(Q48756991)

15 February 2018

title

Tau's role in the developing brain: implications for intellectual disability. (English)

1 reference

15 February 2018

author

Orly Reiner

5

1 reference

15 February 2018

Eva-Maria Mandelkow

4

object named as

Eva-Maria Mandelkow

1 reference

15 February 2018

Tamar Sapir

1

1 reference

15 February 2018

Michael Frotscher

2

1 reference

15 February 2018

Talia Levy

3

1 reference

15 February 2018

publication date

21 December 2011

1 reference

15 February 2018

published in

Human Molecular Genetics

1 reference

15 February 2018

volume

21

1 reference

15 February 2018

issue

8

1 reference

15 February 2018

page(s)

1681-1692

1 reference

15 February 2018

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

1 reference

Role of tau protein in both physiological and pathological conditions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Tau in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

The role of tau (MAPT) in frontotemporal dementia and related tauopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Missense and silent tau gene mutations cause frontotemporal dementia with parkinsonism-chromosome 17 type, by affecting multiple alternative RNA splicing regulatory elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Microdeletion encompassing MAPT at chromosome 17q21.3 is associated with developmental delay and learning disability

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Discovery of previously unidentified genomic disorders from the duplication architecture of the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

A new chromosome 17q21.31 microdeletion syndrome associated with a common inversion polymorphism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

A 17q21.31 microdeletion encompassing the MAPT gene in a mentally impaired patient.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Clinical and molecular delineation of the 17q21.31 microdeletion syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Solving the autism puzzle a few pieces at a time

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Multiple Recurrent De Novo CNVs, Including Duplications of the 7q11.23 Williams Syndrome Region, Are Strongly Associated with Autism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Rare De Novo and Transmitted Copy-Number Variation in Autistic Spectrum Disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Rare de novo variants associated with autism implicate a large functional network of genes involved in formation and function of synapses

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Recurrent reciprocal 1q21.1 deletions and duplications associated with microcephaly or macrocephaly and developmental and behavioral abnormalities

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Strong association of de novo copy number mutations with sporadic schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Rare chromosomal deletions and duplications increase risk of schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Large recurrent microdeletions associated with schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

X-chromosome tiling path array detection of copy number variants in patients with chromosome X-linked mental retardation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Recurrent rearrangements in synaptic and neurodevelopmental genes and shared biologic pathways in schizophrenia, autism, and mental retardation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Pattern of tau isoforms expression during development in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Isoforms changes of tau protein during development in various species

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Polarity regulation in migrating neurons in the cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Trekking across the brain: the journey of neuronal migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Altered microtubule organization in small-calibre axons of mice lacking tau protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Muscle weakness, hyperactivity, and impairment in fear conditioning in tau-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Defects in axonal elongation and neuronal migration in mice with disrupted tau and map1b genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

RNAi reveals doublecortin is required for radial migration in rat neocortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Doublecortin-like kinase functions with doublecortin to mediate fiber tract decussation and neuronal migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Accurate balance of the polarity kinase MARK2/Par-1 is required for proper cortical neuronal migration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

MARK/PAR1 kinase is a regulator of microtubule-dependent transport in axons

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Assembling the presynaptic active zone: a characterization of an active one precursor vesicle

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Cellular and molecular mechanisms of presynaptic assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Isolation of a Miller-Dieker lissencephaly gene containing G protein beta-subunit-like repeats

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Reduction of microtubule catastrophe events by LIS1, platelet-activating factor acetylhydrolase subunit.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

LIS1, CLIP-170's key to the dynein/dynactin pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

A novel CNS gene required for neuronal migration and involved in X-linked subcortical laminar heterotopia and lissencephaly syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Doublecortin, a brain-specific gene mutated in human X-linked lissencephaly and double cortex syndrome, encodes a putative signaling protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Doublecortin is a developmentally regulated, microtubule-associated protein expressed in migrating and differentiating neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Doublecortin is a microtubule-associated protein and is expressed widely by migrating neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Doublecortin, a stabilizer of microtubules

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Doublecortin mutations cluster in evolutionarily conserved functional domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Mutations in alpha-tubulin cause abnormal neuronal migration in mice and lissencephaly in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Large spectrum of lissencephaly and pachygyria phenotypes resulting from de novo missense mutations in tubulin alpha 1A (TUBA1A).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

TUBA1A mutations cause wide spectrum lissencephaly (smooth brain) and suggest that multiple neuronal migration pathways converge on alpha tubulins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Disease-associated mutations in TUBA1A result in a spectrum of defects in the tubulin folding and heterodimer assembly pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Disrupted-In-Schizophrenia 1 regulates integration of newly generated neurons in the adult brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Disc1 regulates granule cell migration in the developing hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Disruption of two novel genes by a translocation co-segregating with schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Increased LIS1 expression affects human and mouse brain development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

14-3-3epsilon is important for neuronal migration by binding to NUDEL: a molecular explanation for Miller-Dieker syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Further molecular and clinical delineation of co-locating 17p13.3 microdeletions and microduplications that show distinctive phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Genomic copy number variations at 17p13.3 and epileptogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Deletion of YWHAE in a patient with periventricular heterotopias and pronounced corpus callosum hypoplasia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Microdeletions including YWHAE in the Miller-Dieker syndrome region on chromosome 17p13.3 result in facial dysmorphisms, growth restriction, and cognitive impairment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

A protein factor essential for microtubule assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Purification of tau, a microtubule-associated protein that induces assembly of microtubules from purified tubulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Tau protein function in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Doublecortin associates with microtubules preferentially in regions of the axon displaying actin-rich protrusive structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Tau protects microtubules in the axon from severing by katanin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Tau consists of a set of proteins with repeated C-terminal microtubule-binding domains and variable N-terminal domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Differential regulation of dynein and kinesin motor proteins by tau

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Interaction of tau protein with the dynactin complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Dynactin enhances the processivity of kinesin-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Regulators of the cytoplasmic dynein motor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Dynactin: coordinating motors with opposite inclinations

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Convergent evidence identifying MAP/microtubule affinity-regulating kinase 1 (MARK1) as a susceptibility gene for autism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Identification of Tau and MAP2 as novel substrates of Rho-kinase and myosin phosphatase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

PAK5 kinase is an inhibitor of MARK/Par-1, which leads to stable microtubules and dynamic actin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Tau impacts on growth-factor-stimulated actin remodeling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Signaling from MARK to tau: regulation, cytoskeletal crosstalk, and pathological phosphorylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Reelin stabilizes the actin cytoskeleton of neuronal processes by inducing n-cofilin phosphorylation at serine3

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Reelin and brain development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Reelin glycoprotein: structure, biology and roles in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Role of MAP1B in axonal retrograde transport of mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

The tau mutation (val337met) disrupts cytoskeletal networks of microtubules

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: implications for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Mitochondria: the next (neurode)generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Altered calcium homeostasis in autism-spectrum disorders: evidence from biochemical and genetic studies of the mitochondrial aspartate/glutamate carrier AGC1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Mitochondrial dysfunction in autism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Global developmental gene expression and pathway analysis of normal brain development and mouse models of human neuronal migration defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Neuronal migration and neurodegeneration: 2 sides of the same coin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

The distribution of tau in the mammalian central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Selective stabilization of tau in axons and microtubule-associated protein 2C in cell bodies and dendrites contributes to polarized localization of cytoskeletal proteins in mature neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Transcription factor MEF2C influences neural stem/progenitor cell differentiation and maturation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Dendritic and synaptic pathology in mental retardation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Dendritic pathology in mental retardation: from molecular genetics to neurobiology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Corticotropin-releasing factor receptors differentially regulate stress-induced tau phosphorylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Intramembrane-cleaving proteases: controlled liberation of proteins and bioactive peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Evidence suggesting that Homo neanderthalensis contributed the H2 MAPT haplotype to Homo sapiens

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Evolutionary toggling of the MAPT 17q21.31 inversion region

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

The MAPT H1c risk haplotype is associated with increased expression of tau and especially of 4 repeat containing transcripts

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Tau reduction prevents Abeta-induced defects in axonal transport.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

21 January 2018

The many faces of tau

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

Membrane-bound β-amyloid oligomers are recruited into lipid rafts by a fyn-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR603

21 January 2018

Identifiers

DOI

10.1093/HMG/DDR603

1 reference

15 February 2018

release_uwb5cl32irg7fgoshcz77b3dh4

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/uwb5cl32irg7fgoshcz77b3dh4

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

15 February 2018