(Q50273159)

28 February 2018

title

Adenosinergic Immunosuppression by Human Mesenchymal Stromal Cells Requires Co-Operation with T cells. (English)

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28 February 2018

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1

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Maarit Takatalo

5

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28 February 2018

Petri Lehenkari

10

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28 February 2018

Anita Laitinen

Anita Laitinen

2

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Sami Valkonen

Sami Valkonen

4

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Pia Siljander

Pia Siljander

9

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Saara Laitinen

12

Saara Laitinen

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28 February 2018

author name string

Jarkko Räbinä

3

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28 February 2018

Antti Larjo

6

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28 February 2018

Johanna Veijola

7

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28 February 2018

Milla Lampinen

8

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28 February 2018

Kaija Alfthan

11

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28 February 2018

publication date

5 January 2016

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28 February 2018

published in

Stem Cells

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28 February 2018

volume

34

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28 February 2018

issue

3

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28 February 2018

page(s)

781-790

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28 February 2018

Mesenchymal stem/stromal cells (MSCs): role as guardians of inflammation

cites work

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Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli

21 January 2018

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Suppression of allogeneic T-cell proliferation by human marrow stromal cells: implications in transplantation

21 January 2018

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Human mesenchymal stem cells modulate allogeneic immune cell responses

21 January 2018

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Mesenchymal stem cells inhibit lymphocyte proliferation by mitogens and alloantigens by different mechanisms

21 January 2018

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Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2,3-dioxygenase-mediated tryptophan degradation

21 January 2018

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Physiological control of immune response and inflammatory tissue damage by hypoxia-inducible factors and adenosine A2A receptors.

21 January 2018

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Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression.

21 January 2018

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Generation and accumulation of immunosuppressive adenosine by human CD4+CD25highFOXP3+ regulatory T cells

21 January 2018

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High expression of the ectonucleotidase CD39 on T cells from the inflamed site identifies two distinct populations, one regulatory and one memory T cell population

21 January 2018

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Adenosine production by human B cells and B cell-mediated suppression of activated T cells

21 January 2018

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CD73: a potent suppressor of antitumor immune responses

21 January 2018

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Mesenchymal stromal cells up-regulate CD39 and increase adenosine production to suppress activated T-lymphocytes

21 January 2018

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CD39-mediated effect of human bone marrow-derived mesenchymal stem cells on the human Th17 cell function

21 January 2018

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Bone marrow-derived mesenchymal stromal cells harness purinergenic signaling to tolerize human Th1 cells in vivo

21 January 2018

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Membrane-derived microvesicles: important and underappreciated mediators of cell-to-cell communication

21 January 2018

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Microvesicles derived from mesenchymal stem cells: potent organelles for induction of tolerogenic signaling.

21 January 2018

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Mesenchymal stem cells secrete immunologically active exosomes

21 January 2018

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The isolation and culture of human cord blood-derived mesenchymal stem cells under low oxygen conditions.

21 January 2018

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Osteoblast recruitment from stem cells does not decrease by age at late adulthood

21 January 2018

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T regulatory and primed uncommitted CD4 T cells express CD73, which suppresses effector CD4 T cells by converting 5'-adenosine monophosphate to adenosine

21 January 2018

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Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression

21 January 2018

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CD39 is highly involved in mediating the suppression activity of tumor-infiltrating CD8+ T regulatory lymphocytes

21 January 2018

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CD39 is involved in mediating suppression by Mycobacterium bovis BCG-activated human CD8(+) CD39(+) regulatory T cells.

21 January 2018

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Human CD4+ CD39+ regulatory T cells produce adenosine upon co-expression of surface CD73 or contact with CD73+ exosomes or CD73+ cells

21 January 2018

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CD39 and control of cellular immune responses

21 January 2018

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Increased expression of the FoxP3 functional marker of regulatory T cells following B cell depletion with rituximab in patients with lupus nephritis.

21 January 2018

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CD39/NTPDase-1 activity and expression in normal leukocytes

21 January 2018

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Cancer exosomes express CD39 and CD73, which suppress T cells through adenosine production.

21 January 2018

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CD73 expression on extracellular vesicles derived from CD4+ CD25+ Foxp3+ T cells contributes to their regulatory function

21 January 2018

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Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study

21 January 2018

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Deficiency of CD73/ecto-5'-nucleotidase in mice enhances acute graft-versus-host disease

21 January 2018

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Graft-versus-host disease is enhanced by selective CD73 blockade in mice

21 January 2018

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Mesenchymal stromal cell 'licensing': a multistep process

21 January 2018

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Adenosine and kidney function.

21 January 2018

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Adenosine generation and signaling during acute kidney injury

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/STEM.2280

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28 February 2018

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28 February 2018