(Q50068874)

English

Simultaneous assessment of cytochrome P450 activity in cultured human hepatocytes for compound-mediated induction of CYP3A4, CYP2B6, and CYP1A2.

scientific article published on 24 November 2010

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scholarly article

1 reference

Europe PubMed Central

24 February 2018

http://europepmc.org/abstract/MED/21111054

Simultaneous assessment of cytochrome P450 activity in cultured human hepatocytes for compound-mediated induction of CYP3A4, CYP2B6, and CYP1A2. (English)

1 reference

Europe PubMed Central

24 February 2018

http://europepmc.org/abstract/MED/21111054

author name string

Susan P Rhodes

1

1 reference

Europe PubMed Central

24 February 2018

http://europepmc.org/abstract/MED/21111054

Jennifer N Otten

2

1 reference

Europe PubMed Central

24 February 2018

http://europepmc.org/abstract/MED/21111054

Gary P Hingorani

3

1 reference

Europe PubMed Central

24 February 2018

http://europepmc.org/abstract/MED/21111054

Dylan P Hartley

4

1 reference

Europe PubMed Central

24 February 2018

http://europepmc.org/abstract/MED/21111054

Ronald B Franklin

5

1 reference

Europe PubMed Central

24 February 2018

http://europepmc.org/abstract/MED/21111054

publication date

24 November 2010

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Europe PubMed Central

24 February 2018

http://europepmc.org/abstract/MED/21111054

Journal of Pharmacological and Toxicological Methods

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Europe PubMed Central

24 February 2018

http://europepmc.org/abstract/MED/21111054

63

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Europe PubMed Central

24 February 2018

http://europepmc.org/abstract/MED/21111054

3

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Europe PubMed Central

24 February 2018

http://europepmc.org/abstract/MED/21111054

223-226

1 reference

Europe PubMed Central

24 February 2018

http://europepmc.org/abstract/MED/21111054

Antimalarial artemisinin drugs induce cytochrome P450 and MDR1 expression by activation of xenosensors pregnane X receptor and constitutive androstane receptor.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.11.002

7 January 2021

Differential regulation of hepatic CYP2B6 and CYP3A4 genes by constitutive androstane receptor but not pregnane X receptor

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.11.002

7 January 2021

Regulation of CYP2B6 in primary human hepatocytes by prototypical inducers

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.11.002

7 January 2021

Relative activation of human pregnane X receptor versus constitutive androstane receptor defines distinct classes of CYP2B6 and CYP3A4 inducers

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.11.002

7 January 2021

Profiling induction of cytochrome p450 enzyme activity by statins using a new liquid chromatography-tandem mass spectrometry cocktail assay in human hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.11.002

7 January 2021

Primary hepatocytes: current understanding of the regulation of metabolic enzymes and transporter proteins, and pharmaceutical practice for the use of hepatocytes in metabolism, enzyme induction, transporter, clearance, and hepatotoxicity studies.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.11.002

7 January 2021

Assessment of cytochrome P450 induction in human hepatocytes using the cocktail strategy plus liquid chromatography tandem mass spectrometry.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.11.002

7 January 2021

Hepatic CYP2B6 expression: gender and ethnic differences and relationship to CYP2B6 genotype and CAR (constitutive androstane receptor) expression

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.11.002

7 January 2021

Identification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genes

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.11.002

7 January 2021

Expression and induction potential of cytochromes P450 in human cryopreserved hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.11.002

7 January 2021

Current industrial practices in assessing CYP450 enzyme induction: preclinical and clinical

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.11.002

7 January 2021

Identifiers

10.1016/J.VASCN.2010.11.002

1 reference

Europe PubMed Central

24 February 2018

http://europepmc.org/abstract/MED/21111054

1 reference

Europe PubMed Central

24 February 2018

http://europepmc.org/abstract/MED/21111054

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