(Q50063710)

24 February 2018

http://europepmc.org/abstract/MED/29432186

title

Adaptive antibody diversification through N-linked glycosylation of the immunoglobulin variable region. (English)

1 reference

24 February 2018

http://europepmc.org/abstract/MED/29432186

1 reference

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29432186%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Yoann Rombouts

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29432186%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Manfred Wuhrer

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29432186%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Gestur Vidarsson

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29432186%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

7

C Ellen van der Schoot

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29432186%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Fleur S van de Bovenkamp

1

object named as

Fleur S van de Bovenkamp

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29432186%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

2

Ninotska I L Derksen

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29432186%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Pleuni Ooijevaar-de Heer

3

object named as

Pleuni Ooijevaar-de Heer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29432186%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

4

Karin A van Schie

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29432186%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

5

Simone Kruithof

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29432186%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

11

Lise Hafkenscheid

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29432186%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

14

Rosina Plomp

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29432186%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

18

Theo Rispens

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29432186%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

author name string

Magdalena A Berkowska

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29432186%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Hanna IJspeert

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29432186%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Mirjam van der Burg

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29432186%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Ann Gils

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29432186%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

S Marieke van Ham

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29432186%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

language of work or name

English

0 references

publication date

5 February 2018

1 reference

24 February 2018

http://europepmc.org/abstract/MED/29432186

published in

Proceedings of the National Academy of Sciences of the United States of America

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29432186%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

volume

115

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29432186%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29432186%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

page(s)

1901-1906

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29432186%20AND%20SRC:MED&resulttype=core&format=json

Infusion reactions during infliximab treatment are not associated with IgE anti-infliximab antibodies.

2 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828577

The Immunobiology of Immunoglobulin G4.

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828577

Generation and characterization of a unique panel of anti-adalimumab specific antibodies and their application in therapeutic drug monitoring assays.

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828577

The Emerging Importance of IgG Fab Glycosylation in Immunity.

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828577

Sialylation of IgG Fc domain impairs complement-dependent cytotoxicity

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828577

DC-SIGN-expressing macrophages trigger activation of mannosylated IgM B-cell receptor in follicular lymphoma.

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828577

Lectin binding to surface Ig variable regions provides a universal persistent activating signal for follicular lymphoma cells.

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828577

Lectins from opportunistic bacteria interact with acquired variable-region glycans of surface immunoglobulin in follicular lymphoma

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828577

Extensive glycosylation of ACPA-IgG variable domains modulates binding to citrullinated antigens in rheumatoid arthritis.

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828577

Ig gene analysis reveals altered selective pressures on Ig-producing cells in parotid glands of primary Sjögren's syndrome patients

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828577

Functional analysis of the anti-adalimumab response using patient-derived monoclonal antibodies

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828577

Obinutuzumab: a new class of anti-CD20 monoclonal antibody.

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828577

Immunoglobulin G (IgG) Fab glycosylation analysis using a new mass spectrometric high-throughput profiling method reveals pregnancy-associated changes

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828577

Systematic characterization and comparative analysis of the rabbit immunoglobulin repertoire

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828577

Human immunoglobulin classes and subclasses show variability in VDJ gene mutation levels.

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828577

Redemption of autoantibodies on anergic B cells by variable-region glycosylation and mutation away from self-reactivity.

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828577

Hybridization-based antibody cDNA recovery for the production of recombinant antibodies identified by repertoire sequencing.

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828577

Nanomolar to sub-picomolar affinity measurements of antibody-antigen interactions and protein multimerizations: fluorescence-assisted high-performance liquid chromatography

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828577

Analysis and functional consequences of increased Fab-sialylation of intravenous immunoglobulin (IVIG) after lectin fractionation

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828577

Building high affinity human antibodies by altering the glycosylation on the light chain variable region in N-acetylglucosamine-supplemented hybridoma cultures

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828577

Enrichment of sialylated IgG by lectin fractionation does not enhance the efficacy of immunoglobulin G in a murine model of immune thrombocytopenia

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828577

IgE sequences in individuals living in an area of endemic parasitism show little mutational evidence of antigen selection.

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828577

Glycosylation of surface Ig creates a functional bridge between human follicular lymphoma and microenvironmental lectins

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828577

A close look at human IgG sialylation and subclass distribution after lectin fractionation

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828577

Terminal sugars of Fc glycans influence antibody effector functions of IgGs

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828577

Remarkable selective glycosylation of the immunoglobulin variable region in follicular lymphoma

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828577

Human follicular lymphoma cells contain oligomannose glycans in the antigen-binding site of the B-cell receptor.

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828577

Differential glycosylation of polyclonal IgG, IgG-Fc and IgG-Fab isolated from the sera of patients with ANCA-associated systemic vasculitis.

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828577

Acquisition of potential N-glycosylation sites in the immunoglobulin variable region by somatic mutation is a distinctive feature of follicular lymphoma.

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828577

Variable domain-linked oligosaccharides of a human monoclonal IgG: structure and influence on antigen binding

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828577

Site-specific glycosylation of human immunoglobulin G is altered in four rheumatoid arthritis patients

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828577

The amino acid at the X position of an Asn-X-Ser sequon is an important determinant of N-linked core-glycosylation efficiency.

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828577

The hydroxy amino acid in an Asn-X-Ser/Thr sequon can influence N-linked core glycosylation efficiency and the level of expression of a cell surface glycoprotein

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828577

Sub-class of IgG anti-bee venom antibody produced during bee venom immunotherapy and its relationship to long-term protection from bee stings and following termination of venom immunotherapy.

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828577

Glycosylation of a VH residue of a monoclonal antibody against alpha (1----6) dextran increases its affinity for antigen

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5828577

Genetically engineered deglycosylation of the variable domain increases the affinity of an anti-CD33 monoclonal antibody

8 September 2018

1 reference

12 December 2020

The variable domain glycosylation in a monoclonal antibody specific to GnRH modulates antigen binding

1 reference

12 December 2020

Effect of somatic hypermutation on potential N-glycosylation sites in human immunoglobulin heavy chain variable regions

1 reference

12 December 2020

Monitoring patients treated with anti-TNF-alpha biopharmaceuticals: assessing serum infliximab and anti-infliximab antibodies

1 reference

12 December 2020

IgG4 Production Against Adalimumab During Long Term Treatment of RA Patients

1 reference

12 December 2020

Quantitative glycan profiling of normal human plasma derived immunoglobulin and its fragments Fab and Fc

1 reference

12 December 2020

Antibodies to IgG4 hinge can be found in rheumatoid arthritis patients during all stages of disease and may exacerbate chronic antibody-mediated inflammation

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1711720115

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29432186%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29432186%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

1 reference