(Q49015193)

English

Diabetes as a risk factor for Alzheimer's disease: insulin signalling impairment in the brain as an alternative model of Alzheimer's disease.

scientific article published in August 2011

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

17 February 2018

http://europepmc.org/abstract/MED/21787319

Diabetes as a risk factor for Alzheimer's disease: insulin signalling impairment in the brain as an alternative model of Alzheimer's disease. (English)

1 reference

Europe PubMed Central

PubMed publication ID

17 February 2018

http://europepmc.org/abstract/MED/21787319

Alzheimer's disease

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1 reference

based on heuristic

inferred from title

Christian Hölscher

1

1 reference

Europe PubMed Central

PubMed publication ID

17 February 2018

http://europepmc.org/abstract/MED/21787319

publication date

1 August 2011

1 reference

Europe PubMed Central

PubMed publication ID

17 February 2018

http://europepmc.org/abstract/MED/21787319

Biochemical Society Transactions

1 reference

Europe PubMed Central

PubMed publication ID

17 February 2018

http://europepmc.org/abstract/MED/21787319

39

1 reference

Europe PubMed Central

PubMed publication ID

17 February 2018

http://europepmc.org/abstract/MED/21787319

4

1 reference

Europe PubMed Central

PubMed publication ID

17 February 2018

http://europepmc.org/abstract/MED/21787319

891-897

1 reference

Europe PubMed Central

PubMed publication ID

17 February 2018

http://europepmc.org/abstract/MED/21787319

Amyloid, the presenilins and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1042%2FBST0390891

21 January 2018

Development of beta-amyloid-induced neurodegeneration in Alzheimer's disease and novel neuroprotective strategies.

1 reference

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21 January 2018

Hyperinsulinemia and risk of Alzheimer disease.

1 reference

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21 January 2018

Neurodegenerative disorders associated with diabetes mellitus

1 reference

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21 January 2018

Glucose metabolism and insulin receptor signal transduction in Alzheimer disease

1 reference

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21 January 2018

Insulin resistance, affective disorders, and Alzheimer's disease: review and hypothesis

1 reference

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21 January 2018

Treatment of insulin resistance in diabetes mellitus

1 reference

https://api.crossref.org/works/10.1042%2FBST0390891

21 January 2018

The role of insulin and insulin-like growth factor I in the molecular and cellular mechanisms underlying the pathology of Alzheimer's disease

1 reference

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21 January 2018

Hippocampal synaptic plasticity and glutamate receptor regulation: influences of diabetes mellitus

1 reference

https://api.crossref.org/works/10.1042%2FBST0390891

21 January 2018

Increased cortical atrophy in patients with Alzheimer's disease and type 2 diabetes mellitus

1 reference

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21 January 2018

Cognition and synaptic plasticity in diabetes mellitus

1 reference

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21 January 2018

Glucose, insulin and the brain: modulation of cognition and synaptic plasticity in health and disease: a preface

1 reference

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21 January 2018

Actions of exendin-4 therapy on cognitive function and hippocampal synaptic plasticity in mice fed a high-fat diet.

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21 January 2018

Insulin-like growth factor I and Alzheimer's disease: therapeutic prospects?

1 reference

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21 January 2018

Defects in IGF-1 receptor, insulin receptor and IRS-1/2 in Alzheimer's disease indicate possible resistance to IGF-1 and insulin signalling

1 reference

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21 January 2018

Common pathological processes in Alzheimer disease and type 2 diabetes: a review

1 reference

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21 January 2018

Insulin and insulin-like growth factor resistance with neurodegeneration in an adult chronic ethanol exposure model

1 reference

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21 January 2018

Insulin-like growth factor-I, cognition and brain aging

1 reference

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21 January 2018

Alzheimer-like changes in rat models of spontaneous diabetes

1 reference

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21 January 2018

Modulation of memory by insulin and glucose: neuropsychological observations in Alzheimer's disease

1 reference

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21 January 2018

Insulin and the insulin receptor in experimental models of learning and memory.

1 reference

https://api.crossref.org/works/10.1042%2FBST0390891

21 January 2018

A profile of impaired insulin degradation in relation to late-life cognitive decline: a preliminary investigation

1 reference

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21 January 2018

Intranasal insulin improves cognition and modulates beta-amyloid in early AD.

1 reference

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21 January 2018

Insulin resistance and Alzheimer's disease pathogenesis: potential mechanisms and implications for treatment

1 reference

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21 January 2018

Central nervous insulin resistance: a promising target in the treatment of metabolic and cognitive disorders?

1 reference

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21 January 2018

Incretins and their role in the management of diabetes

1 reference

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21 January 2018

Enhancing central nervous system endogenous GLP-1 receptor pathways for intervention in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1042%2FBST0390891

21 January 2018

Receptors for the incretin glucagon-like peptide-1 are expressed on neurons in the central nervous system.

1 reference

https://api.crossref.org/works/10.1042%2FBST0390891

21 January 2018

New roles for insulin-like hormones in neuronal signalling and protection: new hopes for novel treatments of Alzheimer's disease?

1 reference

https://api.crossref.org/works/10.1042%2FBST0390891

21 January 2018

Glucagon-like peptide-1 induces cell proliferation and pancreatic-duodenum homeobox-1 expression and increases endocrine cell mass in the pancreas of old, glucose-intolerant rats

1 reference

https://api.crossref.org/works/10.1042%2FBST0390891

21 January 2018

A novel neurotrophic property of glucagon-like peptide 1: a promoter of nerve growth factor-mediated differentiation in PC12 cells

1 reference

https://api.crossref.org/works/10.1042%2FBST0390891

21 January 2018

Glucagon-like peptide-1 decreases endogenous amyloid-beta peptide (Abeta) levels and protects hippocampal neurons from death induced by Abeta and iron.

1 reference

https://api.crossref.org/works/10.1042%2FBST0390891

21 January 2018

Evidence of GLP-1-mediated neuroprotection in an animal model of pyridoxine-induced peripheral sensory neuropathy

1 reference

https://api.crossref.org/works/10.1042%2FBST0390891

21 January 2018

Glucagon-like peptide-1 receptor is involved in learning and neuroprotection

1 reference

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21 January 2018

The diabetes drug liraglutide prevents degenerative processes in a mouse model of Alzheimer's disease.

1 reference

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21 January 2018

Practical issues in stem cell therapy for Alzheimer's disease.

1 reference

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21 January 2018

Val(8)GLP-1 rescues synaptic plasticity and reduces dense core plaques in APP/PS1 mice

1 reference

https://api.crossref.org/works/10.1042%2FBST0390891

21 January 2018

Role of the glucose-dependent insulinotropic polypeptide and its receptor in the central nervous system: therapeutic potential in neurological diseases.

1 reference

https://api.crossref.org/works/10.1042%2FBST0390891

21 January 2018

Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease.

1 reference

https://api.crossref.org/works/10.1042%2FBST0390891

21 January 2018

Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1042%2FBST0390891

21 January 2018

β-Amyloid impairs axonal BDNF retrograde trafficking

1 reference

https://api.crossref.org/works/10.1042%2FBST0390891

21 January 2018

Brain-derived neurotrophic factor in neurodegenerative diseases

1 reference

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21 January 2018

Neurotrophic factors--a tool for therapeutic strategies in neurological, neuropsychiatric and neuroimmunological diseases?

1 reference

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21 January 2018

Secretion of nerve growth factor from septum stimulates neurite outgrowth and release of the amyloid protein precursor of Alzheimer's disease from hippocampal explants

1 reference

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21 January 2018

Development of a non invasive NGF-based therapy for Alzheimer's disease.

1 reference

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21 January 2018

Cellular delivery of NGF does not alter the expression of beta-amyloid immunoreactivity in young or aged nonhuman primates.

1 reference

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21 January 2018

Hope for AD with NGF gene-therapy trial

1 reference

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21 January 2018

Nerve growth factor, neural stem cells and Alzheimer's disease

1 reference

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21 January 2018

Clinical gene therapy using recombinant adeno-associated virus vectors

1 reference

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21 January 2018

Differential effects of aging and insulin-like growth factor-1 on synapses in CA1 of rat hippocampus

1 reference

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21 January 2018

Beneficial effects of intrathecal IGF-1 administration in patients with amyotrophic lateral sclerosis

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21 January 2018

VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model

1 reference

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21 January 2018

Intrathecal transplantation of human neural stem cells overexpressing VEGF provide behavioral improvement, disease onset delay and survival extension in transgenic ALS mice

1 reference

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21 January 2018

Human neural stem cells over-expressing VEGF provide neuroprotection, angiogenesis and functional recovery in mouse stroke model

1 reference

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21 January 2018

In vitro study of GDNF release from biodegradable PLGA microspheres.

1 reference

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21 January 2018

Subcutaneous IGF-1 is not beneficial in 2-year ALS trial

1 reference

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21 January 2018

Adeno-associated virus-mediated gene delivery approaches for the treatment of CNS disorders

1 reference

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21 January 2018

Incretin analogues that have been developed to treat type 2 diabetes hold promise as a novel treatment strategy for Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1042%2FBST0390891

21 January 2018

Distribution and cellular localization of insulin-regulated aminopeptidase in the rat central nervous system

1 reference

https://api.crossref.org/works/10.1042%2FBST0390891

21 January 2018

Insulin and leptin induce Glut4 plasma membrane translocation and glucose uptake in a human neuronal cell line by a phosphatidylinositol 3-kinase- dependent mechanism.

1 reference

https://api.crossref.org/works/10.1042%2FBST0390891

21 January 2018

The insulin-regulated aminopeptidase IRAP is colocalised with GLUT4 in the mouse hippocampus--potential role in modulation of glucose uptake in neurones?

1 reference

https://api.crossref.org/works/10.1042%2FBST0390891

21 January 2018

Distinct molecular mechanisms and divergent endocytotic pathways of AMPA receptor internalization

1 reference

https://api.crossref.org/works/10.1042%2FBST0390891

21 January 2018

Recruitment of functional GABA(A) receptors to postsynaptic domains by insulin

1 reference

https://api.crossref.org/works/10.1042%2FBST0390891

21 January 2018

Increased glycogen synthase kinase-3 activity in diabetes- and obesity-prone C57BL/6J mice

1 reference

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21 January 2018

Comparative effects of GLP-1 and GIP on cAMP production, insulin secretion, and in vivo antidiabetic actions following substitution of Ala8/Ala2 with 2-aminobutyric acid.

1 reference

https://api.crossref.org/works/10.1042%2FBST0390891

21 January 2018

Pharmacological agents that directly modulate insulin secretion

1 reference

https://api.crossref.org/works/10.1042%2FBST0390891

21 January 2018

Calcium- and activity-dependent synaptic plasticity

1 reference

https://api.crossref.org/works/10.1042%2FBST0390891

21 January 2018

Foxa2 controls Pdx1 gene expression in pancreatic beta-cells in vivo.

1 reference

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21 January 2018

Insulinotropic glucagon-like peptide 1 agonists stimulate expression of homeodomain protein IDX-1 and increase islet size in mouse pancreas

1 reference

https://api.crossref.org/works/10.1042%2FBST0390891

21 January 2018

A family of cAMP-binding proteins that directly activate Rap1

1 reference

https://api.crossref.org/works/10.1042%2FBST0390891

21 January 2018

Expression of cAMP-regulated guanine nucleotide exchange factors in pancreatic beta-cells

1 reference

https://api.crossref.org/works/10.1042%2FBST0390891

21 January 2018

Glucagon-like peptide-1 promotes DNA synthesis, activates phosphatidylinositol 3-kinase and increases transcription factor pancreatic and duodenal homeobox gene 1 (PDX-1) DNA binding activity in beta (INS-1)-cells

1 reference

https://api.crossref.org/works/10.1042%2FBST0390891

21 January 2018

Identifiers

10.1042/BST0390891

1 reference

Europe PubMed Central

PubMed publication ID

17 February 2018

http://europepmc.org/abstract/MED/21787319

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

17 February 2018

http://europepmc.org/abstract/MED/21787319

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