(Q50259852)

English

CHUK:IKBKB:IKBKG [cytosol]

An instance of macromolecular complex in Homo sapiens with Reactome ID (R-HSA-168113)

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2 references

8 July 2022

8 July 2022

https://www.ebi.ac.uk/complexportal/complex/CPX-3269

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CHUK, IKBKB and IKBKG form IKK complex

1 reference

8 July 2022

CHUK:IKBKB:IKBKG:K63pUb-RIP1:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane]

1 reference

8 July 2022

IKKB phosphorylates SNAP23

1 reference

8 July 2022

Phosphorylation of IKK-beta by TAK1

1 reference

8 July 2022

Poly-K6-Ub-hp-IRAK1:CHUK:IKBKB:IKBKG [cytosol]

1 reference

8 July 2022

NEMO binds polyubiquitinated IRAK1

1 reference

8 July 2022

NEMO subunit of IKK complex binds to activated IRAK1

1 reference

8 July 2022

TRAF6:K63-linked polyUb p-IRAK1:IKK complex [cytosol]

1 reference

8 July 2022

Activation of IKK by MEKK1

1 reference

8 July 2022

Activated TAK1 mediates phosphorylation of the IKK Complex

1 reference

8 July 2022

K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta

1 reference

8 July 2022

CARMA1:BCL10:MALT1 complex recruits TAK1 and IKK

1 reference

8 July 2022

GNB2L1 binds IKKA:IKKB:NEMO

1 reference

8 July 2022

dsRNA:RIG-I/MDA5:TRAF2/TRAF6:IPS-1:RIP-1/FADD:Casp-8/10 prodomain:IKK complex [mitochondrial outer membrane]

1 reference

8 July 2022

TRAF6:K63-linked polyUb p-IRAK1:IKK complex [endosome membrane]

1 reference

8 July 2022

Recruitment of IKK complex

1 reference

8 July 2022

TNFalpha:TNF-R1:TRADD:K63polyUb-RIP1:BIRC2/3:IKKA:IKKB:NEMO [plasma membrane]

1 reference

8 July 2022

Activation of IKK complex

1 reference

8 July 2022

TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2,3:LUBAC recruits IKKA:IKBKB:IKBKG

1 reference

8 July 2022

p-CARMA1:MALT1:p-BCL10:TAK1:IKK [plasma membrane]

1 reference

8 July 2022

NEMO subunit of IKK complex binds to activated IRAK1 upon stimulation of TLR7/8 or 9.

1 reference

8 July 2022

IKBKG subunit of IKK complex binds polyubiquinated RIP1

1 reference

8 July 2022

RIP1 facilitates IKK complex phosphorylation

1 reference

8 July 2022

IKKA:IKKB:NEMO:GNB2L1 [cytosol]

1 reference

8 July 2022

IKBKG subunit of IKK complex binds K63pUb- RIP1 within the TLR3 complex

1 reference

8 July 2022

viral dsRNA:TLR3:TICAM1:K63pUb-RIP1:CHUK:IKBKB:IKBKG [endosome membrane]

1 reference

8 July 2022

SARS-CoV-2 N binds IKBKB

1 reference

8 July 2022

CHUK:IKBKB:IKBKG:K63polyUb-NLRX1 [cytosol]

1 reference

8 July 2022

9b:IKK complex [mitochondrial outer membrane]

1 reference

8 July 2022

NLRX1 binds CHUK:IKBKB:IKBKG

1 reference

8 July 2022

N:CHUK:IKBKB:IKBKG [cytosol]

1 reference

8 July 2022

CHUK:IKBKB:IKBKG:USP18 [cytosol]

1 reference

8 July 2022

SARS-CoV-2 9b binds IKBKG

1 reference

8 July 2022

USP18 binds IKBKG within IKK complex

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-168113

1 reference

8 July 2022

Inhibitor of nuclear factor kappa B kinase subunit beta

quantity

1

1 reference

8 July 2022

Component of inhibitor of nuclear factor kappa B kinase complex

quantity

1

1 reference

8 July 2022

Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma

quantity

1

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

(Q50259852)

CHUK:IKBKB:IKBKG [cytosol]

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