(Q49016618)

17 February 2018

title

Quinoprotein adducts accumulate in the substantia nigra of aged rats and correlate with dopamine-induced toxicity in SH-SY5Y cells. (English)

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17 February 2018

1 reference

Na Wang

1

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17 February 2018

Yan Wang

2

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17 February 2018

Guohua Yu

3

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17 February 2018

Chonggang Yuan

4

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17 February 2018

Jiyan Ma

5

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17 February 2018

publication date

22 July 2011

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17 February 2018

published in

Neurochemical Research

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17 February 2018

volume

36

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17 February 2018

issue

11

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17 February 2018

page(s)

2169-2175

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17 February 2018

Epidemiology of Parkinson's disease

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Reduced vesicular storage of dopamine causes progressive nigrostriatal neurodegeneration

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Unregulated cytosolic dopamine causes neurodegeneration associated with oxidative stress in mice

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Interplay between cytosolic dopamine, calcium, and alpha-synuclein causes selective death of substantia nigra neurons

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Dopamine oxidation alters mitochondrial respiration and induces permeability transition in brain mitochondria: implications for Parkinson's disease

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Dopamine covalently modifies and functionally inactivates parkin

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Protein kinase C delta negatively regulates tyrosine hydroxylase activity and dopamine synthesis by enhancing protein phosphatase-2A activity in dopaminergic neurons

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Sulforaphane as an inducer of glutathione prevents oxidative stress-induced cell death in a dopaminergic-like neuroblastoma cell line

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Vulnerability to DNA damage in the aging rat substantia nigra: a study with the comet assay

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Novel cell death signaling pathways in neurotoxicity models of dopaminergic degeneration: relevance to oxidative stress and neuroinflammation in Parkinson's disease

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Mitochondrial dysfunction mediated by quinone oxidation products of dopamine: Implications in dopamine cytotoxicity and pathogenesis of Parkinson's disease

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12 December 2020

Tyrosine hydroxylase in rat brain dopaminergic nerve terminals. Multiple-site phosphorylation in vivo and in synaptosomes

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12 December 2020

Inhibition of glutamate transport in synaptosomes by dopamine oxidation and reactive oxygen species.

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12 December 2020

Mechanisms of dopamine-induced cell death in cultured rat forebrain neurons: interactions with and differences from glutamate-induced cell death

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12 December 2020

Modification of dopamine transporter function: effect of reactive oxygen species and dopamine.

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12 December 2020

Tyrosine hydroxylase is inactivated by catechol-quinones and converted to a redox-cycling quinoprotein: possible relevance to Parkinson's disease.

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12 December 2020

Oxidative pathways for catecholamines in the genesis of neuromelanin and cytotoxic quinones

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12 December 2020

Specific detection of quinoproteins by redox-cycling staining

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12 December 2020

L-DOPA-quinone inactivates tryptophan hydroxylase and converts the enzyme to a redox-cycling quinoprotein

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10.1007/S11064-011-0541-Z

Identifiers

DOI

1 reference

17 February 2018

Dimensions Publication ID

1030391668

0 references

1 reference

17 February 2018