

1 reference

12 December 2020

Statin therapy in Alzheimer's disease

1 reference

12 December 2020

Peroxynitrite diminishes myogenic tone in cerebral arteries: role of nitrotyrosine and F-actin

1 reference

12 December 2020

Endothelial nitric oxide synthase activation leads to dilatory H2O2 production in mouse cerebral arteries

1 reference

12 December 2020

Altered navigational strategy use and visuospatial deficits in hAPP transgenic mice.

1 reference

12 December 2020

Simvastatin enhances learning and memory independent of amyloid load in mice.

1 reference

12 December 2020

Mapping the amphetamine-evoked changes in [11C]raclopride binding in living rat using small animal PET: modulation by MAO-inhibition.

1 reference

12 December 2020

Impairment of spatial memory consolidation in APP(751SL) mice results in cue-guided response.

1 reference

12 December 2020

Simvastatin and atorvastatin improve behavioral outcome, reduce hippocampal degeneration, and improve cerebral blood flow after experimental traumatic brain injury.

1 reference

12 December 2020

Effectiveness of treatment with donepezil hydrochloride and changes in regional cerebral blood flow in patients with Alzheimer's disease.

1 reference

12 December 2020

Statin therapy is associated with reduced neuropathologic changes of Alzheimer disease

1 reference

12 December 2020

Nox2-derived radicals contribute to neurovascular and behavioral dysfunction in mice overexpressing the amyloid precursor protein

1 reference

12 December 2020

Simvastatin-mediated upregulation of VEGF and BDNF, activation of the PI3K/Akt pathway, and increase of neurogenesis are associated with therapeutic improvement after traumatic brain injury

1 reference

12 December 2020

Effects of simvastatin on cerebrospinal fluid biomarkers and cognition in middle-aged adults at risk for Alzheimer's disease

1 reference

12 December 2020

Control of the establishment of aversive memory by calcineurin and Zif268.

1 reference

12 December 2020

Enkephalin elevations contribute to neuronal and behavioral impairments in a transgenic mouse model of Alzheimer's disease

1 reference

12 December 2020

Participation of K+ channels in the endothelium-dependent and endothelium-independent components of the relaxant effect of rosuvastatin in rat aortic rings

1 reference

12 December 2020

Use of statins and incidence of dementia and cognitive impairment without dementia in a cohort study

1 reference

12 December 2020

Simvastatin attenuation of cerebral vasospasm after subarachnoid hemorrhage in rats via increased phosphorylation of Akt and endothelial nitric oxide synthase

1 reference

12 December 2020

Complete rescue of cerebrovascular function in aged Alzheimer's disease transgenic mice by antioxidants and pioglitazone, a peroxisome proliferator-activated receptor gamma agonist

1 reference

12 December 2020

Statins are associated with a reduced risk of Alzheimer disease regardless of lipophilicity. The Rotterdam Study.

1 reference

12 December 2020

Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease

1 reference

12 December 2020

Cerebrovascular dysfunction in amyloid precursor protein transgenic mice: contribution of soluble and insoluble amyloid-beta peptide, partial restoration via gamma-secretase inhibition

1 reference

12 December 2020

Brain glucose hypometabolism and oxidative stress in preclinical Alzheimer's disease

1 reference

12 December 2020

Astrocytes and the regulation of cerebral blood flow

1 reference

12 December 2020

NMDA receptor-dependent signaling pathways that underlie amyloid beta-protein disruption of LTP in the hippocampus

1 reference

12 December 2020

{beta}-Amyloid impairs AMPA receptor trafficking and function by reducing Ca2+/calmodulin-dependent protein kinase II synaptic distribution

1 reference

12 December 2020

Simvastatin improves cerebrovascular function and counters soluble amyloid-beta, inflammation and oxidative stress in aged APP mice.

1 reference

12 December 2020

Antidiabetic effects of 11beta-HSD1 inhibition in a mouse model of combined diabetes, dyslipidaemia and atherosclerosis.

1 reference

12 December 2020

Simvastatin acutely reduces ischemic brain damage in the immature rat via Akt and CREB activation

1 reference

12 December 2020

Simvastatin enhances hippocampal long-term potentiation in C57BL/6 mice.

1 reference

12 December 2020

1 reference

12 December 2020

Membrane biophysics and mechanics in Alzheimer's disease.

1 reference

12 December 2020

Age-varying association between statin use and incident Alzheimer's disease

1 reference

12 December 2020

Intact memory in TGF-β1 transgenic mice featuring chronic cerebrovascular deficit: recovery with pioglitazone

1 reference

12 December 2020

Statins promote the degradation of extracellular amyloid {beta}-peptide by microglia via stimulation of exosome-associated insulin-degrading enzyme (IDE) secretion

1 reference

12 December 2020

Predominant enhancement of glucose uptake in astrocytes versus neurons during activation of the somatosensory cortex

1 reference

12 December 2020

Statin prevents chondrocyte aging and degeneration of articular cartilage in osteoarthritis (OA).

1 reference

12 December 2020

Atorvastatin and Aβ(1-40): not as simple as cholesterol reduction in brain and relevance to Alzheimer disease

1 reference

12 December 2020

Simvastatin is the statin that most efficiently protects against kainate-induced excitotoxicity and memory impairment.

1 reference

12 December 2020

Acute lipophilicity-dependent effect of intravascular simvastatin in the early phase of focal cerebral ischemia.

1 reference

12 December 2020

Scavenger receptor CD36 is essential for the cerebrovascular oxidative stress and neurovascular dysfunction induced by amyloid-beta

1 reference

12 December 2020

Induction of manganous superoxide dismutase by tumor necrosis factor: possible protective mechanism

1 reference

12 December 2020

Role of ATP-sensitive K+ channels in CGRP-induced dilatation of basilar artery in vivo

1 reference

12 December 2020

Pharmacological coupling and functional role for CGRP receptors in the vasodilation of rat pial arterioles

1 reference

12 December 2020

Decreased NGFI-A gene expression in the hippocampus of cognitively impaired aged rats.

1 reference

12 December 2020

10.1523/JNEUROSCI.0169-12.2012

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22492027%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22492027%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

PubMed publication ID

22492027

1 reference