(Q48630808)

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The neuronal serum- and glucocorticoid-regulated kinase 1.1 reduces neuronal excitability and protects against seizures through upregulation of the M-current.

scientific article published in February 2013

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scholarly article

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Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/23392695

The neuronal serum- and glucocorticoid-regulated kinase 1.1 reduces neuronal excitability and protects against seizures through upregulation of the M-current. (English)

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/23392695

Diego Alvarez de la Rosa

7

1 reference

Europe PubMed Central

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15 May 2020

Teresa Giráldez Fernández

8

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15 May 2020

1

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15 May 2020

Tomas Gonzalez-Hernandez

5

1 reference

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15 May 2020

J Antonio Lamas

6

1 reference

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15 May 2020

Rafaela González-Montelongo

3

object named as

Rafaela González-Montelongo

1 reference

Europe PubMed Central

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15 May 2020

author name string

Alba Cadaveira-Mosquera

2

1 reference

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15 May 2020

Alvaro Villarroel

4

1 reference

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15 May 2020

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publication date

1 February 2013

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/23392695

Journal of Neuroscience

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15 May 2020

33

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15 May 2020

2684-2696

1 reference

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15 May 2020

6

1 reference

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15 May 2020

Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The serum and glucocorticoid kinase sgk increases the abundance of epithelial sodium channels in the plasma membrane of Xenopus oocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reconstitution of muscarinic modulation of the KCNQ2/KCNQ3 K(+) channels that underlie the neuronal M current

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Surface expression and single channel properties of KCNQ2/KCNQ3, M-type K+ channels involved in epilepsy

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

M-type KCNQ2-KCNQ3 potassium channels are modulated by the KCNE2 subunit

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel mouse Nedd4 protein suppresses the activity of the epithelial Na+ channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new method for generating point mutations in bacterial artificial chromosomes by homologous recombination in Escherichia coli

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal KCNQ potassium channels: physiology and role in disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum and glucocorticoid-regulated kinase modulates Nedd4-2-mediated inhibition of the epithelial Na+ channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of Nedd4-2 by Sgk1 regulates epithelial Na(+) channel cell surface expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation between electrical activity and intracellular Ca2+ oscillations in GH3 rat anterior pituitary cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ionic basis of the resting membrane potential in cultured rat sympathetic neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recovery from muscarinic modulation of M current channels requires phosphatidylinositol 4,5-bisphosphate synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subunit-specific modulation of KCNQ potassium channels by Src tyrosine kinase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A carboxy-terminal domain determines the subunit specificity of KCNQ K+ channel assembly

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PIP(2) activates KCNQ channels, and its hydrolysis underlies receptor-mediated inhibition of M currents

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stoichiometry of expressed KCNQ2/KCNQ3 potassium channels and subunit composition of native ganglionic M channels deduced from block by tetraethylammonium

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

International Union of Pharmacology. XLI. Compendium of voltage-gated ion channels: potassium channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of the voltage gated K+ channel Kv1.3 by the ubiquitin ligase Nedd4-2 and the serum and glucocorticoid inducible kinase SGK1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Newly developed blockers of the M-current do not reduce spike frequency adaptation in cultured mouse sympathetic neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correction for liquid junction potentials in patch clamp experiments

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dual phosphorylations underlie modulation of unitary KCNQ K(+) channels by Src tyrosine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum and glucocorticoid inducible kinases functionally regulate ClC-2 channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Three mechanisms underlie KCNQ2/3 heteromeric potassium M-channel potentiation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Laboratory animal models of temporal lobe epilepsy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship between membrane phosphatidylinositol-4,5-bisphosphate and receptor-mediated inhibition of native neuronal M channels.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural requirements for differential sensitivity of KCNQ K+ channels to modulation by Ca2+/calmodulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C shifts the voltage dependence of KCNQ/M channels expressed in Xenopus oocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of Kv7 (KCNQ) K+ channel open probability by phosphatidylinositol 4,5-bisphosphate.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathways modulating neural KCNQ/M (Kv7) potassium channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

KCNQ channels mediate IKs, a slow K+ current regulating excitability in the rat node of Ranvier

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural determinants of M-type KCNQ (Kv7) K+ channel assembly.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiotensin II regulates neuronal excitability via phosphatidylinositol 4,5-bisphosphate-dependent modulation of Kv7 (M-type) K+ channels.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lysosomal storage disease upon disruption of the neuronal chloride transport protein ClC-6.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of the voltage-gated K(+) channels KCNQ2/3 and KCNQ3/5 by ubiquitination. Novel role for Nedd4-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple translational isoforms give functional specificity to serum- and glucocorticoid-induced kinase 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Where does all the PIP2 come from?

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of neural KCNQ channels: signalling pathways, structural motifs and functional implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A brain-specific SGK1 splice isoform regulates expression of ASIC1 in neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of the voltage-gated K(+) channels KCNQ2/3 and KCNQ3/5 by serum- and glucocorticoid-regulated kinase-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of age on kainate-induced seizure severity and cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analyzing real-time PCR data by the comparative C(T) method

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An evolutionarily conserved N-terminal Sgk1 variant with enhanced stability and improved function.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determinants within the turret and pore-loop domains of KCNQ3 K+ channels governing functional activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contribution of KCNQ2 and KCNQ3 to the medium and slow afterhyperpolarization currents

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A riluzole- and valproate-sensitive persistent sodium current contributes to the resting membrane potential and increases the excitability of sympathetic neurones

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The lupane-type triterpene 30-oxo-calenduladiol is a CCR5 antagonist with anti-HIV-1 and anti-chemotactic activities

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetics of PIP2 metabolism and KCNQ2/3 channel regulation studied with a voltage-sensitive phosphatase in living cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Depolarization increases phosphatidylinositol (PI) 4,5-bisphosphate level and KCNQ currents through PI 4-kinase mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphoinositides: lipid regulators of membrane proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A pore residue of the KCNQ3 potassium M-channel subunit controls surface expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neuronal-specific SGK1.1 kinase regulates {delta}-epithelial Na+ channel independently of PY motifs and couples it to phospholipase C signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low access resistance perforated patch recordings using amphotericin B.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of TREK currents by the neuroprotective agent riluzole in mouse sympathetic neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane depolarization increases membrane PtdIns(4,5)P2 levels through mechanisms involving PKC βII and PI4 kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kv7 channels can function without constitutive calmodulin tethering

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential N termini in epithelial Na+ channel δ-subunit isoforms modulate channel trafficking to the membrane.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coordinated signal integration at the M-type potassium channel upon muscarinic stimulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Muscarinic suppression of the M-current in the rat sympathetic ganglion is mediated by receptors of the M1-subtype

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modification of seizure activity by electrical stimulation. II. Motor seizure

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Muscarinic suppression of a novel voltage-sensitive K+ current in a vertebrate neurone

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kainic acid induced limbic seizures: metabolic, behavioral, electroencephalographic and neuropathological correlates

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

WW domains of Nedd4 bind to the proline-rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of M-current

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel potassium channel gene, KCNQ2, is mutated in an inherited epilepsy of newborns

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A pore mutation in a novel KQT-like potassium channel gene in an idiopathic epilepsy family

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A potassium channel mutation in neonatal human epilepsy

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modalities of distortion of physiological voltage signals by patch-clamp amplifiers: a modeling study

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A hyperpolarization-activated cation current (Ih) contributes to resting membrane potential in rat superior cervical sympathetic neurones.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidylinositol 4-kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of human erg K+ channel gating by activation of a G protein-coupled receptor and protein kinase C.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

KCNQ2 and KCNQ3 potassium channel subunits: molecular correlates of the M-channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Moderate loss of function of cyclic-AMP-modulated KCNQ2/KCNQ3 K+ channels causes epilepsy

1 reference

https://pubmed.ncbi.nlm.nih.gov/23392695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.3442-12.2013

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6619182&resulttype=core&format=json

15 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6619182&resulttype=core&format=json

15 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6619182&resulttype=core&format=json

15 May 2020

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