(Q48696484)

14 February 2018

title

Toxicity of novel C-terminal prion protein fragments and peptides harbouring disease-related C-terminal mutations (English)

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14 February 2018

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M Daniels

1

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14 February 2018

G M Cereghetti

series ordinal

2

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14 February 2018

D R Brown

series ordinal

3

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14 February 2018

language of work or name

English

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publication date

1 December 2001

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14 February 2018

published in

FEBS Journal

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14 February 2018

volume

268

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14 February 2018

issue

23

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14 February 2018

page(s)

6155-6164

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14 February 2018

Developmental expression of the prion protein gene in glial cells.

cites work

1 reference

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Prion protein peptide neurotoxicity can be mediated by astrocytes

21 January 2018

1 reference

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Microglial expression of the prion protein

21 January 2018

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Activation effects of a prion protein fragment [PrP-(106-126)] on human leucocytes

21 January 2018

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Differential release of cellular and scrapie prion proteins from cellular membranes by phosphatidylinositol-specific phospholipase C.

21 January 2018

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Cellular prion protein localization in rodent and primate brain

21 January 2018

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Prion protein is necessary for normal synaptic function

21 January 2018

1 reference

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The cellular prion protein binds copper in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02567.X

Antioxidant activity related to copper binding of native prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02567.X

Prion protein expression and superoxide dismutase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02567.X

Normal prion protein has an activity like that of superoxide dismutase.

21 January 2018

1 reference

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Truncated forms of the human prion protein in normal brain and in prion diseases.

21 January 2018

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Purification and properties of the cellular prion protein from Syrian hamster brain

21 January 2018

1 reference

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Phorbol ester-regulated cleavage of normal prion protein in HEK293 human cells and murine neurons

21 January 2018

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21 January 2018

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Novel proteinaceous infectious particles cause scrapie

21 January 2018

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Normal host prion protein necessary for scrapie-induced neurotoxicity.

21 January 2018

1 reference

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Mice devoid of PrP are resistant to scrapie

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02567.X

Neurotoxicity of a prion protein fragment

21 January 2018

1 reference

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Role of microglia and host prion protein in neurotoxicity of a prion protein fragment.

21 January 2018

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Synthetic peptides homologous to prion protein residues 106-147 form amyloid-like fibrils in vitro

21 January 2018

1 reference

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A nonfibrillar form of the fusogenic prion protein fragment [118-135] induces apoptotic cell death in rat cortical neurons.

21 January 2018

1 reference

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Sublethal concentrations of prion peptide PrP106-126 or the amyloid beta peptide of Alzheimer's disease activates expression of proapoptotic markers in primary cortical neurons.

21 January 2018

1 reference

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Prion protein-deficient cells show altered response to oxidative stress due to decreased SOD-1 activity

21 January 2018

1 reference

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PrPSc-like prion protein peptide inhibits the function of cellular prion protein

21 January 2018

1 reference

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Prion protein of 106 residues creates an artifical transmission barrier for prion replication in transgenic mice

21 January 2018

1 reference

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Heritable disorder resembling neuronal storage disease in mice expressing prion protein with deletion of an alpha-helix

21 January 2018

1 reference

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Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions

21 January 2018

1 reference

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Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02567.X

129/Ola mice carrying a null mutation in PrP that abolishes mRNA production are developmentally normal

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02567.X

Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02567.X

Influence of amino acid substitutions related to inherited human prion diseases on the thermodynamic stability of the cellular prion protein.

21 January 2018

1 reference

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Processing of a cellular prion protein: identification of N- and C-terminal cleavage sites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02567.X

Analysis of 27 mammalian and 9 avian PrPs reveals high conservation of flexible regions of the prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02567.X

Prion protein NMR structure and familial human spongiform encephalopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02567.X

NMR structure of the mouse prion protein domain PrP(121-231)

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02567.X

Autonomous and reversible folding of a soluble amino-terminally truncated segment of the mouse prion protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02567.X

NMR solution structure of the human prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02567.X

Recombinant full-length murine prion protein, mPrP(23-231): purification and spectroscopic characterization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02567.X

Prion protein expression in muscle cells and toxicity of a prion protein fragment

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02567.X

cDNA cloning of turtle prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02567.X

B lymphocytes and neuroinvasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02567.X

Prion protein expression aids cellular uptake and veratridine-induced release of copper

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02567.X

Effect of flupirtine on Bcl-2 and glutathione level in neuronal cells treated in vitro with the prion protein fragment (PrP106-126)

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02567.X

Neurotoxicity of the Putative Transmembrane Domain of the Prion Protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02567.X

The stimulation of inducible nitric-oxide synthase by the prion protein fragment 106--126 in human microglia is tumor necrosis factor-alpha-dependent and involves p38 mitogen-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02567.X

Mouse cortical cells lacking cellular PrP survive in culture with a neurotoxic PrP fragment

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02567.X

PrP and beta-amyloid fragments activate different neurotoxic mechanisms in cultured mouse cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02567.X

Prion protein peptides: optimal toxicity and peptide blockade of toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02567.X

In vivo cytotoxicity of the prion protein fragment 106-126

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02567.X

10.1046/J.0014-2956.2001.02567.X

21 January 2018

Identifiers

DOI

1 reference

14 February 2018

1 reference

14 February 2018