(Q48673228)

14 February 2018

title

Turn motif phosphorylation negatively regulates activation loop phosphorylation in Akt. (English)

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14 February 2018

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D Hiraoka

1

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14 February 2018

E Okumura

series ordinal

2

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14 February 2018

T Kishimoto

series ordinal

3

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14 February 2018

language of work or name

English

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publication date

16 May 2011

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14 February 2018

published in

Oncogene

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14 February 2018

volume

30

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14 February 2018

issue

44

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14 February 2018

page(s)

4487-4497

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14 February 2018

https://scigraph.springernature.com/pub.10.1038/onc.2011.155

exact match

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cites work

3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase

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Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

21 January 2018

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Activation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.155

Akt forms an intracellular complex with heat shock protein 90 (Hsp90) and Cdc37 and is destabilized by inhibitors of Hsp90 function

21 January 2018

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21 January 2018

The two TORCs and Akt.

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Threonine 308 phosphorylated form of Akt translocates to the nucleus of PC12 cells under nerve growth factor stimulation and associates with the nuclear matrix protein nucleolin.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.155

Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin

21 January 2018

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Induction of starfish oocyte maturation by the beta gamma subunit of starfish G protein and possible existence of the subsequent effector in cytoplasm

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.155

TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver

21 January 2018

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Regulation of the Akt kinase by interacting proteins

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The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C

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Protein kinase B/Akt at a glance

21 January 2018

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Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2

21 January 2018

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Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR)

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.155

Thr308 determines Akt1 nuclear localization in insulin-stimulated keratinocytes

21 January 2018

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Hormonal control of reinitiation of meiosis in starfish. The requirement of 1-methyladenine during nuclear maturation

21 January 2018

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Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1

21 January 2018

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Start of the embryonic cell cycle is dually locked in unfertilized starfish eggs.

21 January 2018

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Mechanism for activation of the growth factor-activated AGC kinases by turn motif phosphorylation

21 January 2018

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Scaffolding function of PAK in the PDK1-Akt pathway

21 January 2018

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Insulin-stimulated protein kinase B phosphorylation on Ser-473 is independent of its activity and occurs through a staurosporine-insensitive kinase

21 January 2018

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PDK1 is required for the hormonal signaling pathway leading to meiotic resumption in starfish oocytes.

21 January 2018

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Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling

21 January 2018

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SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.155

Oocyte maturation in starfish is mediated by the beta gamma-subunit complex of a G-protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.155

Interaction between Src and a C-terminal proline-rich motif of Akt is required for Akt activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.155

PKB/AKT is involved in resumption of meiosis in mouse oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.155

Cell-cycle control during meiotic maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.155

Akt, a pleckstrin homology domain containing kinase, is activated primarily by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.155

Regulation of phosphorylation of Thr-308 of Akt, cell proliferation, and survival by the B55alpha regulatory subunit targeting of the protein phosphatase 2A holoenzyme to Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.155

PHAS-I as a link between mitogen-activated protein kinase and translation initiation

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.155

Molecular mechanisms of mTOR-mediated translational control

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.155

AKT/PKB signaling: navigating downstream

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.155

Akt inhibits Myt1 in the signalling pathway that leads to meiotic G2/M-phase transition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.155

Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.155

From man to mouse and back again: advances in defining tumor AKTivities in vivo.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.155

Components of the signaling pathway linking the 1-methyladenine receptor to MPF activation and maturation in starfish oocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.155

Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.155

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.155

Modulation of Akt kinase activity by binding to Hsp90

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.155

Multiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.155

Akt/protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.155

Activation of Akt (protein kinase B) stimulates metaphase I to metaphase II transition in bovine oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.155

Protein phosphatase 2A negatively regulates insulin's metabolic signaling pathway by inhibiting Akt (protein kinase B) activity in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.155

Isolation and Identification of Meiosis Inducing Substance in Starfish Asterias amurensis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.155

Mechanism of activation of protein kinase B by insulin and IGF-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.155

31 March 2020

Identifiers

DOI

10.1038/ONC.2011.155

1 reference

14 February 2018

Dimensions Publication ID

1004754589

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1 reference

14 February 2018