(Q49790269)

22 February 2018

title

Translational control in the tumor microenvironment promotes lung metastasis: Phosphorylation of eIF4E in neutrophils (English)

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22 February 2018

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19

Nahum Sonenberg

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22 February 2018

Nathaniel Robichaud

1

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Santiago Ramon y Cajal

object named as

Santiago Ramón Y Cajal

14

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author name string

Brian E Hsu

2

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22 February 2018

Roman Istomine

3

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22 February 2018

Fernando Alvarez

4

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22 February 2018

Julianna Blagih

5

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22 February 2018

Eric H Ma

6

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22 February 2018

Sebastian V Morales

7

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22 February 2018

David L Dai

8

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22 February 2018

Glenn Li

9

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22 February 2018

Margarita Souleimanova

10

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22 February 2018

Qianyu Guo

11

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22 February 2018

Sonia V Del Rincon

12

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22 February 2018

Wilson H Miller

13

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22 February 2018

Morag Park

15

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22 February 2018

Russell G Jones

16

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22 February 2018

Ciriaco A Piccirillo

17

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22 February 2018

Peter M Siegel

18

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22 February 2018

language of work or name

English

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publication date

20 February 2018

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22 February 2018

Proceedings of the National Academy of Sciences of the United States of America

published in

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22 February 2018

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5877985/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Loss of Host Type-I IFN Signaling Accelerates Metastasis and Impairs NK-cell Antitumor Function in Multiple Models of Breast Cancer

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26 August 2018

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IL-17-producing γδ T cells and neutrophils conspire to promote breast cancer metastasis

26 August 2018

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Phosphorylation of eIF4E promotes EMT and metastasis via translational control of SNAIL and MMP-3.

26 August 2018

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Dramatic antitumor effects of the dual MET/RON small-molecule inhibitor LY2801653 in non-small cell lung cancer

26 August 2018

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26 August 2018

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26 August 2018

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26 August 2018

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LY2801653 is an orally bioavailable multi-kinase inhibitor with potent activity against MET, MST1R, and other oncoproteins, and displays anti-tumor activities in mouse xenograft models

26 August 2018

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Mnk1 and 2 are dispensable for T cell development and activation but important for the pathogenesis of experimental autoimmune encephalomyelitis

26 August 2018

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eIF4F suppression in breast cancer affects maintenance and progression

26 August 2018

1 reference

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26 August 2018

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26 August 2018

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Granulocyte-colony stimulating factor promotes lung metastasis through mobilization of Ly6G+Ly6C+ granulocytes

26 August 2018

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eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression

26 August 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5877985

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26 August 2018

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Dissecting eIF4E action in tumorigenesis

26 August 2018

1 reference

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Therapeutic suppression of translation initiation factor eIF4E expression reduces tumor growth without toxicity

26 August 2018

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Posttranscriptional regulation of TNFalpha expression via eukaryotic initiation factor 4E (eIF4E) phosphorylation in mouse macrophages

26 August 2018

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Phosphorylation of the eukaryotic translation initiation factor eIF4E contributes to its transformation and mRNA transport activities

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5877985

Influence of adjuvant hormone therapy and chemotherapy on the immune system analysed in the bone marrow of patients with breast cancer.

26 August 2018

1 reference

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Human eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4E

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5877985

MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substrates

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5877985

Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5877985

Quantitative selectivity of contact-mediated intercellular communication in a metastatic mouse mammary tumor line.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5877985

Characterization of metastatic heterogeneity among subpopulations of a single mouse mammary tumor: heterogeneity in phenotypic stability.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5877985

Selective events in the metastatic process defined by analysis of the sequential dissemination of subpopulations of a mouse mammary tumor

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5877985

Neutrophils, G-CSF and their contribution to breast cancer metastasis

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5877985

Inhibition of the immune response by rapamycin, a new antifungal antibiotic

2 November 2018

1 reference

12 December 2020

Serine 209, not serine 53, is the major site of phosphorylation in initiation factor eIF-4E in serum-treated Chinese hamster ovary cells

1 reference

12 December 2020

Phosphorylation of eukaryotic protein synthesis initiation factor 4E at Ser-209

1 reference

12 December 2020

Use of Ly6G-specific monoclonal antibody to deplete neutrophils in mice

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12 December 2020

Etiology and outcome of extreme leukocytosis in 758 nonhematologic cancer patients: a retrospective, single-institution study

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12 December 2020

Therapeutic inhibition of MAP kinase interacting kinase blocks eukaryotic initiation factor 4E phosphorylation and suppresses outgrowth of experimental lung metastases

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12 December 2020

Identifiers

DOI

10.1073/PNAS.1717439115

1 reference

22 February 2018

PMC publication ID

5877985

0 references

1 reference

22 February 2018