(Q48905746)

English

Pharmacokinetic and pharmacodynamic interaction of lorazepam and valproic acid in relation to UGT2B7 genetic polymorphism in healthy subjects

scientific article published on 8 August 2007

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scholarly article

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Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/17687269

Pharmacokinetic and pharmacodynamic interaction of lorazepam and valproic acid in relation to UGT2B7 genetic polymorphism in healthy subjects (English)

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/17687269

1 reference

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pharmacokinetics

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based on heuristic

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pharmacodynamics

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author name string

Chung JY

1

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/17687269

Cho JY

2

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/17687269

Yu KS

3

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/17687269

Kim JR

4

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/17687269

Lim KS

5

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/17687269

Sohn DR

6

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/17687269

Shin SG

7

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/17687269

Jang IJ

8

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Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/17687269

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publication date

8 August 2007

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Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/17687269

Clinical Pharmacology & Therapeutics

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Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/17687269

83

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Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/17687269

4

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Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/17687269

595-600

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Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/17687269

Disposition of lorazepam in Gilbert's syndrome: effects of fasting, feeding, and enterohepatic circulation.

1 reference

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Pharmacokinetic and -dynamic studies with a new anxiolytic, suriclone, utilizing EEG mapping and psychometry

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Concentration-effect relationships of valproic acid

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7 January 2021

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The effect of valproic acid on drug and steroid glucuronidation by expressed human UDP-glucuronosyltransferases

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Inhibitory effect of azole antifungal agents on the glucuronidation of lorazepam using rabbit liver microsomes in vitro

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Drug glucuronidation in humans

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7 January 2021

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Glucuronidation in humans. Pharmacogenetic and developmental aspects

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UGT1A1*28 polymorphism as a determinant of irinotecan disposition and toxicity

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7 January 2021

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Effect of the UGT2B15 genotype on the pharmacokinetics, pharmacodynamics, and drug interactions of intravenous lorazepam in healthy volunteers

1 reference

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7 January 2021

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Effect of valproate on the pharmacokinetics and pharmacodynamics of lorazepam

1 reference

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7 January 2021

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Coma probably induced by lorazepam-valproate interaction

1 reference

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7 January 2021

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Genetic polymorphism of UDP-glucuronosyltransferase 2B7 (UGT2B7) at amino acid 268: ethnic diversity of alleles and potential clinical significance

1 reference

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Evaluation of 3'-azido-3'-deoxythymidine, morphine, and codeine as probe substrates for UDP-glucuronosyltransferase 2B7 (UGT2B7) in human liver microsomes: specificity and influence of the UGT2B7*2 polymorphism

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7 January 2021

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Morphine glucuronide-to-morphine plasma ratios are unaffected by the UGT2B7 H268Y and UGT1A1*28 polymorphisms in cancer patients on chronic morphine therapy

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Altered kinetics and benzodiazepine sensitivity of a GABAA receptor subunit mutation [gamma 2(R43Q)] found in human epilepsy.

1 reference

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Evaluation of valproic acid fluoroimmunoassay and comparison with a gas liquid chromatographic method

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Stimulating music increases motor coordination in patients afflicted with Morbus Parkinson.

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7 January 2021

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Identifiers

10.1038/SJ.CLPT.6100324

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/17687269

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

16 February 2018

http://europepmc.org/abstract/MED/17687269

ResearchGate publication ID

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