(Q48681676)

14 February 2018

title

Development of a (18) F-labeled tetrazine with favorable pharmacokinetics for bioorthogonal PET imaging (English)

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14 February 2018

main subject

bioorthogonal chemistry

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1 reference

7

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14 February 2018

Hannes Mikula

8

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14 February 2018

Dennis Svatunek

Dennis Svatunek

2

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Johannes Fröhlich

6

Johannes Fröhlich

1 reference

14 February 2018

Christoph Denk

1

Christoph Denk

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14 February 2018

Thomas Wanek

4

Thomas Wanek

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14 February 2018

Daniel Lumpi

5

Daniel Lumpi

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14 February 2018

author name string

Thomas Filip

3

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14 February 2018

language of work or name

English

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publication date

2 July 2014

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14 February 2018

Angewandte Chemie International Edition

published in

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volume

53

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14 February 2018

issue

36

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14 February 2018

page(s)

9655-9659

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14 February 2018

Bioorthogonal chemistry for pre-targeted molecular imaging--progress and prospects

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From mechanism to mouse: a tale of two bioorthogonal reactions

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Copper-free click chemistry for dynamic in vivo imaging

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In vivo imaging of membrane-associated glycans in developing zebrafish

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Selective fluorescence labeling of lipids in living cells

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Genetically encoded copper-free click chemistry

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Cell-selective metabolic labeling of biomolecules with bioorthogonal functionalities.

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Cu-free click cycloaddition reactions in chemical biology

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Rapid Cu-free click chemistry with readily synthesized biarylazacyclooctynones

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Thiacycloalkynes for copper-free click chemistry

21 January 2018

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Mesoporous silica nanoparticle pretargeting for PET imaging based on a rapid bioorthogonal reaction in a living body

21 January 2018

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Tetrazine ligation: fast bioconjugation based on inverse-electron-demand Diels-Alder reactivity

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Tetrazine-based cycloadditions: application to pretargeted live cell imaging

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Bioorthogonal probes for polo-like kinase 1 imaging and quantification.

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Genetically encoded norbornene directs site-specific cellular protein labelling via a rapid bioorthogonal reaction

21 January 2018

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Bioorthogonal imaging of aurora kinase A in live cells

21 January 2018

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Diels-Alder cycloaddition for fluorophore targeting to specific proteins inside living cells

21 January 2018

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Genetically encoded tetrazine amino acid directs rapid site-specific in vivo bioorthogonal ligation with trans-cyclooctenes

21 January 2018

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Bioorthogonal small molecule imaging agents allow single-cell imaging of MET

21 January 2018

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Synthesis and in vivo imaging of a 18F-labeled PARP1 inhibitor using a chemically orthogonal scavenger-assisted high-performance method.

21 January 2018

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Bioorthogonal reaction pairs enable simultaneous, selective, multi-target imaging

21 January 2018

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BODIPY-tetrazine derivatives as superbright bioorthogonal turn-on probes

21 January 2018

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Design and synthesis of highly reactive dienophiles for the tetrazine-trans-cyclooctene ligation.

21 January 2018

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trans-Cyclooctene--a stable, voracious dienophile for bioorthogonal labeling

21 January 2018

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Live-cell imaging of cyclopropene tags with fluorogenic tetrazine cycloadditions

21 January 2018

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Expanding room for tetrazine ligations in the in vivo chemistry toolbox

21 January 2018

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Tetrazine-trans-cyclooctene ligation for the rapid construction of 18F labeled probes.

21 January 2018

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Synthesis and evaluation of an 18F-labelled norbornene derivative for copper-free click chemistry reactions.

21 January 2018

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Development of a (11)C-labeled tetrazine for rapid tetrazine-trans-cyclooctene ligation

21 January 2018

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In vivo chemistry for pretargeted tumor imaging in live mice.

21 January 2018

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A pretargeted PET imaging strategy based on bioorthogonal Diels-Alder click chemistry.

21 January 2018

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Reactive polymer enables efficient in vivo bioorthogonal chemistry.

21 January 2018

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Synthesis and evaluation of a series of 1,2,4,5-tetrazines for bioorthogonal conjugation

21 January 2018

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Diels-Alder reactivities of strained and unstrained cycloalkenes with normal and inverse-electron-demand dienes: activation barriers and distortion/interaction analysis

21 January 2018

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Efficient (18)F-Labeling of Synthetic Exendin-4 Analogues for Imaging Beta Cells

21 January 2018

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High-yielding, two-step 18F labeling strategy for 18F-PARP1 inhibitors

21 January 2018

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Modular strategy for the construction of radiometalated antibodies for positron emission tomography based on inverse electron demand Diels-Alder click chemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201404277

Development of a bioorthogonal and highly efficient conjugation method for quantum dots using tetrazine-norbornene cycloaddition

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201404277

Bioorthogonal chemistry amplifies nanoparticle binding and enhances the sensitivity of cell detection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201404277

Metal-catalyzed one-pot synthesis of tetrazines directly from aliphatic nitriles and hydrazine

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201404277

Highly reactive trans-cyclooctene tags with improved stability for Diels-Alder chemistry in living systems.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201404277

18F-Fluoride positron emission tomography and positron emission tomography/computed tomography

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201404277

21 January 2018

Identifiers

DOI

10.1002/ANIE.201404277

1 reference

14 February 2018

1 reference

14 February 2018