(Q48775208)

English

Combination of cationic dexamethasone derivative and STAT3 inhibitor (WP1066) for aggressive melanoma: a strategy for repurposing a phase I clinical trial drug.

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28585089%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Combination of cationic dexamethasone derivative and STAT3 inhibitor (WP1066) for aggressive melanoma: a strategy for repurposing a phase I clinical trial drug (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28585089%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

phase I clinical trial

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1 reference

based on heuristic

inferred from title

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28585089%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Sujan Kumar Mondal

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28585089%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Rajkumar Banerjee

5

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28585089%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

author name string

Sushil K Kashaw

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28585089%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Arun K Iyer

4

1 reference

Europe PubMed Central

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22 March 2020

publication date

5 June 2017

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28585089%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Molecular and Cellular Biochemistry

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28585089%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

436

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28585089%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

1-2

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28585089%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

119-136

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28585089%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

https://scigraph.springernature.com/pub.10.1007/s11010-017-3084-z

0 references

Mechanisms of cancer drug resistance

1 reference

https://api.crossref.org/works/10.1007%2FS11010-017-3084-Z

21 January 2018

Cancer genome landscapes

1 reference

https://api.crossref.org/works/10.1007%2FS11010-017-3084-Z

21 January 2018

Drug resistance in cancer: an overview.

1 reference

https://api.crossref.org/works/10.1007%2FS11010-017-3084-Z

21 January 2018

Iniparib plus chemotherapy in metastatic triple-negative breast cancer

1 reference

https://api.crossref.org/works/10.1007%2FS11010-017-3084-Z

21 January 2018

Gemcitabine and taxanes in metastatic breast cancer

1 reference

https://api.crossref.org/works/10.1007%2FS11010-017-3084-Z

21 January 2018

Functional roles of STAT family proteins: lessons from knockout mice

1 reference

https://api.crossref.org/works/10.1007%2FS11010-017-3084-Z

21 January 2018

Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells

1 reference

https://api.crossref.org/works/10.1007%2FS11010-017-3084-Z

21 January 2018

ErbB-2 kinase is required for constitutive stat 3 activation in malignant human lung epithelial cells

1 reference

https://api.crossref.org/works/10.1007%2FS11010-017-3084-Z

21 January 2018

Interference of glucocorticoids with apoptosis signaling and host-tumor interactions

1 reference

https://api.crossref.org/works/10.1007%2FS11010-017-3084-Z

21 January 2018

Glucocorticoids interfere with therapeutic efficacy of paclitaxel against human breast and ovarian xenograft tumors

1 reference

https://api.crossref.org/works/10.1007%2FS11010-017-3084-Z

21 January 2018

Cationic lipid-conjugated dexamethasone as a selective antitumor agent.

1 reference

https://api.crossref.org/works/10.1007%2FS11010-017-3084-Z

21 January 2018

WP1066 disrupts Janus kinase-2 and induces caspase-dependent apoptosis in acute myelogenous leukemia cells

1 reference

https://api.crossref.org/works/10.1007%2FS11010-017-3084-Z

21 January 2018

A novel inhibitor of the STAT3 pathway induces apoptosis in malignant glioma cells both in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1007%2FS11010-017-3084-Z

21 January 2018

Drug combination studies and their synergy quantification using the Chou-Talalay method

1 reference

https://api.crossref.org/works/10.1007%2FS11010-017-3084-Z

21 January 2018

A novel inhibitor of signal transducers and activators of transcription 3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T cells

1 reference

https://api.crossref.org/works/10.1007%2FS11010-017-3084-Z

21 January 2018

STAT3 acts as a co-activator of glucocorticoid receptor signaling

1 reference

https://api.crossref.org/works/10.1007%2FS11010-017-3084-Z

21 January 2018

Glucocorticoid-independent repression of tumor necrosis factor (TNF) alpha-stimulated interleukin (IL)-6 expression by the glucocorticoid receptor: a potential mechanism for protection against an excessive inflammatory response.

1 reference

https://api.crossref.org/works/10.1007%2FS11010-017-3084-Z

21 January 2018

Potential mechanism for the effects of dexamethasone on growth of androgen-independent prostate cancer.

1 reference

https://api.crossref.org/works/10.1007%2FS11010-017-3084-Z

21 January 2018

BCL-2 family members and the mitochondria in apoptosis

1 reference

https://api.crossref.org/works/10.1007%2FS11010-017-3084-Z

21 January 2018

Cross-talk between Akt, p53 and Mdm2: possible implications for the regulation of apoptosis

1 reference

https://api.crossref.org/works/10.1007%2FS11010-017-3084-Z

21 January 2018

Glucocorticoids inhibit the production of IL6 from monocytes, endothelial cells and fibroblasts

1 reference

https://api.crossref.org/works/10.1007%2FS11010-017-3084-Z

21 January 2018

Glucocorticoid receptor knockdown decreases the antioxidant protection of B16 melanoma cells: an endocrine system-related mechanism that compromises metastatic cell resistance to vascular endothelium-induced tumor cytotoxicity

1 reference

https://api.crossref.org/works/10.1007%2FS11010-017-3084-Z

21 January 2018

Irinotecan/gemcitabine combination chemotherapy in pancreatic cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/28585089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crosstalk between the interleukin-6 (IL-6)-JAK-STAT and the glucocorticoid-nuclear receptor pathway: synergistic activation of IL-6 response element by IL-6 and glucocorticoid

1 reference

https://pubmed.ncbi.nlm.nih.gov/28585089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucocorticoid cotreatment induces apoptosis resistance toward cancer therapy in carcinomas.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28585089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stat3-siRNA induces Fas-mediated apoptosis in vitro and in vivo in breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/28585089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of corticosteroid use on treatment of solid tumours

1 reference

https://pubmed.ncbi.nlm.nih.gov/28585089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug synergism: its detection and applications

1 reference

https://pubmed.ncbi.nlm.nih.gov/28585089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl-2 and Bcl-XL can differentially block chemotherapy-induced cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/28585089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of constitutive STAT3 activity sensitizes resistant non-Hodgkin's lymphoma and multiple myeloma to chemotherapeutic drug-mediated apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28585089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bortezomib plus dexamethasone as induction treatment prior to autologous stem cell transplantation in patients with newly diagnosed multiple myeloma: results of an IFM phase II study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28585089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

STAT-related transcription factors are constitutively activated in peripheral blood cells from acute leukemia patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/28585089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protection of murine bone marrow by dexamethasone during cytotoxic chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/28585089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11010-017-3084-Z

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28585089%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

release_254oubcapreh7k2ouamiykx3de

1 reference

https://api.fatcat.wiki/v0/release/254oubcapreh7k2ouamiykx3de

24 November 2022

based on heuristic

mapped directly with Wikidata item

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28585089%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

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