(Q49913713)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29453311%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

title

Visualization of ligand-induced transmembrane signaling in the full-length human insulin receptor (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29453311%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

main subject

transmembrane protein

0 references

1 reference

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29453311%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

Kelly H Kim

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29453311%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

Michal Grzybek

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29453311%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

Thomas Walz

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29453311%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

Ünal Coskun

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29453311%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

author name string

Thomas Walz

4

1 reference

http://europepmc.org/abstract/PMC/5940312

29 June 2018

language of work or name

English

0 references

publication date

16 February 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29453311%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

published in

Journal of Cell Biology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29453311%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

volume

217

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29453311%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29453311%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

page(s)

1643-1649

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29453311%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

17 March 2020

copyright license

start time

4 October 2019

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Higher-Resolution Structure of the Human Insulin Receptor Ectodomain: Multi-Modal Inclusion of the Insert Domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940312

Structural Dynamics of Insulin Receptor and Transmembrane Signaling

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940312

Ligand regulation of a constitutively dimeric EGF receptor

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940312

The insulin and IGF1 receptor kinase domains are functional dimers in the activated state.

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940312

Insulin/receptor binding: the last piece of the puzzle? What recent progress on the structure of the insulin/receptor complex tells us (or not) about negative cooperativity and activation

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940312

How IGF-1 activates its receptor

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940312

Insulin receptor activation with transmembrane domain ligands

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940312

Mechanisms of activation of receptor tyrosine kinases: monomers or dimers

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940312

Analysis of transmembrane domains and lipid modified peptides with matrix-assisted laser desorption ionization-time-of-flight mass spectrometry.

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940312

Solution structure of the transmembrane domain of the insulin receptor in detergent micelles

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940312

The insulin receptor changes conformation in unforeseen ways on ligand binding: sharpening the picture of insulin receptor activation

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940312

Nanodiscs as a new tool to examine lipid-protein interactions

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940312

Architecture and membrane interactions of the EGF receptor

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940312

How insulin engages its primary binding site on the insulin receptor

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940312

Iterative stable alignment and clustering of 2D transmission electron microscope images

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940312

Modulation of the interaction between neurotensin receptor NTS1 and Gq protein by lipid

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940312

Regulation of human EGF receptor by lipids

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940312

Lateral organization of complex lipid mixtures from multiscale modeling

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940312

Harmonic oscillator model of the insulin and IGF1 receptors' allosteric binding and activation

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940312

Quantitative analysis of phospholipids by thin-layer chromatography and phosphorus analysis of spots

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940312

Structure of the insulin receptor ectodomain reveals a folded-over conformation

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940312

SPARX, a new environment for Cryo-EM image processing

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940312

EMAN2: an extensible image processing suite for electron microscopy

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940312

Negative staining and image classification — powerful tools in modern electron microscopy

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940312

Epidermal growth factor receptor: association of extracellular domain negatively regulates intracellular kinase activation in the absence of ligand

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940312

Structural biology of insulin and IGF1 receptors: implications for drug design

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940312

Insulin signalling and the regulation of glucose and lipid metabolism

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940312

SPIDER and WEB: processing and visualization of images in 3D electron microscopy and related fields

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940312

The insulin receptor: structure, function, and signaling

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940312

Crystal structure of the tyrosine kinase domain of the human insulin receptor

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940312

Signal transduction by receptors with tyrosine kinase activity

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940312

A model for the quaternary structure of human placental insulin receptor deduced from electron microscopy

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940312

EGFR Ligands Differentially Stabilize Receptor Dimers to Specify Signaling Kinetics

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940312

Biochemical and cellular properties of insulin receptor signalling

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940312

Directed self-assembly of monodisperse phospholipid bilayer Nanodiscs with controlled size

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940312

Structural studies of the detergent-solubilized and vesicle-reconstituted insulin receptor

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940312

Biosynthesis and glycosylation of the insulin receptor. Evidence for a single polypeptide precursor of the two major subunits

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940312

Cooperativity in Cytochrome P450 3A4

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940312

Tryptic activation of the insulin receptor. Proteolytic truncation of the alpha-subunit releases the beta-subunit from inhibitory control

30 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29453311

12 December 2020

inferred from PubMed ID database lookup

Membrane topology of insulin receptors reconstituted into lipid vesicles

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29453311

12 December 2020

inferred from PubMed ID database lookup

Single-molecule imaging of human insulin receptor ectodomain and its Fab complexes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29453311

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1083/JCB.201711047

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29453311%20AND%20SRC:MED&resulttype=core&format=json

release_ardh5hxbkngotcr7j6vhhci6uy

17 March 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ardh5hxbkngotcr7j6vhhci6uy

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29453311%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

PubMed publication ID

29453311

1 reference