(Q33289346)

English

Jun NH2-terminal kinase (JNK) interacting protein 1 (JIP1) binds the cytoplasmic domain of the Alzheimer's beta-amyloid precursor protein (APP).

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

25 July 2017

Jun NH2-terminal kinase (JNK) interacting protein 1 (JIP1) binds the cytoplasmic domain of the Alzheimer's beta-amyloid precursor protein (APP). (English)

1 reference

Europe PubMed Central

PubMed publication ID

25 July 2017

Alzheimer's disease

0 references

Meir H Scheinfeld

object named as

Meir H Scheinfeld

1

0 references

object named as

Peter A Lopez

4

0 references

Luciano D'Adamio

object named as

Luciano D'Adamio

6

0 references

author name string

Roberta Roncarati

2

1 reference

Europe PubMed Central

PubMed publication ID

25 July 2017

Pasquale Vito

3

1 reference

Europe PubMed Central

PubMed publication ID

25 July 2017

Mona Abdallah

5

1 reference

Europe PubMed Central

PubMed publication ID

25 July 2017

language of work or name

0 references

publication date

27 November 2001

1 reference

Europe PubMed Central

PubMed publication ID

25 July 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

25 July 2017

277

1 reference

Europe PubMed Central

PubMed publication ID

25 July 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

25 July 2017

3767-3775

1 reference

Europe PubMed Central

PubMed publication ID

25 July 2017

Amyloid, the presenilins and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Mutant genes in familial Alzheimer's disease and transgenic models

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Amyloid beta-protein and the genetics of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Cellular processing of beta-amyloid precursor protein and the genesis of amyloid beta-peptide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Candidate gene for the chromosome 1 familial Alzheimer's disease locus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

The presenilins in Alzheimer's disease--proteolysis holds the key.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

A loss of function mutation of presenilin-2 interferes with amyloid beta-peptide production and notch signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Intramembrane proteolysis by presenilins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

The Role of presenilins in gamma-secretase activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

The beta-amyloid precursor protein functions as a cytosolic anchoring site that prevents Fe65 nuclear translocation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Requirement of the familial Alzheimer's disease gene PS2 for apoptosis. Opposing effect of ALG-3

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Participation of presenilin 2 in apoptosis: enhanced basal activity conferred by an Alzheimer mutation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Are presenilins intramembrane-cleaving proteases? Implications for the molecular mechanism of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

A cytoplasmic inhibitor of the JNK signal transduction pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Fas preassociation required for apoptosis signaling and dominant inhibition by pathogenic mutations

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Fluorescence resonance energy transfer analysis of cell surface receptor interactions and signaling using spectral variants of the green fluorescent protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Polarized secretion of beta-amyloid precursor protein and amyloid beta-peptide in MDCK cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Cloning of AIP1, a novel protein that associates with the apoptosis-linked gene ALG-2 in a Ca2+-dependent reaction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

The disabled 1 phosphotyrosine-binding domain binds to the internalization signals of transmembrane glycoproteins and to phospholipids

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

The regions of the Fe65 protein homologous to the phosphotyrosine interaction/phosphotyrosine binding domain of Shc bind the intracellular domain of the Alzheimer's amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Interaction of the phosphotyrosine interaction/phosphotyrosine binding-related domains of Fe65 with wild-type and mutant Alzheimer's beta-amyloid precursor proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

A mammalian scaffold complex that selectively mediates MAP kinase activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Fluorescence Energy Transfer as a Spectroscopic Ruler

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

New insights into the control of MAP kinase pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Mammalian MAP kinase signalling cascades

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Neurodegenerative tauopathies

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Apoptosis decision cascades and neuronal degeneration in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

p38 kinase is activated in the Alzheimer's disease brain.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Activation of neuronal extracellular receptor kinase (ERK) in Alzheimer disease links oxidative stress to abnormal phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Activation and redistribution of c-jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

JNK activation is associated with intracellular beta-amyloid accumulation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Phosphorylation of microtubule-associated protein tau by stress-activated protein kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Differential activation of neuronal ERK, JNK/SAPK and p38 in Alzheimer disease: the 'two hit' hypothesis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Signal transduction by the JNK group of MAP kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

MKK7 is an essential component of the JNK signal transduction pathway activated by proinflammatory cytokines

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

The JIP group of mitogen-activated protein kinase scaffold proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Interaction of a mitogen-activated protein kinase signaling module with the neuronal protein JIP3

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Requirement of the JIP1 scaffold protein for stress-induced JNK activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

The reelin receptor ApoER2 recruits JNK-interacting proteins-1 and -2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

IB1, a JIP-1-related nuclear protein present in insulin-secreting cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

The gene MAPK8IP1, encoding islet-brain-1, is a candidate for type 2 diabetes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

IB1 reduces cytokine-induced apoptosis of insulin-secreting cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Cargo of kinesin identified as JIP scaffolding proteins and associated signaling molecules

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Proteolytic processing of the Alzheimer's disease amyloid precursor protein within its cytoplasmic domain by caspase-like proteases.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Alternative, non-secretase processing of Alzheimer's beta-amyloid precursor protein during apoptosis by caspase-6 and -8.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Caspase-6 role in apoptosis of human neurons, amyloidogenesis, and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Kunitz protease inhibitor-containing amyloid beta protein precursor immunoreactivity in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Generation of an apoptotic intracellular peptide by gamma-secretase cleavage of Alzheimer's amyloid beta protein precursor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Toward a comprehensive theory for Alzheimer's disease. Hypothesis: Alzheimer's disease is caused by the cerebral accumulation and cytotoxicity of amyloid beta-protein.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Filamentous nerve cell inclusions in neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108357200

21 January 2018

Identifiers

10.1074/JBC.M108357200

1 reference

Europe PubMed Central

PubMed publication ID

25 July 2017

release_nocvmemigrdt3adai7f6orsa4m

1 reference

https://api.fatcat.wiki/v0/release/nocvmemigrdt3adai7f6orsa4m

24 November 2022

based on heuristic

mapped directly with Wikidata item

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

25 July 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q33289346&oldid=2081896204"