(Q30858845)

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Direct visualization of the gamma secretase-generated carboxyl-terminal domain of the amyloid precursor protein: association with Fe65 and translocation to the nucleus

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scholarly article

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Europe PubMed Central

27 June 2017

Direct visualization of the gamma secretase-generated carboxyl-terminal domain of the amyloid precursor protein: association with Fe65 and translocation to the nucleus (English)

1 reference

Europe PubMed Central

27 June 2017

1 reference

based on heuristic

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author name string

Kinoshita A

1

1 reference

Europe PubMed Central

27 June 2017

Whelan CM

2

1 reference

Europe PubMed Central

27 June 2017

Smith CJ

3

1 reference

Europe PubMed Central

27 June 2017

Berezovska O

4

1 reference

Europe PubMed Central

27 June 2017

Hyman BT

5

1 reference

Europe PubMed Central

27 June 2017

language of work or name

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publication date

1 August 2002

1 reference

Europe PubMed Central

27 June 2017

Journal of Neurochemistry

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Europe PubMed Central

27 June 2017

82

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Europe PubMed Central

27 June 2017

839-847

1 reference

Europe PubMed Central

27 June 2017

4

1 reference

Europe PubMed Central

27 June 2017

Notch signaling

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01016.X

21 January 2018

Aspartate mutations in presenilin and gamma-secretase inhibitors both impair notch1 proteolysis and nuclear translocation with relative preservation of notch1 signaling

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01016.X

21 January 2018

Notch1 and amyloid precursor protein are competitive substrates for presenilin1-dependent gamma-secretase cleavage

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01016.X

21 January 2018

The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01016.X

21 January 2018

Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01016.X

21 January 2018

A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01016.X

21 January 2018

APP-BP1, a novel protein that binds to the carboxyl-terminal region of the amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01016.X

21 January 2018

The amyloid precursor protein (APP)-cytoplasmic fragment generated by gamma-secretase is rapidly degraded but distributes partially in a nuclear fraction of neurones in culture

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01016.X

21 January 2018

A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01016.X

21 January 2018

Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01016.X

21 January 2018

The regions of the Fe65 protein homologous to the phosphotyrosine interaction/phosphotyrosine binding domain of Shc bind the intracellular domain of the Alzheimer's amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01016.X

21 January 2018

The gamma -secretase-cleaved C-terminal fragment of amyloid precursor protein mediates signaling to the nucleus

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01016.X

21 January 2018

Association of a novel human FE65-like protein with the cytoplasmic domain of the beta-amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01016.X

21 January 2018

The disabled 1 phosphotyrosine-binding domain binds to the internalization signals of transmembrane glycoproteins and to phospholipids

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01016.X

21 January 2018

The intracellular domain of the beta-amyloid precursor protein is stabilized by Fe65 and translocates to the nucleus in a notch-like manner

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01016.X

21 January 2018

Demonstration by fluorescence resonance energy transfer of a close association between activated MAP kinase and neurofibrillary tangles: implications for MAP kinase activation in Alzheimer disease.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01016.X

21 January 2018

Membrane association and protein conformation of alpha-synuclein in intact neurons. Effect of Parkinson's disease-linked mutations

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01016.X

21 January 2018

The intracellular cytoplasmic domain of the Alzheimer's disease amyloid precursor protein interacts with phosphotyrosine-binding domain proteins in the yeast two-hybrid system

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01016.X

21 January 2018

gamma -Secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01016.X

21 January 2018

Cell surface presenilin-1 participates in the gamma-secretase-like proteolysis of Notch

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01016.X

21 January 2018

Presenilin-dependent gamma-secretase processing of beta-amyloid precursor protein at a site corresponding to the S3 cleavage of Notch

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01016.X

21 January 2018

Jun NH2-terminal kinase (JNK) interacting protein 1 (JIP1) binds the cytoplasmic domain of the Alzheimer's beta-amyloid precursor protein (APP).

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01016.X

21 January 2018

Proteolytic release and nuclear translocation of Notch-1 are induced by presenilin-1 and impaired by pathogenic presenilin-1 mutations

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01016.X

21 January 2018

A loss of function mutation of presenilin-2 interferes with amyloid beta-peptide production and notch signaling

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01016.X

21 January 2018

Presenilin is required for activity and nuclear access of Notch in Drosophila

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01016.X

21 January 2018

Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01016.X

21 January 2018

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01016.X

21 January 2018

Neurogenic phenotypes and altered Notch processing in Drosophila Presenilin mutants.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01016.X

21 January 2018

Characterization of a presenilin-mediated amyloid precursor protein carboxyl-terminal fragment gamma. Evidence for distinct mechanisms involved in gamma -secretase processing of the APP and Notch1 transmembrane domains

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01016.X

21 January 2018

PAT1, a microtubule-interacting protein, recognizes the basolateral sorting signal of amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01016.X

21 January 2018

Identifiers

10.1046/J.1471-4159.2002.01016.X

1 reference

Europe PubMed Central

27 June 2017

1 reference

Europe PubMed Central

27 June 2017

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