(Q48591871)

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c-Jun N-terminal protein kinase (JNK) 2/3 is specifically activated by stress, mediating c-Jun activation, in the presence of constitutive JNK1 activity in cerebellar neurons.

scientific article published in June 2002

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Europe PubMed Central

PubMed publication ID

13 February 2018

http://europepmc.org/abstract/MED/12040039

c-Jun N-terminal protein kinase (JNK) 2/3 is specifically activated by stress, mediating c-Jun activation, in the presence of constitutive JNK1 activity in cerebellar neurons (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758801&resulttype=core&format=json

12 May 2020

Michael J Courtney

7

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758801&resulttype=core&format=json

12 May 2020

author name string

Eleanor T Coffey

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758801&resulttype=core&format=json

12 May 2020

Giedre Smiciene

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758801&resulttype=core&format=json

12 May 2020

Vesa Hongisto

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758801&resulttype=core&format=json

12 May 2020

Jiong Cao

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758801&resulttype=core&format=json

12 May 2020

Stephan Brecht

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758801&resulttype=core&format=json

12 May 2020

Thomas Herdegen

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758801&resulttype=core&format=json

12 May 2020

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publication date

1 June 2002

1 reference

Europe PubMed Central

PubMed publication ID

13 February 2018

http://europepmc.org/abstract/MED/12040039

Journal of Neuroscience

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758801&resulttype=core&format=json

12 May 2020

22

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758801&resulttype=core&format=json

12 May 2020

11

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758801&resulttype=core&format=json

12 May 2020

4335-4345

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758801&resulttype=core&format=json

12 May 2020

Cascade of caspase activation in potassium-deprived cerebellar granule neurons: targets for treatment with peptide and protein inhibitors of apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dual roles for c-Jun N-terminal kinase in developmental and stress responses in cerebellar granule neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that of other SAP kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The c-Jun transcription factor--bipotential mediator of neuronal death, survival and regeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Observations on rat cerebellar cells in vitro: influence of substratum, potassium concentration and relationship between neurones and astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The JIP group of mitogen-activated protein kinase scaffold proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A mammalian scaffold complex that selectively mediates MAP kinase activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective interaction of JNK protein kinase isoforms with transcription factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis of cerebellar granule cells induced by serum withdrawal, glutamate or beta-amyloid, is independent of Jun kinase or p38 mitogen activated protein kinase activation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of p38 mitogen-activated protein kinase in axotomy-induced apoptosis of rat retinal ganglion cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A nuclear tyrosine phosphorylation circuit: c-Jun as an activator and substrate of c-Abl and JNK.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pyridinylimidazole compound SB 203580 inhibits the activity but not the activation of p38 mitogen-activated protein kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A cytoplasmic inhibitor of the JNK signal transduction pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel homologues of CSBP/p38 MAP kinase: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mechanism of Ara-C-induced apoptosis of differentiating cerebellar granule neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p38-2, a novel mitogen-activated protein kinase with distinct properties.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The primary structure of p38 gamma: a new member of p38 group of MAP kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal activity-dependent cell survival mediated by transcription factor MEF2

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of the Abl protein-tyrosine kinase in vitro and in vivo by a 2-phenylaminopyrimidine derivative.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor induction of the c-jun promoter by a Rac pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The stress-activated protein kinase subfamily of c-Jun kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

c-Jun mediates axotomy-induced dopamine neuron death in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specificity and mechanism of action of some commonly used protein kinase inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of the MEF2 family of transcription factors by p38

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical and functional analysis of highly phosphorylated forms of c-Jun protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotrophins protect cultured cerebellar granule neurons against the early phase of cell death by a two-component mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation and involvement of p38 mitogen-activated protein kinase in glutamate-induced apoptosis in rat cerebellar granule cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiapoptotic role of the p38 mitogen-activated protein kinase-myocyte enhancer factor 2 transcription factor pathway during neuronal differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p38 mitogen-activated protein kinase regulates low potassium-induced c-Jun phosphorylation and apoptosis in cultured cerebellar granule neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of mitogen-activated protein kinase pathways used by interleukin 1 in tissues in vivo: activation of hepatic c-Jun N-terminal kinases 1 and 2, and mitogen-activated protein kinase kinases 4 and 7.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of c-Jun is necessary for apoptosis induced by survival signal withdrawal in cerebellar granule neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of p38 and JNK mitogen-activated protein kinases in the activation of ternary complex factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intramolecular signal transduction in c-Jun

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of c-jun mediated by MAP kinases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/12040039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.22-11-04335.2002

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758801&resulttype=core&format=json

12 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758801&resulttype=core&format=json

12 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758801&resulttype=core&format=json

12 May 2020

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