(Q50001638)

23 February 2018

title

Features and regulation of non-enzymatic post-translational modifications (English)

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23 February 2018

2

Dorothea Fiedler

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23 February 2018

author name string

Robert Harmel

series ordinal

1

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23 February 2018

publication date

1 February 2018

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23 February 2018

published in

Nature Chemical Biology

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23 February 2018

volume

14

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23 February 2018

issue

3

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23 February 2018

page(s)

244-252

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23 February 2018

Protein posttranslational modifications: the chemistry of proteome diversifications

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Identifying peroxidases and their oxidants in the early pathology of cystic fibrosis

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Glyoxal formation by Fenton-induced degradation of carbohydrates and related compounds

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7 January 2021

Mechanism of protein modification by glyoxal and glycolaldehyde, reactive intermediates of the Maillard reaction

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7 January 2021

Quantitative screening of advanced glycation endproducts in cellular and extracellular proteins by tandem mass spectrometry

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7 January 2021

Accumulation of Maillard reaction products in skin collagen in diabetes and aging

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S-(2-Succinyl)cysteine: a novel chemical modification of tissue proteins by a Krebs cycle intermediate

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Succination of proteins by fumarate: mechanism of inactivation of glyceraldehyde-3-phosphate dehydrogenase in diabetes

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Rare insights into cancer biology

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Aberrant succination of proteins in fumarate hydratase-deficient mice and HLRCC patients is a robust biomarker of mutation status

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Renal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: roles for fumarate in KEAP1 succination and Nrf2 signaling

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Loss of Keap1 function activates Nrf2 and provides advantages for lung cancer cell growth.

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Carbamoylation of amino acids and proteins in uremia

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Protein carbamylation links inflammation, smoking, uremia and atherogenesis.

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7 January 2021

Protein carbonylation, cellular dysfunction, and disease progression

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7 January 2021

Rapid and selective oxygen-regulated protein tyrosine denitration and nitration in mitochondria

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7 January 2021

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Characterization of a cellular denitrase activity that reverses nitration of cyclooxygenase

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Protein lysine acylation and cysteine succination by intermediates of energy metabolism

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7 January 2021

Identification of lysine succinylation as a new post-translational modification

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7 January 2021

Site-specific reactivity of nonenzymatic lysine acetylation

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7 January 2021

Discovering Targets of Non-enzymatic Acylation by Thioester Reactivity Profiling.

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7 January 2021

Nonenzymatic protein acylation as a carbon stress regulated by sirtuin deacylases

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7 January 2021

Lysine glutarylation is a protein posttranslational modification regulated by SIRT5

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7 January 2021

Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase

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7 January 2021

Widespread and enzyme-independent Nε-acetylation and Nε-succinylation of proteins in the chemical conditions of the mitochondrial matrix

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7 January 2021

A Class of Reactive Acyl-CoA Species Reveals the Non-enzymatic Origins of Protein Acylation

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7 January 2021

Is acetyl phosphate a global signal in Escherichia coli?

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7 January 2021

The intracellular concentration of acetyl phosphate in Escherichia coli is sufficient for direct phosphorylation of two-component response regulators

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7 January 2021

Protein polyphosphorylation of lysine residues by inorganic polyphosphate.

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7 January 2021

Inositol pyrophosphates inhibit Akt signaling, thereby regulating insulin sensitivity and weight gain

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7 January 2021

Inositol pyrophosphates regulate cell death and telomere length through phosphoinositide 3-kinase-related protein kinases

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7 January 2021

Inositol pyrophosphate mediated pyrophosphorylation of AP3B1 regulates HIV-1 Gag release

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7 January 2021

Inositol hexakisphosphate kinase 1 (IP6K1) activity is required for cytoplasmic dynein-driven transport

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7 January 2021

Unambiguous Identification of Serine and Threonine Pyrophosphorylation Using Neutral-Loss-Triggered Electron-Transfer/Higher-Energy Collision Dissociation.

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7 January 2021

Phosphorylation of proteins by inositol pyrophosphates

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7 January 2021

Protein pyrophosphorylation by inositol pyrophosphates is a posttranslational event

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7 January 2021

Elucidating diphosphoinositol polyphosphate function with nonhydrolyzable analogues

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7 January 2021

Cellular Cations Control Conformational Switching of Inositol Pyrophosphate Analogues.

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7 January 2021

Establishing the stability and reversibility of protein pyrophosphorylation with synthetic peptides

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7 January 2021

Evolution and functional cross-talk of protein post-translational modifications

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7 January 2021

Nitric oxide activates TRP channels by cysteine S-nitrosylation.

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7 January 2021

Active and dynamic mitochondrial S-depalmitoylation revealed by targeted fluorescent probes.

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.2575

7 January 2021

Binding and modification of proteins by methylglyoxal under physiological conditions. A kinetic and mechanistic study with N alpha-acetylarginine, N alpha-acetylcysteine, and N alpha-acetyllysine, and bovine serum albumin

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29443975

12 December 2020

inferred from PubMed ID database lookup

H2S signals through protein S-sulfhydration

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29443975

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NCHEMBIO.2575

1 reference

23 February 2018

1 reference

23 February 2018