(Q50056278)

English

Poldip2 is an oxygen-sensitive protein that controls PDH and αKGDH lipoylation and activation to support metabolic adaptation in hypoxia and cancer.

scientific article published on 6 February 2018

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scholarly article

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16 March 2020

Poldip2 is an oxygen-sensitive protein that controls PDH and αKGDH lipoylation and activation to support metabolic adaptation in hypoxia and cancer (English)

1 reference

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16 March 2020

Kathy K. Griendling

10

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16 March 2020

Samantha M Yeligar

9

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16 March 2020

Alejandra San Martín

12

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16 March 2020

Victor Darley-Usmar

11

object named as

Victor Darley-Usmar

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16 March 2020

author name string

Felipe Paredes

1

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16 March 2020

Kely Sheldon

2

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16 March 2020

Bernard Lassègue

3

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16 March 2020

Holly C Williams

4

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16 March 2020

Elizabeth A Faidley

5

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16 March 2020

Gloria A Benavides

6

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16 March 2020

Gloria Torres

7

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16 March 2020

Fernanda Sanhueza-Olivares

8

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16 March 2020

language of work or name

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publication date

6 February 2018

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16 March 2020

Proceedings of the National Academy of Sciences of the United States of America

1 reference

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16 March 2020

115

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16 March 2020

8

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16 March 2020

1789-1794

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16 March 2020

copyright license

Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International

6 February 2018

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

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TPpred2: improving the prediction of mitochondrial targeting peptide cleavage sites by exploiting sequence motifs.

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Poldip2 knockout results in perinatal lethality, reduced cellular growth and increased autophagy of mouse embryonic fibroblasts

1 reference

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Mutations in human lipoyltransferase gene LIPT1 cause a Leigh disease with secondary deficiency for pyruvate and alpha-ketoglutarate dehydrogenase

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Polymerase delta interacting protein 2 sustains vascular structure and function.

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Mitochondrial matrix proteases as novel therapeutic targets in malignancy.

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3 July 2018

Lipoic acid synthetase deficiency causes neonatal-onset epilepsy, defective mitochondrial energy metabolism, and glycine elevation

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The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored

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3 July 2018

Poldip2, a novel regulator of Nox4 and cytoskeletal integrity in vascular smooth muscle cells

1 reference

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Cell-permeating alpha-ketoglutarate derivatives alleviate pseudohypoxia in succinate dehydrogenase-deficient cells

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Identification of a novel protein, PDIP38, that interacts with the p50 subunit of DNA polymerase delta and proliferating cell nuclear antigen

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Human placental Na+-dependent multivitamin transporter. Cloning, functional expression, gene structure, and chromosomal localization

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3 July 2018

Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

1 reference

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Lipoic acid metabolism in Escherichia coli: the lplA and lipB genes define redundant pathways for ligation of lipoyl groups to apoprotein

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Mutations in the lipoyltransferase LIPT1 gene cause a fatal disease associated with a specific lipoylation defect of the 2-ketoacid dehydrogenase complexes.

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Lipoamide dehydrogenase deficiency with primary lactic acidosis: favorable response to treatment with oral lipoic acid

1 reference

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1 reference

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inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.1720693115

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29434038%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

1 reference

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16 March 2020

1 reference

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16 March 2020

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