(Q36529555)

14 August 2017

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title

Nerve growth factor, neural stem cells and Alzheimer's disease (English)

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14 August 2017

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Klaus Heese

1

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author name string

Jin Wei Low

series ordinal

2

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PubMed ID

16825799

14 August 2017

Noriko Inoue

series ordinal

3

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14 August 2017

4 July 2006

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14 August 2017

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14 August 2017

15

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14 August 2017

1

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14 August 2017

1-12

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The neurotrophins and neuropoietic cytokines: two families of growth factors acting on neural and hematopoietic cells

14 August 2017

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Neurotrophins: roles in neuronal development and function

21 January 2018

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Trk receptors: roles in neuronal signal transduction

21 January 2018

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Decreased trkA neurotrophin receptor expression in the parietal cortex of patients with Alzheimer's disease

21 January 2018

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p75NTR is positively promiscuous: novel partners and new insights

21 January 2018

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Increased proNGF levels in subjects with mild cognitive impairment and mild Alzheimer disease

21 January 2018

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Pro-NGF isolated from the human brain affected by Alzheimer's disease induces neuronal apoptosis mediated by p75NTR.

21 January 2018

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Alzheimer's disease: molecular understanding predicts amyloid-based therapeutics

21 January 2018

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Alzheimer's disease--an interactive perspective

21 January 2018

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A Drosophila gene encoding a protein resembling the human beta-amyloid protein precursor

21 January 2018

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apl-1, a Caenorhabditis elegans gene encoding a protein related to the human beta-amyloid protein precursor

21 January 2018

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The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth.

21 January 2018

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21 January 2018

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Mechanisms contributing to the deficits in hippocampal synaptic plasticity in mice lacking amyloid precursor protein

21 January 2018

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beta-Amyloid precursor protein metabolites and loss of neuronal Ca2+ homeostasis in Alzheimer's disease.

21 January 2018

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Alzheimer amyloid protein precursor complexes with brain GTP-binding protein G(o)

21 January 2018

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Ligand-dependent G protein coupling function of amyloid transmembrane precursor

21 January 2018

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Expression of the Alzheimer amyloid precursor gene transcripts in the human brain.

21 January 2018

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Immunohistochemical distribution of amyloid precursor protein during normal rat development.

21 January 2018

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Abeta-generating enzymes: recent advances in beta- and gamma-secretase research

21 January 2018

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A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60

21 January 2018

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The discrepancy between presenilin subcellular localization and gamma-secretase processing of amyloid precursor protein

21 January 2018

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The amyloid precursor protein (APP)-cytoplasmic fragment generated by gamma-secretase is rapidly degraded but distributes partially in a nuclear fraction of neurones in culture

21 January 2018

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Identification of a new presenilin-dependent zeta-cleavage site within the transmembrane domain of amyloid precursor protein.

21 January 2018

1 reference

Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments.

21 January 2018

1 reference

Normal and abnormal biology of the beta-amyloid precursor protein

21 January 2018

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Cell biology of protein misfolding: the examples of Alzheimer's and Parkinson's diseases

21 January 2018

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gamma-Secretase, Notch, Abeta and Alzheimer's disease: where do the presenilins fit in?

21 January 2018

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Roles of amyloid precursor protein and its fragments in regulating neural activity, plasticity and memory

21 January 2018

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APP processing and synaptic function

21 January 2018

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Nerve Growth Factor: Structure, Function and Therapeutic Implications for Alzheimers Disease

21 January 2018

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Reduction of cortical TrkA but not p75(NTR) protein in early-stage Alzheimer's disease.

21 January 2018

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The role of nerve growth factor receptors in cholinergic basal forebrain degeneration in prodromal Alzheimer disease

21 January 2018

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Alzheimer-like neurodegeneration in aged antinerve growth factor transgenic mice

21 January 2018

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Beta-amyloid plaques in a model for sporadic Alzheimer's disease based on transgenic anti-nerve growth factor antibodies

21 January 2018

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Nerve growth factor and galantamine ameliorate early signs of neurodegeneration in anti-nerve growth factor mice.

21 January 2018

1 reference

Intranasal administration of nerve growth factor (NGF) rescues recognition memory deficits in AD11 anti-NGF transgenic mice

21 January 2018

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Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I

21 January 2018

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Kinesin-mediated axonal transport of a membrane compartment containing beta-secretase and presenilin-1 requires APP

21 January 2018

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Disruption of axonal transport and neuronal viability by amyloid precursor protein mutations in Drosophila.

21 January 2018

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21 January 2018

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The intracellular domain of the beta-amyloid precursor protein is stabilized by Fe65 and translocates to the nucleus in a notch-like manner

21 January 2018

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The gamma secretase-generated carboxyl-terminal domain of the amyloid precursor protein induces apoptosis via Tip60 in H4 cells

21 January 2018

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Direct visualization of the gamma secretase-generated carboxyl-terminal domain of the amyloid precursor protein: association with Fe65 and translocation to the nucleus

21 January 2018

1 reference

Role of 14-3-3gamma in FE65-dependent gene transactivation mediated by the amyloid beta-protein precursor cytoplasmic fragment

21 January 2018

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Kinesin-dependent axonal transport is mediated by the sunday driver (SYD) protein

21 January 2018

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Motor protein receptors: moonlighting on other jobs

21 January 2018

1 reference

Interaction of Alzheimer's beta -amyloid precursor family proteins with scaffold proteins of the JNK signaling cascade

21 January 2018

1 reference

JSAP1, a novel jun N-terminal protein kinase (JNK)-binding protein that functions as a Scaffold factor in the JNK signaling pathway

21 January 2018

1 reference

Interaction of a mitogen-activated protein kinase signaling module with the neuronal protein JIP3

21 January 2018

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Cargo of kinesin identified as JIP scaffolding proteins and associated signaling molecules

21 January 2018

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Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene

21 January 2018

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Signal transduction by the JNK group of MAP kinases

21 January 2018

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Phosphorylation-dependent scaffolding role of JSAP1/JIP3 in the ASK1-JNK signaling pathway. A new mode of regulation of the MAP kinase cascade

21 January 2018

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Involvement of c-Jun N-terminal kinase in amyloid precursor protein-mediated neuronal cell death.

21 January 2018

1 reference

Sunday Driver links axonal transport to damage signaling

21 January 2018

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Neurotoxic mechanisms caused by the Alzheimer's disease-linked Swedish amyloid precursor protein mutation: oxidative stress, caspases, and the JNK pathway

21 January 2018

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ShcB and ShcC activation by the Trk family of receptor tyrosine kinases

21 January 2018

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Signal transduction through tyrosine-phosphorylated C-terminal fragments of amyloid precursor protein via an enhanced interaction with Shc/Grb2 adaptor proteins in reactive astrocytes of Alzheimer's disease brain.

21 January 2018

1 reference

Evidence for a role of the nerve growth factor receptor TrkA in tyrosine phosphorylation and processing of beta-APP.

21 January 2018

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Tyrosine phosphorylation of the beta-amyloid precursor protein cytoplasmic tail promotes interaction with Shc

21 January 2018

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Anterograde axonal transport, transcytosis, and recycling of neurotrophic factors: the concept of trophic currencies in neural networks

21 January 2018

1 reference

Retrograde transport of neurotrophins: fact and function

21 January 2018

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Mechanisms of neurotrophin receptor vesicular transport

21 January 2018

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Role of p75 neurotrophin receptor in the neurotoxicity by beta-amyloid peptides and synergistic effect of inflammatory cytokines

21 January 2018

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Amyloid beta binds trimers as well as monomers of the 75-kDa neurotrophin receptor and activates receptor signaling

21 January 2018

1 reference

Characterization of the toxic mechanism triggered by Alzheimer's amyloid-beta peptides via p75 neurotrophin receptor in neuronal hybrid cells

21 January 2018

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Getting RIP'd Stunts Your Growth.

21 January 2018

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Low concentrations of aggregated beta-amyloid induce neurite formation via the neurotrophin receptor p75.

21 January 2018

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Mammalian neural stem cells

21 January 2018

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Stem cell biology of the central nervous system

21 January 2018

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Aging and neuronal replacement

21 January 2018

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Neurospheres: insights into neural stem cell biology

21 January 2018

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Neural stem cells and neurospheres--re-evaluating the relationship.

21 January 2018

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Adult neurogenesis in the mammalian central nervous system

21 January 2018

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Neurogenesis in the adult is involved in the formation of trace memories

21 January 2018

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Memory traces of trace memories: neurogenesis, synaptogenesis and awareness

21 January 2018

1 reference

Disruption of neurogenesis in the subventricular zone of adult mice, and in human cortical neuronal precursor cells in culture, by amyloid beta-peptide: implications for the pathogenesis of Alzheimer's disease.

21 January 2018

1 reference

Disruption of neurogenesis by amyloid beta-peptide, and perturbed neural progenitor cell homeostasis, in models of Alzheimer's disease.

21 January 2018

1 reference

Neural stem cells and cholinergic neurons: regulation by immunolesion and treatment with mitogens, retinoic acid, and nerve growth factor.

21 January 2018

1 reference

Alzheimer's disease and neural transplantation as prospective cell therapy.

21 January 2018

1 reference

Neurogenic effect of beta-amyloid peptide in the development of neural stem cells.

21 January 2018

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Progenitor cells from the adult mouse brain acquire a neuronal phenotype in response to beta-amyloid

21 January 2018

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Possible use of autologous stem cell therapies for Alzheimer's disease.

21 January 2018

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Activating stem cells may treat Alzheimer's

21 January 2018

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Soluble form of amyloid precursor protein regulates proliferation of progenitors in the adult subventricular zone.

21 January 2018

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Controlling neural stem cell division within the adult subventricular zone: an APPealing job.

21 January 2018

1 reference

Neural stem cells express melatonin receptors and neurotrophic factors: colocalization of the MT1 receptor with neuronal and glial markers

21 January 2018

1 reference

Human mesenchymal stem cell subpopulations express a variety of neuro-regulatory molecules and promote neuronal cell survival and neuritogenesis

21 January 2018

1 reference

Sequential activation of p75 and TrkB is involved in dendritic development of subventricular zone-derived neuronal progenitors in vitro

21 January 2018

1 reference

Neuronal replacement from endogenous precursors in the adult brain after stroke

21 January 2018

1 reference

Brain-derived neurotrophic factor promotes the survival of neurons arising from the adult rat forebrain subependymal zone

21 January 2018

1 reference

In vitro survival and differentiation of neurons derived from epidermal growth factor-responsive postnatal hippocampal stem cells: inducing effects of brain-derived neurotrophic factor

21 January 2018

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Proliferation and differentiation of neuronal stem cells regulated by nerve growth factor.

21 January 2018

1 reference

The p75 receptor is required for BDNF-induced differentiation of neural precursor cells.

21 January 2018

1 reference

Embryonic precursor cells that express Trk receptors: induction of different cell fates by NGF, BDNF, NT-3, and CNTF.

21 January 2018

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Regionally specific effects of BDNF on oligodendrocytes

21 January 2018

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NT-3-mediated TrkC receptor activation promotes proliferation and cell survival of rodent progenitor oligodendrocyte cells in vitro and in vivo

21 January 2018

1 reference

Trk A, B, and C are commonly expressed in human astrocytes and astrocytic gliomas but not by human oligodendrocytes and oligodendroglioma.

21 January 2018

1 reference

NT3 inhibits FGF2-induced neural progenitor cell proliferation via the PI3K/GSK3 pathway

21 January 2018

1 reference

Clonal and population analyses demonstrate that an EGF-responsive mammalian embryonic CNS precursor is a stem cell.

21 January 2018

1 reference

New therapies. New Alzheimer's treatments that may ease the mind

21 January 2018

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Immunotherapy for Alzheimer disease: the promise and the problem.

21 January 2018

1 reference

A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease

21 January 2018

1 reference

Hope for AD with NGF gene-therapy trial

21 January 2018

1 reference

Region-Specific Neurotrophin Imbalances in Alzheimer Disease

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1159/000094383

1 reference

release_qihldjkrefgopdpsfaftv5g6ni

14 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/qihldjkrefgopdpsfaftv5g6ni

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

16825799

1 reference

PubMed ID

16825799