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2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 binds GRB2-1:SOS1
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-8853734)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8853734
part of
RET signaling
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8853734
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8853734
exact match
https://identifiers.org/reactome:R-HSA-8853734
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8853734
has part(s)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8853734
GRB2-1:SOS1 [cytosol]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8853734
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1:SOS1 [plasma membrane]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8853734
cites work
Signaling complexes and protein-protein interactions involved in the activation of the Ras and phosphatidylinositol 3-kinase pathways by the c-Ret receptor tyrosine kinase.
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8853734
Characterization of Ret-Shc-Grb2 complex induced by GDNF, MEN 2A, and MEN 2B mutations
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8853734
Identifiers
Reactome ID
R-HSA-8853734
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8853734
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