(Q48585200)

13 February 2018

title

'Metabolic syndrome' in the brain: deficiency in omega-3 fatty acid exacerbates dysfunctions in insulin receptor signalling and cognition (English)

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13 February 2018

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1

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13 February 2018

Fernando Gomez-Pinilla

series ordinal

2

object named as

Fernando Gomez-Pinilla

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13 February 2018

language of work or name

English

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publication date

2 April 2012

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13 February 2018

published in

Journal of Physiology

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13 February 2018

volume

590

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13 February 2018

issue

10

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13 February 2018

page(s)

2485-2499

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13 February 2018

Omega-3 fatty acid deficiency during brain maturation reduces neuronal and behavioral plasticity in adulthood.

cites work

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5 October 2018

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A study of brain insulin receptors, AChE activity and oxidative stress in rat model of ICV STZ induced dementia

5 October 2018

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Fructose overconsumption causes dyslipidemia and ectopic lipid deposition in healthy subjects with and without a family history of type 2 diabetes

5 October 2018

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Brain foods: the effects of nutrients on brain function

5 October 2018

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Brain insulin, energy and glucose homeostasis; genes, environment and metabolic pathologies

5 October 2018

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Obesity and hypertriglyceridemia produce cognitive impairment

5 October 2018

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How relevant is the ratio of dietary n-6 to n-3 polyunsaturated fatty acids to cardiovascular disease risk? Evidence from the OPTILIP study

5 October 2018

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AMP-activated protein kinase phosphorylates transcription factors of the CREB family

5 October 2018

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Metabolic syndrome and mental illness

5 October 2018

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Effects of triglyceride on ER stress and insulin resistance

5 October 2018

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Fructose metabolism in the cerebellum

5 October 2018

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Oxidative stress modulates Sir2alpha in rat hippocampus and cerebral cortex.

5 October 2018

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Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases

5 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424766

Expression of fructose sensitive glucose transporter in the brains of fructose-fed rats

5 October 2018

1 reference

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Tyrosine phosphorylation of synaptophysin in synaptic vesicle recycling

5 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424766

A diet enriched with the omega-3 fatty acid docosahexaenoic acid reduces amyloid burden in an aged Alzheimer mouse model.

5 October 2018

1 reference

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Dietary omega-3 fatty acids normalize BDNF levels, reduce oxidative damage, and counteract learning disability after traumatic brain injury in rats

5 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424766

Biochemical regulation of mammalian AMP-activated protein kinase activity by NAD and NADH.

5 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424766

High dietary fructose induces a hepatic stress response resulting in cholesterol and lipid dysregulation

5 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424766

Neuroprotective Effect of Docosahexaenoic Acid-Enriched Phospholipids in Experimental Diabetic Neuropathy

5 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424766

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

5 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424766

Docosapentaenoic acid does not completely replace DHA in n-3 FA-deficient rats during early development

5 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424766

Sir2-dependent activation of acetyl-CoA synthetase by deacetylation of active lysine

5 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424766

Docosahexaenoic acid provides protection from impairment of learning ability in Alzheimer's disease model rats.

5 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424766

Ageing and diabetes: implications for brain function

5 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424766

Mechanisms of action of docosahexaenoic acid in the nervous system

5 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424766

The glial glutamate transporter, GLT-1, is oxidatively modified by 4-hydroxy-2-nonenal in the Alzheimer's disease brain: the role of Abeta1-42.

5 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424766

Effect of the long-term feeding of dietary lipids on the learning ability, fatty acid composition of brain stem phospholipids and synaptic membrane fluidity in adult mice: a comparison of sardine oil diet with palm oil diet

5 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424766

Fat distribution and changes in the blood brain barrier in a rat model of cerebral arterial fat embolism.

5 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424766

5 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424766

The lipid peroxidation product, 4-hydroxy-2-trans-nonenal, alters the conformation of cortical synaptosomal membrane proteins

5 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424766

A role for 4-hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion homeostasis and neuronal death induced by amyloid beta-peptide

5 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424766

Diabetes and fructose metabolism.

5 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424766

Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man

5 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424766

Molecular characterization of synaptophysin, a major calcium-binding protein of the synaptic vesicle membrane

5 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424766

Identification of synaptophysin as a hexameric channel protein of the synaptic vesicle membrane

5 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424766

Induction of formation of presynaptic terminals in neuroblastoma cells by synapsin IIb.

5 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424766

Antibodies to synaptophysin interfere with transmitter secretion at neuromuscular synapses

5 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424766

Exogenous synapsin I promotes functional maturation of developing neuromuscular synapses

5 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424766

Memory deficits associated with senescence: A neurophysiological and behavioral study in the rat

5 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424766

Dietary n-3 PUFA deprivation for 15 weeks upregulates elongase and desaturase expression in rat liver but not brain

5 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22473784

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Selective, physiological transport of insulin across the blood-brain barrier: novel demonstration by species-specific radioimmunoassays

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22473784

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1113/JPHYSIOL.2012.230078

1 reference

13 February 2018

PMC publication ID

3424766

0 references

1 reference

13 February 2018