(Q49700104)

21 February 2018

4 references

14 March 2019

24 March 2019

21 December 2019

25 January 2021

Endocrine Disrupting Chemicals Mediated through Binding Androgen Receptor Are Associated with Diabetes Mellitus. (English)

1 reference

21 February 2018

3 references

14 March 2019

24 March 2019

21 December 2019

intracellular receptor

1 reference

21 December 2019

1 reference

25 January 2021

6

Weida Tong

1 reference

21 February 2018

author name string

Sugunadevi Sakkiah

1

1 reference

21 February 2018

Tony Wang

2

1 reference

21 February 2018

Wen Zou

3

1 reference

21 February 2018

Yuping Wang

4

1 reference

21 February 2018

Bohu Pan

5

1 reference

21 February 2018

Huixiao Hong

7

1 reference

21 February 2018

language of work or name

1 reference

23 December 2017

5 references

21 February 2018

International Journal of Environmental Research and Public Health

14 March 2019

24 March 2019

21 December 2019

25 January 2021

5 references

21 February 2018

14 March 2019

24 March 2019

21 December 2019

25 January 2021

15

1 reference

21 February 2018

issue

1

1 reference

21 February 2018

Creative Commons Attribution

copyright license

4 references

14 March 2019

24 March 2019

21 December 2019

25 January 2021

0 references

on focus list of Wikimedia project

ScienceSource

0 references

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Development and Validation of Decision Forest Model for Estrogen Receptor Binding Prediction of Chemicals Using Large Data Sets

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Estrogenic activity data extraction and in silico prediction show the endocrine disruption potential of bisphenol A replacement compounds

22 May 2018

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Prevalence, Pathophysiology, and Management of Androgen Deficiency in Men with Metabolic Syndrome, Type 2 Diabetes Mellitus, or Both

22 May 2018

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Endocrine-disrupting chemicals, risk of type 2 diabetes, and diabetes-related metabolic traits: A systematic review and meta-analysis

22 May 2018

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The role of androgens in metabolism, obesity, and diabetes in males and females

22 May 2018

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22 May 2018

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Human sex hormone-binding globulin binding affinities of 125 structurally diverse chemicals and comparison with their binding to androgen receptor, estrogen receptor, and α-fetoprotein

22 May 2018

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Sexual dysfunction in women with diabetic kidney

22 May 2018

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Versatility or promiscuity: the estrogen receptors, control of ligand selectivity and an update on subtype selective ligands

22 May 2018

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Androgen receptor: structure, role in prostate cancer and drug discovery

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Pesticide use and incident diabetes among wives of farmers in the Agricultural Health Study

22 May 2018

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Homology modeling, molecular docking, and molecular dynamics simulations elucidated α-fetoprotein binding modes

22 May 2018

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Transmaternal bisphenol A exposure accelerates diabetes type 1 development in NOD mice

22 May 2018

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The sexually dimorphic role of adipose and adipocyte estrogen receptors in modulating adipose tissue expansion, inflammation, and fibrosis

22 May 2018

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22 May 2018

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Progesterone receptor isoforms PRA and PRB differentially contribute to breast cancer cell migration through interaction with focal adhesion kinase complexes

22 May 2018

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22 May 2018

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Development of silicon-containing bis-phenol derivatives as androgen receptor antagonists: selectivity switching by C/Si exchange

22 May 2018

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Mini-review: Foldosome regulation of androgen receptor action in prostate cancer

22 May 2018

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Rat α-Fetoprotein binding affinities of a large set of structurally diverse chemicals elucidated the relationships between structures and binding affinities

22 May 2018

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22 May 2018

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The emerging role of endocrine disruptors in pathogenesis of insulin resistance: a concept implicating nonalcoholic fatty liver disease

22 May 2018

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Targeting the binding function 3 (BF3) site of the human androgen receptor through virtual screening.

22 May 2018

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Urinary bisphenol A and type-2 diabetes in U.S. adults: data from NHANES 2003-2008

22 May 2018

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22 May 2018

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Inhibitors of androgen receptor activation function-2 (AF2) site identified through virtual screening

22 May 2018

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National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2·7 million participants

22 May 2018

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Polychlorinated biphenyls and organochlorine pesticides in plasma predict development of type 2 diabetes in the elderly: the prospective investigation of the vasculature in Uppsala Seniors (PIVUS) study

22 May 2018

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The EDKB: an established knowledge base for endocrine disrupting chemicals

22 May 2018

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Relationship between oxidative stress and inflammatory cytokines in diabetic nephropathy

22 May 2018

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Structural overview of the nuclear receptor superfamily: insights into physiology and therapeutics

22 May 2018

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Central administration of resveratrol improves diet-induced diabetes.

22 May 2018

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Anti-androgens and androgen-depleting therapies in prostate cancer: new agents for an established target

22 May 2018

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Effect of flavonoids on androgen and glucocorticoid receptors based on in vitro reporter gene assay

22 May 2018

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Resveratrol improves endothelial function: role of TNF{alpha} and vascular oxidative stress

22 May 2018

1 reference

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Kinetic and thermodynamic characterization of dihydrotestosterone-induced conformational perturbations in androgen receptor ligand-binding domain

22 May 2018

1 reference

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Adipose tissue dysfunction in obesity

22 May 2018

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17 beta-estradiol and tamoxifen upregulate estrogen receptor beta expression and control podocyte signaling pathways in a model of type 2 diabetes

22 May 2018

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Interference of pollutants with PPARs: endocrine disruption meets metabolism.

22 May 2018

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Testosterone in obesity, metabolic syndrome and type 2 diabetes

22 May 2018

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Resveratrol, a natural phytoalexin, normalizes hyperglycemia in streptozotocin-nicotinamide induced experimental diabetic rats

22 May 2018

1 reference

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The contribution of different androgen receptor domains to receptor dimerization and signaling

22 May 2018

1 reference

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Estrogen signaling multiple pathways to impact gene transcription

22 May 2018

1 reference

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Incident diabetes and pesticide exposure among licensed pesticide applicators: Agricultural Health Study, 1993-2003

22 May 2018

1 reference

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A surface on the androgen receptor that allosterically regulates coactivator binding

22 May 2018

1 reference

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Pesticide exposure and self-reported gestational diabetes mellitus in the Agricultural Health Study

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Testosterone replacement therapy improves insulin resistance, glycaemic control, visceral adiposity and hypercholesterolaemia in hypogonadal men with type 2 diabetes

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Comparison of crystal structures of human androgen receptor ligand-binding domain complexed with various agonists reveals molecular determinants responsible for binding affinity

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Sex differences of endogenous sex hormones and risk of type 2 diabetes: a systematic review and meta-analysis

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Estrogen receptors and human disease

22 May 2018

1 reference

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Molecular chaperones throughout the life cycle of the androgen receptor

22 May 2018

1 reference

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A cross-sectional study of the association between persistent organochlorine pollutants and diabetes

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Type 1 and type 2 diabetes: what do they have in common?

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Mechanisms of mineralocorticoid action

22 May 2018

1 reference

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The nuclear receptor superfamily: a personal retrospect on the first two decades

22 May 2018

1 reference

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Structural basis for antagonism and resistance of bicalutamide in prostate cancer

22 May 2018

1 reference

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Eplerenone: a selective aldosterone receptor antagonist for patients with heart failure

22 May 2018

1 reference

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Role of PPARalpha in mediating the effects of phthalates and metabolites in the liver.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Comparative molecular field analysis (CoMFA) model using a large diverse set of natural, synthetic and environmental chemicals for binding to the androgen receptor

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Activation of PPARalpha and PPARgamma by environmental phthalate monoesters

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Gestational diabetes and the incidence of type 2 diabetes: a systematic review

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Linking dioxins to diabetes: epidemiology and biologic plausibility

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Human health effects of dioxins: cancer, reproductive and endocrine system effects

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Increased adipose tissue in male and female estrogen receptor-alpha knockout mice

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Structural evidence for ligand specificity in the binding domain of the human androgen receptor. Implications for pathogenic gene mutations

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Mineralocorticoid receptor antagonists: The evolution of utility and pharmacology

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Androgen receptor antagonists (antiandrogens): structure-activity relationships

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Effects of the pesticide amitraz and its metabolite BTS 27271 on insulin and glucagon secretion from the perfused rat pancreas: involvement of alpha2D-adrenergic receptors

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Basic guide to the mechanisms of antiestrogen action

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Dioxin exposure and non-malignant health effects: a mortality study

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Glucocorticoid and mineralocorticoid receptors: biology and clinical relevance

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Regulation of the acute production of steroids in steroidogenic cells

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Cloning of Human Androgen Receptor Complementary DNA and Localization to the X Chromosome

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Structural organization of the human androgen receptor gene

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Glucocorticoid receptors and actions

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

TCDD (2,3,7,8-tetrachlorodibenzo-P-dioxin) causes reduction in glucose uptake through glucose transporters on the plasma membrane of the guinea pig adipocyte

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

An association between a Bc1I restriction fragment length polymorphism of the glucocorticoid receptor locus and hyperinsulinaemia in obese women

22 May 2018

1 reference

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Development of estrogen receptor beta binding prediction model using large sets of chemicals

22 May 2018

1 reference

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High T Gives β Cells a Boost

14 August 2018

1 reference

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Comparison of taurine and pantoyltaurine as antioxidants in vitro and in the central nervous system of diabetic rats.

14 August 2018

1 reference

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EADB: an estrogenic activity database for assessing potential endocrine activity.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Capsiate improves glucose metabolism by improving insulin sensitivity better than capsaicin in diabetic rats

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Effects of malathion subchronic exposure on rat skeletal muscle glucose metabolism

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Type 2 diabetes mellitus and testosterone: a meta-analysis study.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

An interpretation of positional displacement of the helix12 in nuclear receptors: preexistent swing-up motion triggered by ligand binding

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Dietary quercetin alleviates diabetic symptoms and reduces streptozotocin-induced disturbance of hepatic gene expression in mice.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Lower testosterone levels predict incident stroke and transient ischemic attack in older men.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Effect of eplerenone, enalapril and their combination treatment on diabetic nephropathy in type II diabetic rats

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Calcitrol (1alpha,25-dihydroxyvitamin D3) inhibits androgen glucuronidation in prostate cancer cells

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Low serum testosterone concentration in middle-aged men with type 2 diabetes

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Capsaicin-sensitive sensory fibers in the islets of Langerhans contribute to defective insulin secretion in Zucker diabetic rat, an animal model for some aspects of human type 2 diabetes.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Genistein and daidzein modulate hepatic glucose and lipid regulating enzyme activities in C57BL/KsJ-db/db mice.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Resveratrol, a polyphenolic phytoalexin, attenuates diabetic nephropathy in rats

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Association of hypogonadism and type II diabetes in men attending an outpatient erectile dysfunction clinic

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Hyperglycemia associated with increased hepatic glycogen phosphorylase and phosphoenolpyruvate carboxykinase in rats following subchronic exposure to malathion

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Study of 202 Natural, Synthetic, and Environmental Chemicals for Binding to the Androgen Receptor

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Effect of ovariectomy on adipose tissue of mice in the absence of estrogen receptor alpha (ERalpha): a potential role for estrogen receptor beta (ERbeta).

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Endogenous sex hormones and the development of type 2 diabetes in older men and women: the Rancho Bernardo study

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Beneficial effect of 1,25 dihydroxyvitamin D3 on cytokine-treated human pancreatic islets.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5800125

Metabolism of Testosterone and Action of Metabolites on Prostate Glands grown in Organ Culture

14 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.3390%2FIJERPH15010025

A canonical structure for the ligand-binding domain of nuclear receptors

21 January 2018

1 reference

12 December 2020

Activation Function 2 in the Human Androgen Receptor Ligand Binding Domain Mediates Interdomain Communication with the NH2-terminal Domain

1 reference

12 December 2020

The effect of atrazine on puberty in male wistar rats: an evaluation in the protocol for the assessment of pubertal development and thyroid function

1 reference

12 December 2020

The mechanisms by which both heterozygous peroxisome proliferator-activated receptor gamma (PPARgamma) deficiency and PPARgamma agonist improve insulin resistance

1 reference

12 December 2020

An in silico ensemble method for lead discovery: decision forest

1 reference

12 December 2020

Estrogen receptors: new players in diabetes mellitus

1 reference

12 December 2020

Androgens and diabetes in men: results from the Third National Health and Nutrition Examination Survey (NHANES III)

1 reference

12 December 2020

Association between androgen-deprivation therapy and incidence of diabetes among males with prostate cancer

1 reference

12 December 2020

Identifiers

DOI

10.3390/IJERPH15010025

1 reference

21 February 2018

PMCID

5800125

1 reference

21 February 2018

PubMed ID

29295509

1 reference

21 February 2018