(Q49040893)

18 February 2018

title

Tauroursodeoxycholic acid inhibits experimental colitis by preventing early intestinal epithelial cell death. (English)

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18 February 2018

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18 February 2018

Roosmarijn Vandenbroucke

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18 February 2018

Yves-Paul Vandewynckel

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18 February 2018

Lindsey Devisscher

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Lindsey Devisscher

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Peter Vandenabeele

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Peter Vandenabeele

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author name string

Lien Van den Bossche

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18 February 2018

Pieter Hindryckx

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18 February 2018

Claude Cuvelier

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18 February 2018

Brigitta M Brinkman

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18 February 2018

Claude Libert

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18 February 2018

Martine De Vos

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18 February 2018

publication date

13 October 2014

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18 February 2018

published in

Laboratory Investigation

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18 February 2018

volume

94

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18 February 2018

issue

12

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18 February 2018

page(s)

1419-1430

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18 February 2018

https://scigraph.springernature.com/pub.10.1038/labinvest.2014.117

exact match

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cites work

Regulation of apoptosis during homeostasis and disease in the intestinal epithelium

1 reference

12 December 2020

Muc2-deficient mice spontaneously develop colitis, indicating that MUC2 is critical for colonic protection

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12 December 2020

Tauroursodeoxycholic acid (TUDCA) protects photoreceptors from cell death after experimental retinal detachment

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12 December 2020

Damage-induced apoptosis in intestinal epithelia from bcl-2-null and bax-null mice: investigations of the mechanistic determinants of epithelial apoptosis in vivo

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12 December 2020

Apoptosis of colorectal adenocarcinoma (COLO 201) by tumour necrosis factor-alpha (TNF-alpha) and/or interferon-gamma (IFN-gamma), resulting from down-modulation of Bcl-2 expression

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12 December 2020

p53 and PUMA independently regulate apoptosis of intestinal epithelial cells in patients and mice with colitis

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12 December 2020

Increased proliferation and apoptosis of colonic epithelial cells in dextran sulfate sodium-induced colitis in rats

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12 December 2020

The role of membrane cholesterol in determining bile acid cytotoxicity and cytoprotection of ursodeoxycholic acid

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12 December 2020

p53 mediates TNF-induced epithelial cell apoptosis in IBD.

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12 December 2020

Tauroursodeoxycholic acid prevents Bax-induced membrane perturbation and cytochrome C release in isolated mitochondria

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12 December 2020

Higher fecal bile acid hydrophobicity is associated with exacerbation of dextran sodium sulfate colitis in mice

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12 December 2020

The unfolded protein response and chemical chaperones reduce protein misfolding and colitis in mice

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12 December 2020

Bile acid modulates transepithelial permeability via the generation of reactive oxygen species in the Caco-2 cell line

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12 December 2020

Connecting dysbiosis, bile-acid dysmetabolism and gut inflammation in inflammatory bowel diseases.

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12 December 2020

Gut microbiota affects sensitivity to acute DSS-induced colitis independently of host genotype

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12 December 2020

Epithelial barrier function in vivo is sustained despite gaps in epithelial layers

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12 December 2020

Matrix metalloproteinase 13 modulates intestinal epithelial barrier integrity in inflammatory diseases by activating TNF.

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12 December 2020

iNOS-dependent increase in colonic mucus thickness in DSS-colitic rats

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12 December 2020

Measurement of Cutaneous Inflammation: Estimation of Neutrophil Content with an Enzyme Marker

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12 December 2020

Bile acid transporters: structure, function, regulation and pathophysiological implications

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12 December 2020

Bacterial translocation from the gastrointestinal tract

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12 December 2020

Local barrier dysfunction identified by confocal laser endomicroscopy predicts relapse in inflammatory bowel disease

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12 December 2020

Bile acids modulate tight junction structure and barrier function of Caco-2 monolayers via EGFR activation.

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12 December 2020

Structure-function analysis of the tertiary bile acid TUDCA for the resolution of endoplasmic reticulum stress in intestinal epithelial cells

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12 December 2020

Positive role of CCAAT/enhancer-binding protein homologous protein, a transcription factor involved in the endoplasmic reticulum stress response in the development of colitis

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12 December 2020

Signaling pathway via TNF-alpha/NF-kappaB in intestinal epithelial cells may be directly involved in colitis-associated carcinogenesis

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12 December 2020

alpha5beta1 integrin protects intestinal epithelial cells from apoptosis through a phosphatidylinositol 3-kinase and protein kinase B-dependent pathway

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12 December 2020

Increased apoptosis and decreased proliferation of colonic epithelium in dextran sulfate sodium-induced colitis in mice

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12 December 2020

Bile acids: regulation of apoptosis by ursodeoxycholic acid

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12 December 2020

α5 β1-integrins are sensors for tauroursodeoxycholic acid in hepatocytes.

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12 December 2020

Primary cultures of fully differentiated and pure human intestinal epithelial cells

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12 December 2020

Modulation of barrier function during Fas-mediated apoptosis in human intestinal epithelial cells

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12 December 2020

10.1038/LABINVEST.2014.117

Identifiers

DOI

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18 February 2018

Dimensions Publication ID

1013871757

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18 February 2018