(Q50291745)

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Caspase-8 processing within TLR3 complex

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-9013895)

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8 July 2022

apoptotic signaling pathway

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8 July 2022

TLR3-mediated TICAM1-dependent programmed cell death

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8 July 2022

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8 July 2022

https://identifiers.org/reactome:R-HSA-9013895

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8 July 2022

activated TLR3:TRIF:RIP1:FADD:pro-caspase-8 [endosome membrane]

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8 July 2022

activated TLR3:TRIF:RIP1:FADD [endosome membrane]

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8 July 2022

active caspase-8 [cytosol]

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8 July 2022

activated TLR3:TRIF:RIP1:FADD:pro-caspase-8 [endosome membrane]

1

1 reference

8 July 2022

cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms

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8 July 2022

Structural and biochemical studies on procaspase-8: new insights on initiator caspase activation

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8 July 2022

Insights into the regulatory mechanism for caspase-8 activation

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8 July 2022

Apoptosis induced by the toll-like receptor adaptor TRIF is dependent on its receptor interacting protein homotypic interaction motif

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8 July 2022

Inducible dimerization and inducible cleavage reveal a requirement for both processes in caspase-8 activation

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8 July 2022

dsRNA induces apoptosis through an atypical death complex associating TLR3 to caspase-8.

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8 July 2022

Tipping the balance between necrosis and apoptosis in human and murine cells treated with interferon and dsRNA.

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8 July 2022

Identifiers

1 reference

8 July 2022

(Q50291745)

Caspase-8 processing within TLR3 complex

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