(Q50088359)

24 February 2018

title

The Immunosuppressant Brasilicardin: Determination of the Biosynthetic Gene Cluster in the Heterologous Host Amycolatopsis japonicum. (English)

1 reference

24 February 2018

1 reference

Brasilicardin C aglycone

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inferred from

reverse claim

Brasilicardin D aglycone

1 reference

inferred from

reverse claim

Amycolatopsis japonica

1 reference

Andreas Kulik

4

0 references

author name string

Paul N Schwarz

1

1 reference

24 February 2018

Anina Buchmann

2

1 reference

24 February 2018

Luisa Roller

3

1 reference

24 February 2018

Harald Gross

5

1 reference

24 February 2018

Wolfgang Wohlleben

6

1 reference

24 February 2018

Evi Stegmann

7

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24 February 2018

publication date

16 October 2017

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24 February 2018

published in

Biotechnology Journal

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24 February 2018

volume

13

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24 February 2018

issue

2

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24 February 2018

High-Quality Draft Genome Sequence of the Actinobacterium Nocardia terpenica IFM 0406, Producer of the Immunosuppressant Brasilicardins, Using Illumina and PacBio Technologies

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Characterization of a human regulatory subunit of protein phosphatase 3 gene (PPP3RL) expressed specifically in testis

21 January 2018

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Immunopharmacology of rapamycin

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Cardiovascular toxicities of immunosuppressive agents

21 January 2018

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Effects of the immunosuppressive drugs CsA and FK506 on intracellular signalling and gene regulation

21 January 2018

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Immunosuppressive drugs for kidney transplantation.

21 January 2018

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SAR studies of brasilicardin A for immunosuppressive and cytotoxic activities.

21 January 2018

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The mechanism of action of cyclosporin A and FK506.

21 January 2018

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Brasilicardin A, a natural immunosuppressant, targets amino Acid transport system L.

21 January 2018

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Se-phenyl prop-2-eneselenoate: an ethylene equivalent for Diels-Alder reactions

21 January 2018

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Synthesis and Bioactivity of a Brasilicardin A Analogue Featuring a Simplified Core.

21 January 2018

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Recent advances in the heterologous expression of microbial natural product biosynthetic pathways

21 January 2018

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Rapid construction of a Bacterial Artificial Chromosomal (BAC) expression vector using designer DNA fragments

21 January 2018

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Artificial chromosomes to explore and to exploit biosynthetic capabilities of actinomycetes

21 January 2018

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Development of a genetic system for combinatorial biosynthesis of lipopeptides in Streptomyces fradiae and heterologous expression of the A54145 biosynthesis gene cluster

21 January 2018

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Engineered production of iso-migrastatin in heterologous Streptomyces hosts

21 January 2018

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Rapid cloning and heterologous expression of the meridamycin biosynthetic gene cluster using a versatile Escherichia coli-streptomyces artificial chromosome vector, pSBAC.

21 January 2018

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Antibiotic drug discovery.

21 January 2018

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Heterologous expression of natural product biosynthetic gene clusters in Streptomyces coelicolor: from genome mining to manipulation of biosynthetic pathways

21 January 2018

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Microbisporicin gene cluster reveals unusual features of lantibiotic biosynthesis in actinomycetes

21 January 2018

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Isolation, characterization, and heterologous expression of the biosynthesis gene cluster for the antitumor anthracycline steffimycin

21 January 2018

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Development of three different gene cloning systems for genetic investigation of the new species Amycolatopsis japonicum MG417-CF17, the ethylenediaminedisuccinic acid producer

21 January 2018

1 reference

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Overproduction of Ristomycin A by activation of a silent gene cluster in Amycolatopsis japonicum MG417-CF17.

21 January 2018

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Elucidation of the zinc-dependent regulation in Amycolatopsis japonicum enabled the identification of the ethylenediamine-disuccinate ([S,S]-EDDS) genes

21 January 2018

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On a Test of Whether one of Two Random Variables is Stochastically Larger than the Other

21 January 2018

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Complete genome sequence of the actinobacterium Amycolatopsis japonica MG417-CF17(T) (=DSM 44213T) producing (S,S)-N,N'-ethylenediaminedisuccinic acid

21 January 2018

1 reference

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Functional analysis of the N-acetylglucosamine metabolic genes of Streptomyces coelicolor and role in control of development and antibiotic production

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201700527

Engineering of N-acetylglucosamine metabolism for improved antibiotic production in Streptomyces coelicolor A3(2) and an unsuspected role of NagA in glucosamine metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201700527

Control of chitin and N-acetylglucosamine utilization in Saccharopolyspora erythraea.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201700527

Cloning of the gene cluster responsible for the biosynthesis of brasilicardin A, a unique diterpenoid

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201700527

Biosynthesis of the immunosuppressants FK506, FK520, and rapamycin involves a previously undescribed family of enzymes acting on chorismate

21 January 2018

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Tuning the moenomycin pharmacophore to enable discovery of bacterial cell wall synthesis inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201700527

Biosynthesis of the terpene phenalinolactone in Streptomyces sp. Tü6071: analysis of the gene cluster and generation of derivatives

21 January 2018

1 reference

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Glycopeptide biosynthesis in the context of basic cellular functions

21 January 2018

1 reference

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The biosynthesis of vancomycin-type glycopeptide antibiotics--a model for oxidative side-chain cross-linking by oxygenases coupled to the action of peptide synthetases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201700527

Genetic analysis of the balhimycin (vancomycin-type) oxygenase genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201700527

The biosynthesis of teicoplanin-type glycopeptide antibiotics: assignment of p450 mono-oxygenases to side chain cyclizations of glycopeptide a47934.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201700527

Heterologous expression of the thiopeptide antibiotic GE2270 from Planobispora rosea ATCC 53733 in Streptomyces coelicolor requires deletion of ribosomal genes from the expression construct.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201700527

Analysis of Streptomyces avermitilis genes required for avermectin biosynthesis utilizing a novel integration vector

21 January 2018

1 reference

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One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201700527

The role of the novel Fem protein VanK in vancomycin resistance in Streptomyces coelicolor

21 January 2018

1 reference

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Production by actinomycetes of (S,S)-N,N'-ethylenediaminedisuccinic acid, an inhibitor of phospholipase C

21 January 2018

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9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/BIOT.201700527

High efficiency intergeneric conjugal transfer of plasmid DNA from Escherichia coli to methyl DNA-restricting streptomycetes

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/BIOT.201700527

Novel Synthetic Approach to the 8,10-Dimethyl anti-syn-anti-Perhydrophenanthrene Skeleton

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/BIOT.201700527

A restriction enzyme map of R-plasmid RP1

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/BIOT.201700527

Brasilicardins B–D, new tricyclic terpernoids from actinomycete Nocardia brasiliensis

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/BIOT.201700527

Evidence that the extracytoplasmic function sigma factor sigmaE is required for normal cell wall structure in Streptomyces coelicolor A3(2).

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/BIOT.201700527

Brasilicardin A, a new terpenoid antibiotic from pathogenic Nocardia brasiliensis: fermentation, isolation and biological activity

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/BIOT.201700527

Teichomycins, new antibiotics from Actinoplanes teichomyceticus Nov. Sp. I. Description of the producer strain, fermentation studies and biological properties

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/BIOT.201700527

Biosynthetic gene cluster of the glycopeptide antibiotic teicoplanin: characterization of two glycosyltransferases and the key acyltransferase

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/BIOT.201700527

Brasilicardin A. A Novel Tricyclic Metabolite with Potent Immunosuppressive Activity from Actinomycete Nocardiabrasiliensis

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/BIOT.201700527

Identifiers

DOI

10.1002/BIOT.201700527

1 reference

24 February 2018

release_mxpijbjm3vabhgz4qzodhwybwe

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/mxpijbjm3vabhgz4qzodhwybwe

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

24 February 2018