(Q50142696)

English

A physiological model for ligand-induced accumulation of alpha 2u globulin in male rat kidney: roles of protein synthesis and lysosomal degradation in the renal dosimetry of 2,4,4-trimethyl-2-pentanol.

scientific article published in August 1999

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

25 February 2018

http://europepmc.org/abstract/MED/10514002

A physiological model for ligand-induced accumulation of alpha 2u globulin in male rat kidney: roles of protein synthesis and lysosomal degradation in the renal dosimetry of 2,4,4-trimethyl-2-pentanol. (English)

1 reference

Europe PubMed Central

PubMed publication ID

25 February 2018

http://europepmc.org/abstract/MED/10514002

2

object named as

Melnick RL

1 reference

Europe PubMed Central

PubMed publication ID

25 February 2018

http://europepmc.org/abstract/MED/10514002

author name string

Kohn MC

1

1 reference

Europe PubMed Central

PubMed publication ID

25 February 2018

http://europepmc.org/abstract/MED/10514002

language of work or name

0 references

publication date

1 August 1999

1 reference

Europe PubMed Central

PubMed publication ID

25 February 2018

http://europepmc.org/abstract/MED/10514002

number of pages

17

1 reference

based on heuristic

inferred from page(s)

1 reference

Europe PubMed Central

PubMed publication ID

25 February 2018

http://europepmc.org/abstract/MED/10514002

136

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Europe PubMed Central

PubMed publication ID

25 February 2018

http://europepmc.org/abstract/MED/10514002

2-3

1 reference

Europe PubMed Central

PubMed publication ID

25 February 2018

http://europepmc.org/abstract/MED/10514002

89-105

1 reference

Europe PubMed Central

PubMed publication ID

25 February 2018

http://europepmc.org/abstract/MED/10514002

Cellular and molecular mechanisms of chemically induced renal carcinogenesis

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Biochemical Mechanisms and Pathobiology of α2u-Globulin Nephropathy

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Characteristics of chemical binding to α2u-globulin, in vitro—Evaluating structure-activity relationships

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A comparison of European High Test gasoline and PS-6 unleaded gasoline in their abilities to induce alpha 2u-globulin nephropathy and renal cell proliferation

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Development of a mechanism-based dosimetry model for 2,4,4-trimethyl-2-pentanol-induced alpha 2u-globulin nephropathy in male Fischer 344 rats

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2,2,4-Trimethylpentane-induced nephrotoxicity. I. Metabolic disposition of TMP in male and female Fischer 344 rats

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Physiological parameters in laboratory animals and humans

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Partition coefficients of low-molecular-weight volatile chemicals in various liquids and tissues

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Effect of thyroid hormones on the level of the hepatic mRNA for α2u globulin

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Alpha 2u-globulin is the only member of the lipocalin protein superfamily that binds to hyaline droplet inducing agents

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Lysosomal degradation of alpha 2u-globulin and alpha 2u-globulin-xenobiotic conjugates

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Risk of cancer and exposure to gasoline vapors.

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Isolation of kidney lysosomes

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An alternative hypothesis on the role of chemically induced protein droplet (α2u-globulin) nephropathy in renal carcinogenesis

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Hydrocarbon-induced hyaline droplet nephropathy in male rats during senescence.

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Age-Dependent Changes in the Excretion of Urinary Proteins by the Rat

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Urinary excretion of alpha 2 mu-globulin and albumin by adult male rats following treatment with nephrotoxic agents

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Dietary control of the renal reabsorption and excretion of α2u-globulin

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Effect of low-molecular-weight dextran on proteolytic and nonproteolytic lysosomal enzymes in isolated segments of rat proximal tubule

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Accumulation of alpha 2u-globulin in the renal proximal tubules of male rats exposed to unleaded gasoline

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Renal cell cancer and occupational exposure to chemical agents.

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Methyl tert-butyl ether causes alpha2u-globulin nephropathy and enhanced renal cell proliferation in male Fischer-344 rats.

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Alpha 2u-globulins in the urine of male rats: a reliable indicator for alpha 2u-globulin accumulation in the kidney

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Alpha 2U-globulin: measurement in rat kidney following administration of 2,2,4-trimethylpentane

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Identifiers

10.1016/S0300-483X(99)00063-3

1 reference

Europe PubMed Central

PubMed publication ID

25 February 2018

http://europepmc.org/abstract/MED/10514002

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

25 February 2018

http://europepmc.org/abstract/MED/10514002

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