(Q50132797)

25 February 2018

title

Genetic toxicity studies of 1,2,3,4-tetrahydro-9-acridinamine (tacrine). (English)

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25 February 2018

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Zeiger E

1

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25 February 2018

Erexson G

series ordinal

2

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25 February 2018

Mortelmans K

series ordinal

3

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25 February 2018

Thilagar A

series ordinal

4

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25 February 2018

language of work or name

English

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publication date

1 October 1997

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25 February 2018

published in

Mutation Research

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25 February 2018

volume

393

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25 February 2018

issue

3

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25 February 2018

page(s)

189-197

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25 February 2018

Oral tetrahydroaminoacridine in long-term treatment of senile dementia, Alzheimer type.

cites work

1 reference

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7 January 2021

Hepatotoxic effects of tacrine administration in patients with Alzheimer's disease

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7 January 2021

Frameshift mutagenesis by acridines and other reversibly-binding DNA ligands

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7 January 2021

The genetic toxicology of acridines

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7 January 2021

Genotoxicity of tacrine in primary hepatocytes isolated from B6C3F1 mice and aged ad libitum and calorie restricted Fischer 344 rats

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7 January 2021

Salmonella mutagenicity tests: IV. Results from the testing of 300 chemicals.

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7 January 2021

Development of a standard protocol for in vitro cytogenetic testing with Chinese hamster ovary cells: comparison of results for 22 compounds in two laboratories

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7 January 2021

Chromosome aberrations and sister chromatid exchanges in Chinese hamster ovary cells: evaluations of 108 chemicals

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7 January 2021

Statistical analyses for in vitro cytogenetic assays using Chinese hamster ovary cells.

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7 January 2021

Effect of treatment protocol and sample time on the frequencies of micronucleated polychromatic erythrocytes in mouse bone marrow and peripheral blood

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7 January 2021

Three consistent patterns of response to substituted acridines in a variety of bacterial tester strains used for mutagenicity testing.

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7 January 2021

Quantitative whole-body autoradiographic determination of tacrine tissue distribution in rats following intravenous or oral dose

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7 January 2021

Species variation in the bioactivation of tacrine by hepatic microsomes

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7 January 2021

An investigation into the formation of stable, protein-reactive and cytotoxic metabolites from tacrine in vitro. Studies with human and rat liver microsomes

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7 January 2021

Cytotoxicity of tacrine and velnacrine metabolites in cultured rat, dog and human hepatocytes

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7 January 2021

Identification of 9-hydroxylamine-1,2,3,4-tetrahydroacridine as a hepatic microsomal metabolite of tacrine by high-performance liquid chromatography and electrochemistry

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2897%2900096-X

7 January 2021

Comparison of tacrine-induced cytotoxicity in primary cultures of rat, mouse, monkey, dog, rabbit, and human hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2897%2900096-X

7 January 2021

Cytotoxicity study of tacrine, structurally and pharmacologically related compounds using rat hepatocytes

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https://api.crossref.org/works/10.1016%2FS1383-5718%2897%2900096-X

7 January 2021

Topoisomerase II enzymes and mutagenicity

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7 January 2021

10.1016/S1383-5718(97)00096-X

Identifiers

DOI

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25 February 2018

1 reference

25 February 2018