(Q48887111)

16 February 2018

title

Decreased neprilysin immunoreactivity in Alzheimer disease, but not in pathological aging. (English)

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16 February 2018

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Richard B Lipton

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16 February 2018

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Joe Verghese

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16 February 2018

Mindy J. Katz

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object named as

Mindy J Katz

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16 February 2018

author name string

Deng-Shun Wang

1

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16 February 2018

Peter Davies

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16 February 2018

Herman Buschke

5

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16 February 2018

Gail Kuslansky

6

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16 February 2018

Steven G Younkin

8

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16 February 2018

Chris Eckman

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16 February 2018

Dennis W Dickson

10

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16 February 2018

publication date

1 May 2005

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16 February 2018

Journal of Neuropathology & Experimental Neurology

published in

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16 February 2018

volume

64

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16 February 2018

issue

5

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16 February 2018

page(s)

378-385

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16 February 2018

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

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Identification of normal and pathological aging in prospectively studied nondemented elderly humans

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The levels of soluble versus insoluble brain Abeta distinguish Alzheimer's disease from normal and pathologic aging.

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Correlations of synaptic and pathological markers with cognition of the elderly

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Glycation and microglial reaction in lesions of Alzheimer's disease.

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The "nonamyloidogenic" p3 fragment (amyloid beta17-42) is a major constituent of Down's syndrome cerebellar preamyloid

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The cell biology of Alzheimer's disease: uncovering the secrets of secretases

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Beta-secretase protein and activity are increased in the neocortex in Alzheimer disease

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Elevated beta-secretase expression and enzymatic activity detected in sporadic Alzheimer disease

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Differential effects of proteases involved in intracellular degradation of amyloid beta-protein between detergent-soluble and -insoluble pools in CHO-695 cells

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Amyloid-beta peptide levels in brain are inversely correlated with insulysin activity levels in vivo

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Degradation of the Alzheimer's amyloid beta peptide by endothelin-converting enzyme

21 January 2018

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Alzheimer's disease beta-amyloid peptide is increased in mice deficient in endothelin-converting enzyme

21 January 2018

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Identification of the major Abeta1-42-degrading catabolic pathway in brain parenchyma: suppression leads to biochemical and pathological deposition

21 January 2018

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The neprilysin (NEP) family of zinc metalloendopeptidases: genomics and function

21 January 2018

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Beta-amyloid catabolism: roles for neprilysin (NEP) and other metallopeptidases?

21 January 2018

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Abeta-degrading endopeptidase, neprilysin, in mouse brain: synaptic and axonal localization inversely correlating with Abeta pathology

21 January 2018

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Region-specific reduction of A beta-degrading endopeptidase, neprilysin, in mouse hippocampus upon aging.

21 January 2018

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21 January 2018

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Relationship between beta amyloid peptide generating molecules and neprilysin in Alzheimer disease and normal brain

21 January 2018

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Development of an internally quenched fluorescent substrate selective for endothelin-converting enzyme-1.

21 January 2018

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Decreases in soluble alpha-synuclein in frontal cortex correlate with cognitive decline in the elderly.

21 January 2018

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Alpha-human atrial natriuretic peptide, carperitide, reduces infarct size but not arrhythmias after coronary occlusion/reperfusion in dogs

21 January 2018

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Contribution of asymmetric synapse loss to lateralizing clinical deficits in frontotemporal dementias.

21 January 2018

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Biochemical identification of the neutral endopeptidase family member responsible for the catabolism of amyloid beta peptide in the brain.

21 January 2018

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Amyloid beta protein (A beta) in Alzheimer's disease brain. Biochemical and immunocytochemical analysis with antibodies specific for forms ending at A beta 40 or A beta 42(43).

21 January 2018

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"Preclinical" AD revisited: neuropathology of cognitively normal older adults.

21 January 2018

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Neuropathology of cognitively normal elderly.

21 January 2018

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Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

21 January 2018

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Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

21 January 2018

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Oxidized neprilysin in aging and Alzheimer's disease brains

21 January 2018

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21 January 2018

Identifiers

DOI

10.1093/JNEN/64.5.378

1 reference

16 February 2018

PubMed ID

15892294

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16 February 2018