(Q49544932)

21 February 2018

title

Altered Epigenetic Mechanisms in Thyroid Cancer Subtypes (English)

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21 February 2018

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3

Fereidoun Azizi

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21 February 2018

Maryam Zarkesh

1

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21 February 2018

Azita Zadeh-Vakili

2

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21 February 2018

Forough Foroughi

4

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21 February 2018

Maziar Mohammad Akhavan

5

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21 February 2018

Mehdi Hedayati

6

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21 February 2018

publication date

6 October 2017

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21 February 2018

Molecular Diagnosis and Therapy

published in

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21 February 2018

volume

22

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21 February 2018

issue

1

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21 February 2018

page(s)

41-56

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21 February 2018

Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells

cites work

1 reference

12 December 2020

MicroRNA-96 plays an oncogenic role by targeting FOXO1 and regulating AKT/FOXO1/Bim pathway in papillary thyroid carcinoma cells

1 reference

12 December 2020

Analysis of loss of heterozygsity effect on thyroid tumor with oxyphilia cell locus in familial non medullary thyroid carcinoma in Iranian families

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12 December 2020

The role of microRNA genes in papillary thyroid carcinoma

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12 December 2020

Reactivation of the silenced thyroid hormone receptor β gene expression delays thyroid tumor progression

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12 December 2020

The RASSF1A tumor suppressor

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12 December 2020

Novel histone deacetylase inhibitors in clinical trials as anti-cancer agents

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12 December 2020

Poorly differentiated and anaplastic thyroid cancer

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12 December 2020

Methylation status of genes in papillary thyroid carcinoma

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12 December 2020

Methylation Markers for Early Detection and Differentiation of Follicular Thyroid Cancer Subtypes

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12 December 2020

Global levels of histone modifications predict prognosis in different cancers

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12 December 2020

miR-142-3p down-regulation contributes to thyroid follicular tumorigenesis by targeting ASH1L and MLL1.

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12 December 2020

Integrated genomic characterization of papillary thyroid carcinoma

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12 December 2020

Cytotoxic activity of the histone deacetylase inhibitor panobinostat (LBH589) in anaplastic thyroid cancer in vitro and in vivo

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12 December 2020

PTEN promoter methylation in sporadic thyroid carcinomas

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12 December 2020

Genetic alterations and their relationship in the phosphatidylinositol 3-kinase/Akt pathway in thyroid cancer

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12 December 2020

Germline RET mutations in exons 10 and 11: an Iranian survey of 57 medullary thyroid carcinoma cases

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12 December 2020

Downregulation of Rap1GAP through epigenetic silencing and loss of heterozygosity promotes invasion and progression of thyroid tumors

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12 December 2020

MicroRNA-146a targets PRKCE to modulate papillary thyroid tumor development

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12 December 2020

Global histone modification patterns predict risk of prostate cancer recurrence

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12 December 2020

In vivo imaging of functional targeting of miR-221 in papillary thyroid carcinoma

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12 December 2020

Concomitant RAS, RET/PTC, or BRAF mutations in advanced stage of papillary thyroid carcinoma.

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12 December 2020

Targeted therapy of thyroid cancer.

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12 December 2020

MiR-129-5p is down-regulated and involved in the growth, apoptosis and migration of medullary thyroid carcinoma cells through targeting RET.

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12 December 2020

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12 December 2020

High prevalence and mutual exclusivity of genetic alterations in the phosphatidylinositol-3-kinase/akt pathway in thyroid tumors

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12 December 2020

Molecular analysis of the RET proto-oncogene key exons in patients with medullary thyroid carcinoma: a comprehensive study of the Iranian population.

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12 December 2020

MicroRNAs (miR)-221 and miR-222, both overexpressed in human thyroid papillary carcinomas, regulate p27Kip1 protein levels and cell cycle

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12 December 2020

Association of aberrant methylation of tumor suppressor genes with tumor aggressiveness and BRAF mutation in papillary thyroid cancer

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12 December 2020

Cancer statistics, 2010

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12 December 2020

Analysis of BRAF(V600E) mutation and DNA methylation improves the diagnostics of thyroid fine needle aspiration biopsies

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12 December 2020

Frequent epigenetic silencing of the CpG island promoter of RASSF1A in thyroid carcinoma.

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12 December 2020

PI3K/AKT Pathway and Its Mediators in Thyroid Carcinomas

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12 December 2020

Levels of histone acetylation in thyroid tumors

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12 December 2020

Lack of therapeutic effect of the histone deacetylase inhibitor vorinostat in patients with metastatic radioiodine-refractory thyroid carcinoma

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12 December 2020

MicroRNAs in the thyroid.

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12 December 2020

CpG island methylation of tumor-related promoters occurs preferentially in undifferentiated carcinoma

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12 December 2020

Approach to the patient with anaplastic thyroid carcinoma

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12 December 2020

Hypermethylation of the CDKN2/p16INK4A promotor in thyroid carcinogenesis

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12 December 2020

Targeting DNA methylation for epigenetic therapy

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12 December 2020

Association of PTEN gene methylation with genetic alterations in the phosphatidylinositol 3-kinase/AKT signaling pathway in thyroid tumors.

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12 December 2020

MicroRNA-145 inhibits human papillary cancer TPC1 cell proliferation by targeting DUSP6

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12 December 2020

RAS point mutations and PAX8-PPAR gamma rearrangement in thyroid tumors: evidence for distinct molecular pathways in thyroid follicular carcinoma.

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12 December 2020

Differential miRNA expression defines migration and reduced apoptosis in follicular thyroid carcinomas

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12 December 2020

Genome-wide appraisal of thyroid cancer progression.

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12 December 2020

RET proto oncogene mutation detection and medullary thyroid carcinoma prevention

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12 December 2020

International patterns and trends in thyroid cancer incidence, 1973-2002

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12 December 2020

Thyroid cancer mortality and incidence: a global overview.

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12 December 2020

Highly prevalent genetic alterations in receptor tyrosine kinases and phosphatidylinositol 3-kinase/akt and mitogen-activated protein kinase pathways in anaplastic and follicular thyroid cancers

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12 December 2020

Effect of BRAFV600E mutation on transcription and post-transcriptional regulation in a papillary thyroid carcinoma model

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12 December 2020

Deregulation of microRNA expression in thyroid neoplasias

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12 December 2020

Mitogen-inducible gene-6 is a multifunctional adaptor protein with tumor suppressor-like activity in papillary thyroid cancer

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12 December 2020

Molecular pathogenesis and mechanisms of thyroid cancer

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12 December 2020

The miR-221/222 cluster, miR-10b and miR-92a are highly upregulated in metastatic minimally invasive follicular thyroid carcinoma

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12 December 2020

DNA methylation of MAPK signal-inhibiting genes in papillary thyroid carcinoma

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12 December 2020

Down-regulation of the miR-25 and miR-30d contributes to the development of anaplastic thyroid carcinoma targeting the polycomb protein EZH2.

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12 December 2020

A phase II trial of valproic acid in patients with advanced, radioiodine-resistant thyroid cancers of follicular cell origin

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12 December 2020

Analysis of deregulated miRNAs is helpful to distinguish poorly differentiated thyroid carcinoma from papillary thyroid carcinoma

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12 December 2020

DNA methylation state of the galectin-3 gene represents a potential new marker of thyroid malignancy.

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12 December 2020

Histone deacetylation of NIS promoter underlies BRAF V600E-promoted NIS silencing in thyroid cancer

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12 December 2020

BRAF(V600E) Mutation, RET/PTC1 and PAX8-PPAR Gamma Rearrangements in Follicular Epithelium Derived Thyroid Lesions - Institutional Experience and Literature Review

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12 December 2020

Loss of the CBX7 gene expression correlates with a highly malignant phenotype in thyroid cancer

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12 December 2020

Methylation of the thyroid-stimulating hormone receptor gene in epithelial thyroid tumors: a marker of malignancy and a cause of gene silencing

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12 December 2020

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12 December 2020

Epigenetics modifications and therapeutic prospects in human thyroid cancer.

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12 December 2020

ZNF367 inhibits cancer progression and is targeted by miR-195

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12 December 2020

DKK3 is a potential tumor suppressor gene in papillary thyroid carcinoma

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12 December 2020

MicroRNA Deregulation in Anaplastic Thyroid Cancer Biology

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12 December 2020

Epigenetic silencing of TTF-1/NKX2-1 through DNA hypermethylation and histone H3 modulation in thyroid carcinomas

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12 December 2020

DNA methylation signatures identify biologically distinct thyroid cancer subtypes.

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12 December 2020

MicroRNA profile of poorly differentiated thyroid carcinomas: new diagnostic and prognostic insights

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12 December 2020

Histone deacetylase inhibitors upregulate Rap1GAP and inhibit Rap activity in thyroid tumor cells

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12 December 2020

Histone deacetylase inhibitors in cancer therapy

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12 December 2020

miR-145 suppresses thyroid cancer growth and metastasis and targets AKT3.

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12 December 2020

DNA hypermethylation status of multiple genes in papillary thyroid carcinomas

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12 December 2020

MicroRNA signature distinguishes the degree of aggressiveness of papillary thyroid carcinoma

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12 December 2020

Histone deacetylase inhibitors induce thyroid cancer-specific apoptosis through proteasome-dependent inhibition of TRAIL degradation.

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12 December 2020

Genome-wide methylation patterns in papillary thyroid cancer are distinct based on histological subtype and tumor genotype.

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12 December 2020

Genomic and transcriptomic hallmarks of poorly differentiated and anaplastic thyroid cancers.

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12 December 2020

Regulation of autophagy by miR-30d impacts sensitivity of anaplastic thyroid carcinoma to cisplatin

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12 December 2020

MiR-618 inhibits anaplastic thyroid cancer by repressing XIAP in one ATC cell line

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12 December 2020

DNA methylation profiling of well-differentiated thyroid cancer uncovers markers of recurrence free survival.

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12 December 2020

MicroRNA profiles in familial and sporadic medullary thyroid carcinoma: preliminary relationships with RET status and outcome

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12 December 2020

Lack of mutations in the thyroid hormone receptor (TR) alpha and beta genes but frequent hypermethylation of the TRbeta gene in differentiated thyroid tumors.

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12 December 2020

Methylation of DACT2 promotes papillary thyroid cancer metastasis by activating Wnt signaling

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12 December 2020

Valproic acid as epigenetic cancer drug: preclinical, clinical and transcriptional effects on solid tumors

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12 December 2020

Poorly differentiated carcinoma of the thyroid: validation of the Turin proposal and analysis of IMP3 expression.

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12 December 2020

Down-regulation of miR-181b promotes apoptosis by targeting CYLD in thyroid papillary cancer

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12 December 2020

Identification of RASAL1 as a major tumor suppressor gene in thyroid cancer

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12 December 2020

Effect of ret/PTC 1 rearrangement on transcription and post-transcriptional regulation in a papillary thyroid carcinoma model

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12 December 2020

MicroRNA deregulation in human thyroid papillary carcinomas.

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12 December 2020

Medullary thyroid cancer: management guidelines of the American Thyroid Association

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12 December 2020

Predominant RET Germline Mutations in Exons 10, 11, and 16 in Iranian Patients with Hereditary Medullary Thyroid Carcinoma

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12 December 2020

DNA methylation in thyroid tumorigenesis

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12 December 2020

Non-Coding RNAs in Thyroid Cancer

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12 December 2020

Cancer is a preventable disease that requires major lifestyle changes

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12 December 2020

Disruption of cell-type-specific methylation at the Maspin gene promoter is frequently involved in undifferentiated thyroid cancers

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12 December 2020

Oncogenic AKAP9-BRAF fusion is a novel mechanism of MAPK pathway activation in thyroid cancer

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12 December 2020

MiR-129-5p is required for histone deacetylase inhibitor-induced cell death in thyroid cancer cells

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12 December 2020

Prognosis and prognostic factors of follicular carcinoma in Japan: importance of postoperative pathological examination

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12 December 2020

Chromobox protein homologue 7 protein, with decreased expression in human carcinomas, positively regulates E-cadherin expression by interacting with the histone deacetylase 2 protein

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12 December 2020

Molecular mechanisms of antiseizure drug activity at GABAA receptors

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12 December 2020

MiR-20a is upregulated in anaplastic thyroid cancer and targets LIMK1.

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12 December 2020

MicroRNA expression profiling of thyroid tumors: biological significance and diagnostic utility

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12 December 2020

Enhancer of zeste homolog 2 overexpression has a role in the development of anaplastic thyroid carcinomas

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12 December 2020

Genome-wide alterations in gene methylation by the BRAF V600E mutation in papillary thyroid cancer cells

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12 December 2020

A limited set of human MicroRNA is deregulated in follicular thyroid carcinoma.

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12 December 2020

Continued rapid increase in thyroid cancer incidence in california: trends by patient, tumor, and neighborhood characteristics

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12 December 2020

Personalized therapy in patients with anaplastic thyroid cancer: targeting genetic and epigenetic alterations

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12 December 2020

New targets and therapeutic approaches for endocrine malignancies

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12 December 2020

Overexpression of miR-10a and miR-375 and downregulation of YAP1 in medullary thyroid carcinoma

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12 December 2020

Hypermethylation of the Pendred syndrome gene SLC26A4 is an early event in thyroid tumorigenesis

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12 December 2020

[Relationship between methylation status of promoter and expression of XAF1 gene in papillary thyroid carcinoma].

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12 December 2020

MicroRNA-618 modulates cell growth via targeting PI3K/Akt pathway in human thyroid carcinomas

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12 December 2020

10.1007/S40291-017-0303-Y

Identifiers

DOI

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21 February 2018

Dimensions Publication ID

1092113508

0 references

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21 February 2018