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Tipping the balance between necrosis and apoptosis in human and murine cells treated with interferon and dsRNA.
scientific article published in September 2002
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1 reference
stated in
Europe PubMed Central
PubMed ID
12181749
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12181749%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
title
Tipping the balance between necrosis and apoptosis in human and murine cells treated with interferon and dsRNA
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
12181749
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12181749%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
main subject
apoptotic process
1 reference
based on heuristic
inferred from title
author
Tom Vanden Berghe
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed ID
12181749
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12181749%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
Peter Vandenabeele
series ordinal
7
1 reference
stated in
Europe PubMed Central
PubMed ID
12181749
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12181749%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
Xavier Saelens
series ordinal
6
object named as
Saelens X
1 reference
stated in
Europe PubMed Central
PubMed ID
12181749
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12181749%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
author name string
Kalai M
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
12181749
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12181749%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
Van Loo G
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
12181749
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12181749%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
Meeus A
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed ID
12181749
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12181749%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
Burm W
series ordinal
5
1 reference
stated in
Europe PubMed Central
PubMed ID
12181749
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12181749%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
publication date
1 September 2002
1 reference
stated in
Europe PubMed Central
PubMed ID
12181749
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12181749%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
published in
Cell Death & Differentiation
1 reference
stated in
Europe PubMed Central
PubMed ID
12181749
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12181749%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
volume
9
1 reference
stated in
Europe PubMed Central
PubMed ID
12181749
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12181749%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
issue
9
1 reference
stated in
Europe PubMed Central
PubMed ID
12181749
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12181749%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
page(s)
981-994
1 reference
stated in
Europe PubMed Central
PubMed ID
12181749
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12181749%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
exact match
https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401051
0 references
cites work
How cells respond to interferons
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Crossref
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Noncytolytic control of viral infections by the innate and adaptive immune response
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When two strands are better than one: the mediators and modulators of the cellular responses to double-stranded RNA.
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7 January 2021
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JNK2 and IKKbeta are required for activating the innate response to viral infection
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Crossref
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
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7 January 2021
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Building better vaccines: how apoptotic cell death can induce inflammation and activate innate and adaptive immunity
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
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7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of interferon by "Sepharose"-bound poly(I)-poly(C)
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
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7 January 2021
based on heuristic
inferred from DOI database lookup
Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Sepharose-bound poly (I)-poly (C): interaction with cells and interferon production
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
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7 January 2021
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inferred from DOI database lookup
The Toxic Effect of Double-stranded RNA for Interferon-treated Cells: Evidence for a Heterogeneous Cellular Response and the Role of the Cell Nucleus
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
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7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the dsRNA-dependent protein kinase, PKR, induces apoptosis through FADD-mediated death signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Type I interferons are essential mediators of apoptotic death in virally infected cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alpha/beta interferons potentiate virus-induced apoptosis through activation of the FADD/Caspase-8 death signaling pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
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7 January 2021
based on heuristic
inferred from DOI database lookup
A study of the interferon antiviral mechanism: apoptosis activation by the 2-5A system
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
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7 January 2021
based on heuristic
inferred from DOI database lookup
A double-stranded RNA-activated protein kinase-dependent pathway mediating stress-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the IFN-inducible enzyme RNase L causes apoptosis of animal cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Direct evidence for tumor necrosis factor-induced mitochondrial reactive oxygen intermediates and their involvement in cytotoxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
More than one way to die: apoptosis, necrosis and reactive oxygen damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of reactive oxygen species (ROS) in apoptosis induction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
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7 January 2021
based on heuristic
inferred from DOI database lookup
The central effectors of cell death in the immune system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
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7 January 2021
based on heuristic
inferred from DOI database lookup
Gone but not forgotten
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis and cancer: strategies for integrating programmed cell death
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial physiology and pathology; concepts of programmed death of organelles, cells and organisms
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondria as the central control point of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interdigital cell death can occur through a necrotic and caspase-independent pathway.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-independent programmed cell death with necrotic morphology
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-independent cell killing by Fas-associated protein with death domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
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7 January 2021
based on heuristic
inferred from DOI database lookup
Dual signaling of the Fas receptor: initiation of both apoptotic and necrotic cell death pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Resistance to the cytotoxic effects of tumor necrosis factor alpha can be overcome by inhibition of a FADD/caspase-dependent signaling pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure/Function analysis of p55 tumor necrosis factor receptor and fas-associated death domain. Effect on necrosis in L929sA cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
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7 January 2021
based on heuristic
inferred from DOI database lookup
Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sensitization to death receptor cytotoxicity by inhibition of fas-associated death domain protein (FADD)/caspase signaling. Requirement of cell cycle progression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
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7 January 2021
based on heuristic
inferred from DOI database lookup
Necrotic death pathway in Fas receptor signaling
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TRAIL receptor-2 signals apoptosis through FADD and caspase-8
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
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7 January 2021
based on heuristic
inferred from DOI database lookup
FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
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7 January 2021
based on heuristic
inferred from DOI database lookup
Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Disruption of hsp90 function results in degradation of the death domain kinase, receptor-interacting protein (RIP), and blockage of tumor necrosis factor-induced nuclear factor-kappaB activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulated commitment of TNF receptor signaling: a molecular switch for death or activation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
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7 January 2021
based on heuristic
inferred from DOI database lookup
Interferon alpha augments activation-induced T cell death by upregulation of Fas (CD95/APO-1) and Fas ligand expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The interferons and cell death: guardians of the cell or accomplices of apoptosis?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lithium chloride potentiates tumor necrosis factor-mediated cytotoxicity in vitro and in vivo
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase inhibitors.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of Fas-induced apoptosis by Bcl-2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms controlling cellular suicide: role of Bcl-2 and caspases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential role of caspase-8 and BID activation during radiation- and CD95-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cleavage of BID during cytotoxic drug and UV radiation-induced apoptosis occurs downstream of the point of Bcl-2 action and is catalysed by caspase-3: a potential feedback loop for amplification of apoptosis-associated mitochondrial cytochrome c rel
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hsp90: chaperoning signal transduction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Double-stranded RNA inhibits beta-cell function and induces islet damage by stimulating beta-cell production of nitric oxide
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms of beta-cell death in response to double-stranded (ds) RNA and interferon-gamma: dsRNA-dependent protein kinase apoptosis and nitric oxide-dependent necrosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TNF-alpha activates at least two apoptotic signaling cascades
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Death receptor-induced apoptotic and necrotic cell death: differential role of caspases and mitochondria.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Virus clearance through apoptosis-dependent phagocytosis of influenza A virus-infected cells by macrophages
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis: an innate immune response to virus infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The apoptotic signaling pathway activated by Toll-like receptor-2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Drosophila MyD88 is an adapter in the Toll signaling pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Autoimmune insulitis and diabetes in the absence of antigen-specific contact between T cells and islet beta-cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Virus-induced autoimmune diabetes: most beta-cells die through inflammatory cytokines and not perforin from autoreactive (anti-viral) cytotoxic T-lymphocytes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytokines and their roles in pancreatic islet beta-cell destruction and insulin-dependent diabetes mellitus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Double-stranded RNA-dependent protein kinase is not required for double-stranded RNA-induced nitric oxide synthase expression or nuclear factor-kappaB activation by islets
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Insulin-dependent diabetes mellitus during alpha-interferon therapy for chronic viral hepatitis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interferon-gamma plays a role in pancreatic islet-cell destruction of reovirus type 2-induced diabetes-like syndrome in DBA/1 suckling mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An improved colorimetric assay for interleukin 2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401051
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.CDD.4401051
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/u43gq2oonjcybdbi3qha4ei4oe
retrieved
30 July 2022
based on heuristic
mapped directly with Wikidata item
Fatcat ID
release_u43gq2oonjcybdbi3qha4ei4oe
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/u43gq2oonjcybdbi3qha4ei4oe
retrieved
30 July 2022
based on heuristic
mapped directly with Wikidata item
PubMed ID
12181749
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/u43gq2oonjcybdbi3qha4ei4oe
retrieved
30 July 2022
based on heuristic
mapped directly with Wikidata item
ResearchGate publication ID
11205139
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