(Q50122103)

25 February 2018

title

Modeling the mouse lymphoma forward mutational assay: the Gene-Tox program database. (English)

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25 February 2018

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Grant SG

1

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25 February 2018

Zhang YP

series ordinal

2

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25 February 2018

Klopman G

series ordinal

3

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25 February 2018

Rosenkranz HS

series ordinal

4

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25 February 2018

language of work or name

English

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publication date

1 February 2000

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25 February 2018

published in

Mutation Research

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25 February 2018

volume

465

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25 February 2018

issue

1-2

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25 February 2018

page(s)

201-229

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25 February 2018

Induction of forward mutations at the thymidine kinase locus of mouse lymphoma cells: evidence for electrophilic and non-electrophilic mechanisms.

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7 January 2021

The L5178Y/tk+/- mouse lymphoma specific gene and chromosomal mutation assay a phase III report of the U.S. Environmental Protection Agency Gene-Tox Program

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7 January 2021

Dichotomous relationship between DNA reactivity and the induction of sister chromatid exchanges in vivo and in vitro.

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7 January 2021

Identification of 'genotoxic' and 'non-genotoxic' alerts for cancer in mice: the carcinogenic potency database.

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7 January 2021

Prediction of the carcinogenicity of a second group of organic chemicals undergoing carcinogenicity testing

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7 January 2021

Estimation of the optimal data base size for structure-activity analyses: the Salmonella mutagenicity data base

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7 January 2021

An approach for evaluating and increasing the informational content of mutagenicity and clastogenicity data bases

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7 January 2021

Structural basis of the in vivo induction of micronuclei.

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7 January 2021

Definitive relationships among chemical structure, carcinogenicity and mutagenicity for 301 chemicals tested by the U.S. NTP

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7 January 2021

Formation of direct-acting genotoxic substances in nitrosated smoked fish and meat products: identification of simple phenolic precursors and phenyldiazonium ions as reactive products

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7 January 2021

Structural basis of the genotoxicity of nitrosatable phenols and derivatives present in smoked food products

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7 January 2021

Identification of a 2-D geometric descriptor associated with non-genotoxic carcinogens and some estrogens and antiestrogens.

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7 January 2021

A dichotomy in the lipophilicity of natural estrogens, xenoestrogens, and phytoestrogens

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7 January 2021

Structural analysis of a group of phytoestrogens for the presence of a 2-D geometric descriptor associated with non-genotoxic carcinogens and some estrogens

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7 January 2021

Structural evidence for a dichotomy in rodent carcinogenesis: involvement of genetic and cellular toxicity

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7 January 2021

Evidence that cell toxicity may contribute to the genotoxic response

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7 January 2021

Structure-activity and mechanistic relationships: the effect of chemical overlap on structural overlap in data bases of varying size and composition

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7 January 2021

Validation and characterization of the L5178Y/TK+/- mouse lymphoma mutagen assay system

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7 January 2021

Genotoxicity of acrylic acid, methyl acrylate, ethyl acrylate, methyl methacrylate, and ethyl methacrylate in L5178Y mouse lymphoma cells

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7 January 2021

Analysis of the genotoxicity of nine acrylate/methacrylate compounds in L5178Y mouse lymphoma cells.

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7 January 2021

Expression of recessive alleles by chromosomal mechanisms in retinoblastoma

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7 January 2021

Segregation of recessive phenotypes in somatic cell hybrids: role of mitotic recombination, gene inactivation, and chromosome nondisjunction

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7 January 2021

Expression of recessive Aprt- mutations in mouse CAK cells resulting from chromosome loss and duplication

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https://api.crossref.org/works/10.1016%2FS1383-5718%2899%2900186-2

7 January 2021

The detection of chemically induced chromosomal malsegregation in Saccharomyces cerevisiae D61.M: A literature survey (1984–1990)

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2899%2900186-2

7 January 2021

International Commission for Protection against Environmental Mutagens and Carcinogens. Recombination and gene conversion

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https://api.crossref.org/works/10.1016%2FS1383-5718%2899%2900186-2

7 January 2021

Tests for recombinagens in fungi

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7 January 2021

Genetic demonstration of mitotic recombination in cultured Chinese hamster cell hybrids.

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7 January 2021

Mutations in human lymphocytes commonly involve gene duplication and resemble those seen in cancer cels

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7 January 2021

Gene conversion in mitotically dividing cells: a view from Drosophila

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7 January 2021

Reversible inactivation of autosomal alleles in Chinese hamster cells

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7 January 2021

Induction of thymidine kinase in enzyme-deficient chinese hamster cells

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7 January 2021

Prediction of chemical carcinogenicity in rodents from in vitro genetic toxicity assays.

1 reference

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7 January 2021

Evaluation of four in vitro genetic toxicity tests for predicting rodent carcinogenicity: confirmation of earlier results with 41 additional chemicals

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2899%2900186-2

7 January 2021

The structural basis of the carcinogenic and mutagenic potentials of phytoalexins.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2899%2900186-2

7 January 2021

Molecular analyses of in vivo hprt mutations in human T-lymphocytes. I. Studies of low frequency 'spontaneous' mutants by Southern blots

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2899%2900186-2

7 January 2021

Sensitivity of somatic mutations in human umbilical cord blood to maternal environments

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2899%2900186-2

7 January 2021

Molecular dissection of mutations at the heterozygous thymidine kinase locus in mouse lymphoma cells

1 reference

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7 January 2021

Cytogenetic distinction between the TK+ and TK- chromosomes in the L5178Y TK+/- 3.7.2C mouse-lymphoma cell line

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7 January 2021

In vitro mammalian mutagenesis as a model for genetic lesions in human cancer

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7 January 2021

Multiplex DNA deletion detection and exon sequencing of the hypoxanthine phosphoribosyltransferase gene in Lesch-Nyhan families

1 reference

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7 January 2021

Multiplex PCR analysis of in vivo-arising deletion mutations in the hprt gene of human T-lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2899%2900186-2

7 January 2021

Databases and software for the analysis of mutations in the human p53 gene, human hprt gene and both the lacI and lacZ gene in transgenic rodents

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2899%2900186-2

7 January 2021

Loss of heterozygosity and mitotic linkage maps in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2899%2900186-2

7 January 2021

The mouse lymphoma L5178Y Tk+/- cell line is heterozygous for a codon 170 mutation in the p53 tumor suppressor gene

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2899%2900186-2

7 January 2021

10.1016/S1383-5718(99)00186-2

Identifiers

DOI

1 reference

25 February 2018

PubMed ID

10708987

1 reference

25 February 2018